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featured publications

  • UNC93B1 variants underlie TLR7-dependent autoimmunity.

    Science immunology

    Authors: Christine Wolf, Ee Lyn Lim, Mohammad Mokhtari, Barbara Kind, Alexandru Odainic, Eusebia Lara-Villacanas, Sarah Koss, Simon Mages, Katharina Menzel, Kerstin Engel, Gregor Dückers, Benedikt Bernbeck, Dominik T Schneider, Kathrin Siepermann, Tim Niehues, Carl Christoph Goetzke, Pawel Durek, Kirsten Minden, Thomas Dörner, Anna Stittrich, Franziska Szelinski, Gabriela Maria Guerra, Mona Massoud, Markus Bieringer, Carina C de Oliveira Mann, Eduardo Beltrán, Tilmann Kallinich, Mir-Farzin Mashreghi, Susanne V Schmidt, Eicke Latz, Johanna Klughammer, Olivia Majer, Min Ae Lee-Kirsch

  • Intermediate monocytes are associated with the first major adverse cardiovascular event in patients with stable coronary artery disease.

    International journal of cardiology

    Authors: Mihaela I Dregoesc, Adrian B Țigu, Siroon Bekkering, Charlotte D C C van der Heijden, Laura Rodwell, Sorana D Bolboacă, Leo A B Joosten, Mihai G Netea, Niels P Riksen, Adrian C Iancu

  • A Systematic Evaluation of Machine Learning-Based Biomarkers for Major Depressive Disorder.

    JAMA psychiatry

    Authors: Nils R Winter, Julian Blanke, Ramona Leenings, Jan Ernsting, Lukas Fisch, Kelvin Sarink, Carlotta Barkhau, Daniel Emden, Katharina Thiel, Kira Flinkenflügel, Alexandra Winter, Janik Goltermann, Susanne Meinert, Katharina Dohm, Jonathan Repple, Marius Gruber, Elisabeth J Leehr, Nils Opel, Dominik Grotegerd, Ronny Redlich, Robert Nitsch, Jochen Bauer, Walter Heindel, Joachim Gross, Benjamin Risse, Till F M Andlauer, Andreas J Forstner, Markus M Nöthen, Marcella Rietschel, Stefan G Hofmann, Julia-Katharina Pfarr, Lea Teutenberg, Paula Usemann, Florian Thomas-Odenthal, Adrian Wroblewski, Katharina Brosch, Frederike Stein, Andreas Jansen, Hamidreza Jamalabadi, Nina Alexander, Benjamin Straube, Igor Nenadic, Tilo Kircher, Udo Dannlowski, Tim Hahn

  • Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline.

    Alzheimer's & dementia (Amsterdam, Netherlands)

    Authors: Stefan J Teipel, Martin Dyrba, Luca Kleineidam, Frederic Brosseron, Fedor Levin, Davide Bruno, Katharina Buerger, Nicoleta Cosma, Luisa-Sophie Schneider, Emrah Düzel, Wenzel Glanz, Klaus Fliessbach, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Matthias H Munk, Franziska Maier, Oliver Peters, Nunzio Pomara, Robert Perneczky, Boris-Stephan Rauchmann, Josef Priller, Alfredo Ramirez, Nina Roy, Anja Schneider, Annika Spottke, Eike J Spruth, Sandra Roeske, Michael Wagner, Jens Wiltfang, Steffen Wolfsgruber, Claudia Bartels, Frank Jessen, Michael T Heneka

  • Efficacy and safety of fexinidazole for treatment of chronic indeterminate Chagas disease (FEXI-12): a multicentre, randomised, double-blind, phase 2 trial.

    The Lancet. Infectious diseases

    Authors: Maria-Jesus Pinazo, Colin Forsyth, Irene Losada, Elena Trigo Esteban, Magdalena García-Rodríguez, Maria Luz Villegas, Israel Molina, Clara Crespillo-Andújar, Montserrat Gállego, Cristina Ballart, Juan Carlos Ramirez, Tilman Aden, Achim Hoerauf, Kenneth Pfarr, Michel Vaillant, Tayná Marques, Jayme Fernandes, Bethania Blum, Isabela Ribeiro, Sergio Sosa-Estani, Fabiana Barreira, Joaquim Gascón

  • Efficacy and Safety of Methotrexate in Psoriasis Vulgaris Long-Term Treatment: A Real-World Observation Study.

    Indian journal of dermatology

    Authors: Dagmar Wilsmann-Theis, Rhena Funk, Rotraut Mössner, Thomas Bieber, Jörg Wenzel

  • EPAC1 enhances brown fat growth and beige adipogenesis.

    Nature cell biology

    Authors: Laia Reverte-Salisa, Sana Siddig, Staffan Hildebrand, Xi Yao, Jelena Zurkovic, Michelle Y Jaeckstein, Joerg Heeren, Frank Lezoualc'h, Natalie Krahmer, Alexander Pfeifer

  • Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts.

    Histopathology

    Authors: Veronika Bahlinger, Annalena Branz, Pamela L Strissel, Reiner Strick, Fabienne Lange, Carol I Geppert, Niklas Klümper, Michael Hölzel, Sven Wach, Helge Taubert, Danijel Sikic, Bernd Wullich, Miriam Angeloni, Fulvia Ferrazzi, Lauri Diehl, Maria Kovalenko, Emon Elboudwarej, Juliane M Jürgensmeier, Arndt Hartmann, Markus Eckstein

  • Inflammasomes in neurological disorders - mechanisms and therapeutic potential.

    Nature reviews. Neurology

    Authors: Kishore Aravind Ravichandran, Michael T Heneka

  • CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates lipogenesis in adipose tissue.

    Frontiers in immunology

    Authors: Michelle Y Jaeckstein, Isabell Schulze, Michael Wolfgang Zajac, Markus Heine, Oliver Mann, Alexander Pfeifer, Joerg Heeren