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Prof. Dr. Marc Hübner

Member

Institute for Medical Microbiology, Immunology and Parasitology

huebner@uni-bonn.de

+49 228 28719177

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My lab focuses on different aspects of helminth (worm) infections: 1) Protective immune responses against filariae and especially the protective role of eosinophils and the contribution of extracellular DNA traps (ETosis), 2) Filarial immunomodulation and its beneficial impact on life-style diseases such as diet-induced insulin resistance, 3) Preclinical testing of drug candidates for filariasis in order to identify novel macrofilaricidal drugs in collaboration with partners from industry and not-for-profit-organizations. For these investigations we use the Litomosoides sigmodontis rodent model and perform human studies with filariasis patients in sub-Saharan Africa.

Marc Hübner

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Recent publications

  • Differences of in vitro immune responses between patent and pre-patent Litomosoides sigmodontis-infected mice are independent of the filarial antigenic stimulus used.

    Parasitology research

    Authors: Kathrin Arndts, Anna Wiszniewsky, Anna-Lena Neumann, Katharina Wiszniewsky, Gnatoulma Katawa, Achim Hoerauf, Laura E Layland-Heni, Manuel Ritter, Marc P Hübner

  • The long and winding road towards new treatments against lymphatic filariasis and onchocerciasis.

    Trends in parasitology

    Authors: Frederic Risch, Alexander Kazakov, Sabine Specht, Kenneth Pfarr, Peter U Fischer, Achim Hoerauf, Marc P Hübner

  • Seroprevalence and Association of with Bone Health in a Cohort of Osteopenia and Osteoporosis Patients.

    Biomedicines

    Authors: Indulekha Karunakaran, Jayagopi Surendar, Pia Ransmann, Marius Brühl, Silvia Kowalski, Victoria Frische, Jamil Hmida, Sabine Nachtsheim, Achim Hoerauf, Dieter C Wirtz, Marc P Hübner, Andreas C Strauss, Frank A Schildberg

All publications by Prof. Dr. Marc Hübner