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Prof. Dr. Monique Breteler

Member, Steering-Committee Member

German Center for Neurodegenerative Diseases (DZNE)

Sigmund-Freud-Str. 27 53127 Bonn

monique.breteler@dzne.de

+49 228 43302929

Website

Our research uses an epidemiological approach to investigating the fundamentals of healthy aging and the chang-es that take place in the brain during the course of our lives. Using large-scale population-imaging studies, we study the role of vascular mechanisms, metabolic disorders, inflammation and lifestyle factors in the development and progression of neurodegenerative diseases, with a focus on early identification and prevention of disease.

Recent publications

  • DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general population.

    EBioMedicine

    Authors: Dan Liu, Valentina Talevi, Juliana F Tavares, Ruiqi Wang, Mohammed A Imtiaz, Konstantinos Melas, Alexander Teumer, Katharina Wittfeld, Robert F Hillary, Dina Vojinovic, Marian Beekman, Nicola J Armstrong, Santiago Estrada, Henry Völzke, Robin Bülow, Natalie A Royle, Joanna M Wardlaw, Wei Wen, Perminder S Sachdev, Karen A Mather, P Eline Slagboom, Simon R Cox, Hans Jörgen Grabe, Qiong Yang, N Ahmad Aziz, Monique M B Breteler

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  • Population-based genome-wide association study of plasma complex lipid species.

    Nature communications

    Authors: Elvire N Landstra, Mohammed A Imtiaz, Valentina Talevi, Fabian Eichelmann, Matthias B Schulze, N Ahmad Aziz, Monique M B Breteler

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  • Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: findings from the Rhineland Study.

    Molecular psychiatry

    Authors: Konstantinos Melas, Valentina Talevi, Mohammed Aslam Imtiaz, Dennis M Krüger, Tonatiuh Pena-Centeno, André Fischer, N Ahmad Aziz, Monique M B Breteler

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