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featured publications

  • G-quadruplex structures affect the immune response to bacterial infection in mouse macrophages.

    Nature communications

    Authors: Philipp Schult, Melanie Kastl, Jennifer Szlapa, Konstantinos Symeonidis, Salie Maasewerd, Bernardo Franklin, Alea Radcke, Stefan A Juranek, Zeinab Abdullah, Katrin Paeschke

  • Adipose ILC2s depend on acetyl-CoA carboxylase 1 to maintain metabolic health.

    Cell metabolism

    Authors: Fotios Karagiannis, Maria Rafailia Theodorou, Fabian Nikolka, Maria Doverman, Dhruvi Shah, Chantal Wientjens, Timothy R McCulloch, Ronja Kardinal, David Colon, Jelena Zurkovic, Jiangyan Yu, Julia Anna Noras, Patricia Weiss, Roman Rombo, Tim Sparwasser, Zeinab Abdullah, Felix Meissner, Christoph Thiele, Jan Hasenauer, Dagmar Wachten, Karsten Hiller, Christoph Wilhelm

  • B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection.

    Immunity

    Authors: Catarina Gago da Graça, Yuxi Cao, Sining Li, Anna F Lindemann, Leonie Heyden, Sharanya K M Wijesinghe, Annika Poch, Minh-Hanh T Nguyen, Nhat T Huynh-Anh, Elena Daum, Danielle Chen, Carlson Tsui, Erandi Rupasinghe, Michael P Gantier, Axel Roers, Robert Thimme, Maike Hofmann, Sammy Bedoui, Zeinab Abdullah, Jan Schröder, Axel Kallies, Yannick O Alexandre, Daniel T Utzschneider

  • A centrally positioned cluster of multiple centrioles in antigen-presenting cells fosters T cell activation.

    Nature communications

    Authors: Isabel Stötzel, Ann-Kathrin Weier, Apurba Sarkar, Subhendu Som, Luisa Bach, Peter Konopka, Eliška Miková, Shaunak Ghosh, Jan Böthling, Mirka Homrich, Laura Schaedel, Uli Kazmaier, Konstantinos Symeonidis, Stefan Ebner, Philip Weidner, Zeinab Abdullah, Felix Meissner, Stefan Uderhardt, Miroslav Hons, Dirk Baumjohann, Raja Paul, Heiko Rieger, Eva Kiermaier

  • Transcriptional regulator SATB1 limits CD8 T cell population expansion and effector differentiation in chronic infection and cancer.

    Nature immunology

    Authors: Leonie Heyden, Lisa Rausch, Michael H Shannon, Lachlan Dryburgh, Marcela L Moreira, Aleksej Frolov, Christina M Scheffler, Marit J van Elsas, Junming Tong, Olivia Hidajat, Sharanya K M Wijesinghe, Sining Li, Helena Horvatic, Nhat Truong Huynh-Anh, Catarina Gago da Graça, Carlson Tsui, Maren Köhne, Daniel Sommer, F Thomas Wunderlich, Bianca von Scheidt, Simone L Park, Laura K Mackay, Daniel T Utzschneider, Jan Schröder, Stephen J Turner, Phillip K Darcy, Marc D Beyer, Zeinab Abdullah, Axel Kallies

  • Lymph nodes fuel KLF2-dependent effector CD8 T cell differentiation during chronic infection and checkpoint blockade.

    Nature immunology

    Authors: Carlson Tsui, Leonie Heyden, Lifen Wen, Catarina Gago da Graça, Nikita Potemkin, Aleksej Frolov, Daniel Rawlinson, Lei Qin, Verena C Wimmer, Marjan Hadian-Jazi, Darya Malko, Chun-Hsi Su, Sining Li, Kayla R Wilson, Helena Horvatic, Sharanya K Wijesinghe, Marcela L Moreira, Lachlan Dryburgh, Dominik Schienstock, Lisa Rausch, Daniel T Utzschneider, Cornelia Halin, Scott N Mueller, Marc D Beyer, Sammy Bedoui, Zeinab Abdullah, Jan Schröder, Axel Kallies

  • ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.

    Cell reports

    Authors: Ole Kristian Greiner-Tollersrud, Máté Krausz, Vincent Boehler, Aikaterini Polyzou, Maximilian Seidl, Ambra Spahiu, Zeinab Abdullah, Katarzyna Andryka-Cegielski, Felix Immunuel Dominick, Katrin Huebscher, Andreas Goschin, Cristian R Smulski, Eirini Trompouki, Regina Link, Hilmar Ebersbach, Honnappa Srinivas, Martine Marchant, Georgios Sogkas, Dieter Staab, Cathrine Vågbø, Danilo Guerini, Sebastian Baasch, Eicke Latz, Gunther Hartmann, Philippe Henneke, Roger Geiger, Xiao P Peng, Bodo Grimbacher, Eva Bartok, Ingrun Alseth, Max Warncke, Michele Proietti

  • Autofluorescence-based tissue characterization enhances clinical prospects of light-sheet-microscopy.

    Scientific reports

    Authors: Alice M Jacob, Anna F Lindemann, Julia Wagenpfeil, Sergej Geiger, Yannik C Layer, Babak Salam, Sarah Panahabadi, Darius Kurt, Maximilian W M Wintergerst, Frank A Schildberg, Daniel Kuetting, Ulrike I Attenberger, Zeinab Abdullah, Alexander M C Böhner

  • The role of immune modulators in age-related macular degeneration.

    Survey of ophthalmology

    Authors: Lukas Schloesser, Sara M Klose, Matthias M Mauschitz, Zeinab Abdullah, Robert P Finger

  • Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.

    Molecular metabolism

    Authors: Frederike J Graelmann, Fabian Gondorf, Yasmin Majlesain, Birte Niemann, Katarina Klepac, Dominic Gosejacob, Marlene Gottschalk, Michelle Mayer, Irina Iriady, Philip Hatzfeld, Sophie K Lindenberg, Klaus Wunderling, Christoph Thiele, Zeinab Abdullah, Wei He, Karsten Hiller, Kristian Händler, Marc D Beyer, Thomas Ulas, Alexander Pfeifer, Charlotte Esser, Heike Weighardt, Irmgard Förster, Laia Reverte-Salisa