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featured publications

  • Gastrointestinal Pathogens in Multi-Infected Individuals: A Cluster Analysis of Interaction.

    Microorganisms

    Authors: Joy Backhaus, Hagen Frickmann, Ralf Matthias Hagen, Gustavo Concha, Ernst Molitor, Achim Hoerauf, Simone Kann

  • Identification and comparison of sex-specific serious adverse drug reactions in spontaneous reports and systematically collected reports (ADRED).

    British journal of clinical pharmacology

    Authors: Patrick Christ, Diana Dubrall, Katja Susanne Just, Britta Lewke, Maike Below, Julia Carolin Stingl, Matthias Schmid, Bernhardt Sachs

  • Reconstructing disease dynamics for mechanistic insights and clinical benefit.

    Nature communications

    Authors: Amit Frishberg, Neta Milman, Ayelet Alpert, Hannah Spitzer, Ben Asani, Johannes B Schiefelbein, Evgeny Bakin, Karen Regev-Berman, Siegfried G Priglinger, Joachim L Schultze, Fabian J Theis, Shai S Shen-Orr

  • The global burden of antimicrobial resistance - urinary tract infections.

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    Authors: Sibylle Von Vietinghoff, Olga Shevchuk, Ulrich Dobrindt, Daniel Robert Engel, Selina K Jorch, Christian Kurts, Thomas Miethke, Florian Wagenlehner

  • Insights into the molecular basis and mechanism of heme-triggered TLR4 signalling: The role of heme-binding motifs in TLR4 and MD2.

    Immunology

    Authors: Marie-T Hopp, Janine Holze, Felicitas Lauber, Laura Holtkamp, Dhruv C Rathod, Maria A Miteva, Elisa B Prestes, Matthias Geyer, Bénédicte Manoury, Nicolas S Merle, Lubka T Roumenina, Marcelo T Bozza, Günther Weindl, Diana Imhof

  • β1 integrin signaling governs necroptosis via the chromatin-remodeling factor CHD4.

    Cell reports

    Authors: Zhiqi Sun, Filippo M Cernilogar, Helena Horvatic, Assa Yeroslaviz, Zeinab Abdullah, Gunnar Schotta, Veit Hornung

  • Interim analyses of the multinational real-world prospective cohort HEM-POWR study evaluating the effectiveness and safety of damoctocog alfa pegol in patients with hemophilia A.

    European journal of haematology

    Authors: Mark T Reding, María Teresa Álvarez-Román, Giancarlo Castaman, Maissaa Janbain, Tadashi Matsushita, Karina Meijer, Kathrin Schmidt, Johannes Oldenburg

  • Hemophagocytic lymphohistiocytosis-how common and how severe is it as a complication of malaria? Retrospective case series and review of the literature.

    Infection

    Authors: Hans Martin Orth, Dorothea Wiemer, Sophie Schneitler, Andreas Schönfeld, Martha Charlotte Holtfreter, Smaranda Gliga, Andre Fuchs, Frieder Pfäfflin, Claudia Maria Denkinger, Sven Kalbitz, Carlos Fritzsche, Marc P Hübner, Janina Trauth, Björn-Erik Ole Jensen, Tom Luedde, Torsten Feldt

  • The telomerase inhibitor imetelstat differentially targets JAK2V617F versus CALR mutant myeloproliferative neoplasm cells and inhibits JAK-STAT signaling.

    Frontiers in oncology

    Authors: Kathrin Olschok, Bianca Altenburg, Marcelo A S de Toledo, Angela Maurer, Anne Abels, Fabian Beier, Deniz Gezer, Susanne Isfort, Katrin Paeschke, Tim H Brümmendorf, Martin Zenke, Nicolas Chatain, Steffen Koschmieder

  • Top publication

    UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence.

    Nature communications

    Authors: Alessio De Magis, Michaela Limmer, Venkat Mudiyam, David Monchaud, Stefan Juranek, Katrin Paeschke