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featured publications

  • Associations between diet quality, epigenetic aging and epigenome in two population-based cohorts.

    Nature communications

    Authors: Juliana F Tavares, Dan Liu, Valentina Talevi, Fabian Eichelmann, Franziska Jannasch, Matthias B Schulze, N Ahmad Aziz, Ute Nöthlings, Monique M B Breteler

  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

  • Effects of Physical Activity on Brain White Matter Integrity Are Region-, Dose-, and Age-Dependent: Findings From the Population-Based Rhineland Study.

    Aging cell

    Authors: Eva Saxler, Fabienne A U Fox, Alexandra Koch, Xingwang Yang, Weiyi Zeng, Santiago Estrada, Monique M B Breteler, N Ahmad Aziz

  • Genome-wide association studies of missing metabolite measures from two population-based studies.

    Genome biology

    Authors: Tariq O Faquih, Mohammed Aslam Imtiaz, Valentina Talevi, Elvire N Landstra, Astrid van Hylckama Vlieg, Ruifang Li-Gao, Frits R Rosendaal, Raymond Noordam, Diana van Heemst, Dennis O Mook-Kanamori, Monique M B Breteler, N Ahmad Aziz, Ko Willems van Dijk

  • Tandem repeat polymorphisms are associated with brain structure: results of two large population-based studies.

    Genome medicine

    Authors: Richard Mantey, Jialu Hu, Maryam Touhidinia, Tanzeem Butt, Ahmed Mokhtar Sidky, Roohollah Sobhani, Santiago Estrada, Kristian Haendler, Elena De Domenico, Marc Daniel Beyer, Monique Maria Bernadette Breteler, Nasir Ahmad Aziz

  • Large-scale analysis of temporal gene expression variation in peripheral blood.

    Nature communications

    Authors: Neha Mishra, Franziska Kimmig, Doris Vandeputte, Valentina Talevi, Lindsey De Commer, Chloe Verspecht, Arnau Vich Vila, Julia S El-Sayed Moustafa, Lukasz Kreft, Alexander Botzki, Youssef El Darzi, Sebastian Proost, Lindsay Devolder, Dongmeng Wang, Joana P Bernardes, N Ahmad Aziz, Andre Franke, Stefan Schreiber, Emmanouil T Dermitzakis, Sara Vieira-Silva, Gwen Falony, Kerrin S Small, Monique M B Breteler, Joachim L Schultze, Jeroen Raes, Philip Rosenstiel

  • DNA methylation signatures of bilateral hippocampal volume, asymmetry and atrophy: a cross-omics analysis in the general population.

    EBioMedicine

    Authors: Dan Liu, Valentina Talevi, Juliana F Tavares, Ruiqi Wang, Mohammed A Imtiaz, Konstantinos Melas, Alexander Teumer, Katharina Wittfeld, Robert F Hillary, Dina Vojinovic, Marian Beekman, Nicola J Armstrong, Santiago Estrada, Henry Völzke, Robin Bülow, Natalie A Royle, Joanna M Wardlaw, Wei Wen, Perminder S Sachdev, Karen A Mather, P Eline Slagboom, Simon R Cox, Hans Jörgen Grabe, Qiong Yang, N Ahmad Aziz, Monique M B Breteler

  • Population-based genome-wide association study of plasma complex lipid species.

    Nature communications

    Authors: Elvire N Landstra, Mohammed A Imtiaz, Valentina Talevi, Fabian Eichelmann, Matthias B Schulze, N Ahmad Aziz, Monique M B Breteler

  • Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: findings from the Rhineland Study.

    Molecular psychiatry

    Authors: Konstantinos Melas, Valentina Talevi, Mohammed Aslam Imtiaz, Dennis M Krüger, Tonatiuh Pena-Centeno, André Fischer, N Ahmad Aziz, Monique M B Breteler

  • Plasma complex lipids in relation to cortical thickness and brain volumes: results from the population-based Rhineland study.

    Lipids in health and disease

    Authors: Elvire N Landstra, Valerie Lohner, Juliana F Tavares, Kersten Diers, Alexandra Koch, Monique M B Breteler