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Prof. Dr. Zeinab Abdullah

Member, Steering-Committee Member

Institute of Experimental Immunology (IEI)

Medical Faculty, University of Bonn University Hospital of Bonn Sigmund-Freud-Strasse 25 53105 Bonn

zeinab.abdullah@uni-bonn.de

+49 228 28711138

Website

The overall goal of our research is to understand the molecular cellular mechanisms by which chronic inflammation can affect outcome of infection and immune cell function. Specifically, the research focuses on mechanistic studies to understand the impact of chronic inflammation during liver fibrosis on the function of hepatic myeloid cells in host defence and adaptive immune responses against de novo infections.

Zeinab Abdullah

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Recent publications

  • Transcriptional regulator SATB1 limits CD8 T cell population expansion and effector differentiation in chronic infection and cancer.

    Nature immunology

    Authors: Leonie Heyden, Lisa Rausch, Michael H Shannon, Lachlan Dryburgh, Marcela L Moreira, Aleksej Frolov, Christina M Scheffler, Marit J van Elsas, Junming Tong, Olivia Hidajat, Sharanya K M Wijesinghe, Sining Li, Helena Horvatic, Nhat Truong Huynh-Anh, Catarina Gago da Graça, Carlson Tsui, Maren Köhne, Daniel Sommer, F Thomas Wunderlich, Bianca von Scheidt, Simone L Park, Laura K Mackay, Daniel T Utzschneider, Jan Schröder, Stephen J Turner, Phillip K Darcy, Marc D Beyer, Zeinab Abdullah, Axel Kallies

  • Lymph nodes fuel KLF2-dependent effector CD8 T cell differentiation during chronic infection and checkpoint blockade.

    Nature immunology

    Authors: Carlson Tsui, Leonie Heyden, Lifen Wen, Catarina Gago da Graça, Nikita Potemkin, Aleksej Frolov, Daniel Rawlinson, Lei Qin, Verena C Wimmer, Marjan Hadian-Jazi, Darya Malko, Chun-Hsi Su, Sining Li, Kayla R Wilson, Helena Horvatic, Sharanya K Wijesinghe, Marcela L Moreira, Lachlan Dryburgh, Dominik Schienstock, Lisa Rausch, Daniel T Utzschneider, Cornelia Halin, Scott N Mueller, Marc D Beyer, Sammy Bedoui, Zeinab Abdullah, Jan Schröder, Axel Kallies

  • ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.

    Cell reports

    Authors: Ole Kristian Greiner-Tollersrud, Máté Krausz, Vincent Boehler, Aikaterini Polyzou, Maximilian Seidl, Ambra Spahiu, Zeinab Abdullah, Katarzyna Andryka-Cegielski, Felix Immunuel Dominick, Katrin Huebscher, Andreas Goschin, Cristian R Smulski, Eirini Trompouki, Regina Link, Hilmar Ebersbach, Honnappa Srinivas, Martine Marchant, Georgios Sogkas, Dieter Staab, Cathrine Vågbø, Danilo Guerini, Sebastian Baasch, Eicke Latz, Gunther Hartmann, Philippe Henneke, Roger Geiger, Xiao P Peng, Bodo Grimbacher, Eva Bartok, Ingrun Alseth, Max Warncke, Michele Proietti

All publications by Prof. Dr. Zeinab Abdullah