Skip to main content
News Icon

Publication

Immune memory characteristics of innate lymphoid cells

Immune memory characteristics of innate lymphoid cells -A Review

Immunological memory is an evolutionally acquired trait that allows a more robust response of an organism to re-infection. Two types of immune memory have been characterized: adaptive immune memory that is antigen-specific and is generated by adaptive immune cells, and trained immunity that is unspecific and developed by innate immune cells such as macrophages. This clear dichotomy fades when it comes to the immune cell compartment that shares characteristics of both: innate and adaptive immunity such as natural killer cells, innate lymphoid cells or gd T cells. In this review we describe what has been revealed so far about memory characteristics of innate-like immune cells that bridge the two types of immune response. We try to answer a still intriguing question: what kind of immune memory do innate-like cells develop?


Publication

https://www.immunosensation.de/research/publications/pubmed/immune-memory-characteristics-of-innate-lymphoid-cells.html


Contact

Prof. Mihai Netea

LIMES Institute

Related news

Neurons - generated through the differentiation of induced neural stem cells (iNSCs) derived from blood.

Publication

Researchers Transform Old Blood Cells into Young Brain Cells

—Researchers from the University Hospital of Bonn and the University of Bonn have succeeded in dramatically rejuvenating human cells in a test tube. To do so, they directly reprogrammed red blood cell precursors into stem cells from which neurons can be derived. During this process, the molecular clocks that indicate a cell’s age were reset. For example, blood cells from an 80-year-old were transformed into stem cells with a molecular age of less than 20 years. The results have been published in the journal Aging Cell.
View entry
Dr. Robert Hüneburg, Dr. Anne-Sophie Layritz, and Nicola Reents (from left) - conducted a survey and found that fewer than one in ten people with Lynch syndrome take Acetylsalicylic acid for cancer prevention – despite a high level of openness to new preventive approaches.

Publication

Aspirin Rarely Used for Colorectal Cancer Prevention

—According to international studies, taking Acetylsalicylic acid daily can protect people with Lynch syndrome from developing colorectal cancer – even at low doses. Researchers from the University Hospital Bonn (UKB), the University of Bonn, and the Center for Integrated Oncology (CIO) Bonn, in collaboration with the self-help organization SemiColon, have now found that these scientific findings have so far been insufficiently incorporated into clinical practice. The results of the LYNX study have now been published as a letter in the journal The Lancet Gastroenterology & Hepatology.
View entry
Smartphone-based retinal imaging in clinical practice in India: - The image was taken during a collaborative project between University Hospital Bonn (UKB) and Sankara Eye Foundation India on smartphone-based telemedical screening for diabetic retinopathy.

Publication

Smartphones as Retinal Cameras: New Opportunities for Global Eye Care

—Smartphones could play an important role in the early detection of eye diseases, including in settings where specialized ophthalmic infrastructure is limited. An international team of experts led by the UKB and the University of Bonn has comprehensively reviewed the current global landscape of smartphone-based fundus imaging. The researchers highlight the technical and clinical possibilities that already exist today, identify the limitations of these methods, and outline the conditions that must be met so that smartphone-based retinal imaging can be more widely integrated into screening.
View entry

Back to the news overview