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Prof. Dr. Monique Breteler

Member, Steering-Committee Member

German Center for Neurodegenerative Diseases (DZNE)

Sigmund-Freud-Str. 27 53127 Bonn

monique.breteler@dzne.de

+49 228 43302929

Website

Our research uses an epidemiological approach to investigating the fundamentals of healthy aging and the chang-es that take place in the brain during the course of our lives. Using large-scale population-imaging studies, we study the role of vascular mechanisms, metabolic disorders, inflammation and lifestyle factors in the development and progression of neurodegenerative diseases, with a focus on early identification and prevention of disease.

Recent publications

  • The growing burden of myopia in Europe: evidence from population-based cohorts.

    European journal of epidemiology

    Authors: Amber Tiemens, Dirk J van Hemert, Sena T Lemma, Sara W Quist, Kun Shi-van Wielink, David Agius, Louis Arnould, Tos T J M Berendschot, Ansgar Beuse, Mukharram M Bikbov, Johannes Birtel, Vasiliki Bountziouka, Monique M B Breteler, Francis Carbonaro, Usha Chakravarthy, Rita Coimbra, Victor A de Vries, Cécile Delcourt, Claudia Farinha, Robert P Finger, Mohsen Ghanbari, Dimitris A Giannoulis, Carsten Grohmann, Chris J Hammond, Frank G Holz, Jost B Jonas, Gyulli M Kazakbaeva, Anthony P Khawaja, Toralf Kirsten, Sander C M Kneepkens, Simon C König, Melanie Le Goff, Johanna Liinamaa, Julian Mamo, Matthias M Mauschitz, Jan Roelof Polling, Jugnoo S Rahi, Franziska G Rauscher, Ville Saarela, Alexander K Schuster, Kelsey V Stuart, Fotis Topouzis, Freekje van Asten, Anna Maria Welzel, Peter Wolfrum, Caroline C W Klaver, Katie M Williams

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  • Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts.

    Nature communications

    Authors: Juliana F Tavares, Dan Liu, Valentina Talevi, Fabian Eichelmann, Franziska Jannasch, Matthias B Schulze, N Ahmad Aziz, Ute Nöthlings, Monique M B Breteler

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  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

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