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Prof. Dr. Marc Hübner

Member

Institute for Medical Microbiology, Immunology and Parasitology

huebner@uni-bonn.de

+49 228 28719177

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My lab focuses on different aspects of helminth (worm) infections: 1) Protective immune responses against filariae and especially the protective role of eosinophils and the contribution of extracellular DNA traps (ETosis), 2) Filarial immunomodulation and its beneficial impact on life-style diseases such as diet-induced insulin resistance, 3) Preclinical testing of drug candidates for filariasis in order to identify novel macrofilaricidal drugs in collaboration with partners from industry and not-for-profit-organizations. For these investigations we use the Litomosoides sigmodontis rodent model and perform human studies with filariasis patients in sub-Saharan Africa.

Marc Hübner

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Recent publications

  • Expert consensus on case definitions in human loiasis: a Delphi study.

    The Lancet. Infectious diseases

    Authors: Luzia Veletzky, Spinello Antinori, Sabine Bélard, Marielle Bouyou, Emmanuel Bottieau, Jérémy T Campillo, Cédric B Chesnais, Fernando de la Calle-Prieto, Federico Gobbi, Marc P Hübner, Amy D Klion, Pia Michelitsch, Andreas Neumayr, Tamara Nordmann, Thomas B Nutman, Fernando Salvador, Stephen D Vaughan, Michael Ramharter, Francesca Tamarozzi

  • Efficacy of oxfendazole treatment against infective larvae of Litomosoides sigmodontis.

    PLoS neglected tropical diseases

    Authors: Frederic Risch, Lucas J Bergmann, Hannah R Wegner, Achim Hoerauf, Marc P Hübner

  • Design and analysis of randomized clinical trials for onchocerciasis, loiasis and mansonellosis: A systematic review.

    PLoS neglected tropical diseases

    Authors: Fabrice Lotola Mougeni, Marta Bofill Roig, Marc P Hübner, Ute Klarmann-Schulz, Benjamin Lenz, Sabine Specht, Martin Posch, Sonja Zehetmayer

All publications by Prof. Dr. Marc Hübner