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Prof. Dr. Marc Hübner

Member

Institute for Medical Microbiology, Immunology and Parasitology

huebner@uni-bonn.de

+49 228 28719177

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My lab focuses on different aspects of helminth (worm) infections: 1) Protective immune responses against filariae and especially the protective role of eosinophils and the contribution of extracellular DNA traps (ETosis), 2) Filarial immunomodulation and its beneficial impact on life-style diseases such as diet-induced insulin resistance, 3) Preclinical testing of drug candidates for filariasis in order to identify novel macrofilaricidal drugs in collaboration with partners from industry and not-for-profit-organizations. For these investigations we use the Litomosoides sigmodontis rodent model and perform human studies with filariasis patients in sub-Saharan Africa.

Marc Hübner

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Recent publications

  • Epidemiology of helminth infections in adults in rural rainforest communities of the Nkam-Wouri River Basin, Littoral Region of Cameroon: Implications for NTDs elimination using preventive chemotherapies.

    PLoS neglected tropical diseases

    Authors: Anita Bate Obi Ebob, Narcisse Victor Tchamatchoua Gandjui, Benjamin Lenz, Emmanuel Ouam, Juluis Visnel Foyet, Amuam Andrew Beng, Fanny Fri Fombad, Franck Noel Nietcho, Manuel Ritter, Indulekha Karunakaran, Ndialle Nordine Mponge, Lucy Cho Nchang, Cheng Wang, Fonyuy Brandon Tahnteng, Jerome Fru Cho, Mathias Eyong Esum, Tatiana Djikeussi Katcho, Achim Hoerauf, Marc P Hübner, Samuel Wanji

  • Laboratory diagnosis of loiasis to support individual patient management: A systematic review.

    PLoS neglected tropical diseases

    Authors: Luzia Veletzky, Marc P Hübner, Cristina Mazzi, Veronica A Fittipaldo, Marielle Bouyou-Akotet, Federico Gobbi, Michael Ramharter, Francesca Tamarozzi

  • Expert consensus on case definitions in human loiasis: a Delphi study.

    The Lancet. Infectious diseases

    Authors: Luzia Veletzky, Spinello Antinori, Sabine Bélard, Marielle Bouyou, Emmanuel Bottieau, Jérémy T Campillo, Cédric B Chesnais, Fernando de la Calle-Prieto, Federico Gobbi, Marc P Hübner, Amy D Klion, Pia Michelitsch, Andreas Neumayr, Tamara Nordmann, Thomas B Nutman, Fernando Salvador, Stephen D Vaughan, Michael Ramharter, Francesca Tamarozzi

All publications by Prof. Dr. Marc Hübner