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featured publications

  • Molecular characterization of FAM222B as a novel disease gene for dominant cardiovascular laterality defects.

    Scientific reports

    Authors: Nina Reitz, Jessica Lambertz, Öznur Yilmaz, Tobias T Lindenberg, Khadija Channab, Birgit Rau, Stefanie Ramrath, Enrico Mingardo, Hanna Schöpper, Bettina C Kirchmaier, Matthias Geyer, Gabriel C Dworschak, Johannes Breuer, Nicole Müller, Birthe Schaidinger, Alina C Hilger, Julia Hoefele, Korbinian M Riedhammer, Marc-Phillip Hitz, Gregor Dombrowsky, Hashim Abdul-Khaliq, Ulrike M M Bauer, Lars Fester, Heiko M Reutter, Katinka Breuer, Benjamin Odermatt

  • AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins.

    Nature communications

    Authors: Bianca Broske, Benjamin A McEnroe, Sophie C Frechen, Tim N Kempchen, Caroline I Fandrey, Elisabeth Tan, Dominic Ferber, Michelle C R Yong, Marie Kleinert, Julia M Messmer, Peter Konopka, Alexander Hoch, Katja Blumenstock, Jan M P Tödtmann, Johannes Oldenburg, Heiko Rühl, Alexander Semaan, Marieta I Toma, Kristina Markova, Sebastian Kobold, Tim Rollenske, Matthias Geyer, Stephan Menzel, Tobias Bald, Jonathan L Schmid-Burgk, Gregor Hagelueken, Michael Hölzel

  • Association of Pretransplant Neutrophil-to-Lymphocyte Ratio With Major Adverse Cardiovascular Events in Kidney Transplant Recipients With Normal C-Reactive Protein Levels.

    Transplantation proceedings

    Authors: Uta Sonja Scheidt, Carola Ellen Kleine, Dominik Bös, Roxana Werberich, Louisa Werberich, Stephan Reinhard, Sibylle von Vietinghoff, Rainer Peter Woitas, Sebastian Schwab

  • metadeconfoundR: Covariate analysis of high-dimensional cross-sectional omics data.

    Bioinformatics advances

    Authors: Till Birkner, Chia-Yu Chen, Morgan Essex, Kilian Dahm, Ulrike Löber, Thomas Ulas, Víctor Hugo Jarquín-Díaz, Sofia Kirke Forslund-Startceva

  • [Value of Clinical Video Registries for Research and Teaching in Minimally Invasive and Robotic Surgery].

    Zentralblatt fur Chirurgie

    Authors: Philipp Feodorovici, Lena Krings, Joachim Schmidt, Jörg C Kalff, Jan Arensmeyer, Hanno Matthaei

  • Loss of type I interferon signaling in Kupffer cells triggers viral spread and fatal liver damage in a mouse model of Crimean-Congo hemorrhagic fever.

    PLoS pathogens

    Authors: Shintaro Yamada, Masayuki Shimojima, Takeshi Saito, Junki Maruyama, Hiroki Kato

  • A four-dimensional framework for classifying functional states in immune cells.

    iScience

    Authors: Rachel Brandes-Leibovitz, Gal Yankovitz, Eran Bacharach, Mihai G Netea, Evangelos J Giamarellos-Bourboulis, Irit Gat-Viks

  • Cuticular Drusen and the Risk of Progression to Late Age-Related Macular Degeneration: A MACUSTAR Study Report.

    Ophthalmology science

    Authors: Lourdes Vidal-Oliver, Jan Terheyden, Charlotte Behning, Vanessa Basten, Maria Kornau, Lukas Schlößer, Ulrich F O Luhmann, Klaus Peter Moll, Nadia Zakaria, Sergio Leal, Matthias Schmid, Steffen Schmitz Valckenberg, Frank Holz, Robert P Finger, Marlene Saßmannshausen

  • Microglia activation by derepression of endogenous retroviruses drives inflammation and cellular senescence.

    Nature neuroscience

    Authors: Xin Yan, Christina Georgopoulou, Hang-Mao Lee, Ala Ahrari, Jenny Russ, Vijay Chandrasekar, Tim Ducksch, Giuliano Crispatzu, Valentina Talevi, Liang Qiao, Shobhit Agrawal, Sophie Crux, Andrew W Daman, Lena Wischhof, Miriam Stork, Margit Zweyer, Emma Dorotea Zanfi, Manon Chevallot-Beroux, Yunxiao Li, Elena De-Domenico, Dina Hüsson, Lorenzo Bonaguro, Yuanfang Li, Jonas Schulte-Schrepping, Qingyi Liang, Ketty Kessler, Dan Ehninger, Shahin Rafii, Jiankai Luo, Andreas Hermann, Annett Halle, Ying Liu, Elvira Mass, Melania Capasso, Hiroki Kato, Joachim L Schultze, Pierluigi Nicotera, Daniele Bano, Steven Zvi Josefowicz, Martin Fuhrmann, Thomas Ulas, Marc Beyer, Juntang Lin, Monique M B Breteler, N Ahmad Aziz, Paolo Salomoni

  • Author Correction: Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.

    Nature

    Authors: Andrea Ablasser, Jonathan L Schmid-Burgk, Inga Hemmerling, Gabor L Horvath, Tobias Schmidt, Eicke Latz, Veit Hornung