Skip to main content

Prof. Dr. Monique Breteler

Member, Steering-Committee Member

German Center for Neurodegenerative Diseases (DZNE)

Sigmund-Freud-Str. 27 53127 Bonn

monique.breteler@dzne.de

+49 228 43302929

Website

Our research uses an epidemiological approach to investigating the fundamentals of healthy aging and the chang-es that take place in the brain during the course of our lives. Using large-scale population-imaging studies, we study the role of vascular mechanisms, metabolic disorders, inflammation and lifestyle factors in the development and progression of neurodegenerative diseases, with a focus on early identification and prevention of disease.

Monique Breteler

Download biosketch

Recent publications

  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

  • Effects of Physical Activity on Brain White Matter Integrity Are Region-, Dose-, and Age-Dependent: Findings From the Population-Based Rhineland Study.

    Aging cell

    Authors: Eva Saxler, Fabienne A U Fox, Alexandra Koch, Xingwang Yang, Weiyi Zeng, Santiago Estrada, Monique M B Breteler, N Ahmad Aziz

  • Genome-wide association studies of missing metabolite measures from two population-based studies.

    Genome biology

    Authors: Tariq O Faquih, Mohammed Aslam Imtiaz, Valentina Talevi, Elvire N Landstra, Astrid van Hylckama Vlieg, Ruifang Li-Gao, Frits R Rosendaal, Raymond Noordam, Diana van Heemst, Dennis O Mook-Kanamori, Monique M B Breteler, N Ahmad Aziz, Ko Willems van Dijk

All publications by Prof. Dr. Monique Breteler