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Prof. Dr. Marc Hübner

Member

Institute for Medical Microbiology, Immunology and Parasitology

huebner@uni-bonn.de

+49 228 28719177

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My lab focuses on different aspects of helminth (worm) infections: 1) Protective immune responses against filariae and especially the protective role of eosinophils and the contribution of extracellular DNA traps (ETosis), 2) Filarial immunomodulation and its beneficial impact on life-style diseases such as diet-induced insulin resistance, 3) Preclinical testing of drug candidates for filariasis in order to identify novel macrofilaricidal drugs in collaboration with partners from industry and not-for-profit-organizations. For these investigations we use the Litomosoides sigmodontis rodent model and perform human studies with filariasis patients in sub-Saharan Africa.

Marc Hübner

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Recent publications

  • Design and analysis of randomized clinical trials for onchocerciasis, loiasis and mansonellosis: A systematic review.

    PLoS neglected tropical diseases

    Authors: Fabrice Lotola Mougeni, Marta Bofill Roig, Marc P Hübner, Ute Klarmann-Schulz, Benjamin Lenz, Sabine Specht, Martin Posch, Sonja Zehetmayer

  • Cytokine-induced killer (CIK) cells inhibit Plasmodium falciparum parasitemia through cytolytic effector activity in vitro.

    Immunobiology

    Authors: Rohulla Vaseq, Berthila Ferkamchwi, Hans Weiher, Veronika Lukacs-Kornek, Nahid Mahleqa, Marc P Hübner, Amit Sharma, Ingo G H Schmidt-Wolf

  • Temporal dynamics of SARS-CoV-2 antibodies and IgG subclasses following multiple doses and diverse COVID-19 vaccine combinations.

    Frontiers in immunology

    Authors: Julia Meyer, Achim Hoerauf, Aleksandra Elzbieta Dubiel, Peđa Kovačević, Anika Trudić, Dragan Primorac, Marc P Hübner, Tomabu Adjobimey, Marijo Parcina

All publications by Prof. Dr. Marc Hübner