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Prof. Dr. Zeinab Abdullah

Member, Steering-Committee Member

Institute of Experimental Immunology (IEI)

Medical Faculty, University of Bonn University Hospital of Bonn Sigmund-Freud-Strasse 25 53105 Bonn

zeinab.abdullah@uni-bonn.de

+49 228 28711138

Website

The overall goal of our research is to understand the molecular cellular mechanisms by which chronic inflammation can affect outcome of infection and immune cell function. Specifically, the research focuses on mechanistic studies to understand the impact of chronic inflammation during liver fibrosis on the function of hepatic myeloid cells in host defence and adaptive immune responses against de novo infections.

Zeinab Abdullah

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Recent publications

  • B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection.

    Immunity

    Authors: Catarina Gago da Graça, Yuxi Cao, Sining Li, Anna F Lindemann, Leonie Heyden, Sharanya K M Wijesinghe, Annika Poch, Minh-Hanh T Nguyen, Nhat T Huynh-Anh, Elena Daum, Danielle Chen, Carlson Tsui, Erandi Rupasinghe, Michael P Gantier, Axel Roers, Robert Thimme, Maike Hofmann, Sammy Bedoui, Zeinab Abdullah, Jan Schröder, Axel Kallies, Yannick O Alexandre, Daniel T Utzschneider

  • A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation.

    Nature communications

    Authors: Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar, Subhendu Som, Luisa Bach, Peter Konopka, Eliška Miková, Shaunak Ghosh, Jan Böthling, Mirka Homrich, Laura Schaedel, Uli Kazmaier, Konstantinos Symeonidis, Stefan Ebner, Philip Weidner, Zeinab Abdullah, Felix Meissner, Stefan Uderhardt, Miroslav Hons, Dirk Baumjohann, Raja Paul, Heiko Rieger, Eva Kiermaier

  • Transcriptional regulator SATB1 limits CD8 T cell population expansion and effector differentiation in chronic infection and cancer.

    Nature immunology

    Authors: Leonie Heyden, Lisa Rausch, Michael H Shannon, Lachlan Dryburgh, Marcela L Moreira, Aleksej Frolov, Christina M Scheffler, Marit J van Elsas, Junming Tong, Olivia Hidajat, Sharanya K M Wijesinghe, Sining Li, Helena Horvatic, Nhat Truong Huynh-Anh, Catarina Gago da Graça, Carlson Tsui, Maren Köhne, Daniel Sommer, F Thomas Wunderlich, Bianca von Scheidt, Simone L Park, Laura K Mackay, Daniel T Utzschneider, Jan Schröder, Stephen J Turner, Phillip K Darcy, Marc D Beyer, Zeinab Abdullah, Axel Kallies

All publications by Prof. Dr. Zeinab Abdullah