Institute of Clinical Chemistry and Clinical Pharmacology
Medical Faculty, University of Bonn University Hospital of Bonn Sigmund-Freud-Strasse 25 53105 Bonn
We investigate under which conditions endogenous nucleic acids can activate nucleic acid sensors of the innate immune system. Over the last 20 years innate immune recognition of nucleic acids has been established as a central mechanism driving inflammation of sterile and of infectious etiologies. In the future, we will build upon the knowledge gained from studying disease to understand the role of nucleic acid immunity in health.
