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  • Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment.

    Science translational medicine

    Authors: Lara Lechner, Robert Opitz, Matt J Silver, Philipp M Krabusch, Andrew M Prentice, Martha S Field, Harald Stachelscheid, Elsa Leitão, Christopher Schröder, Valeria Fernandez Vallone, Bernhard Horsthemke, Karl-Heinz Jöckel, Börge Schmidt, Markus M Nöthen, Per Hoffmann, Stefan Herms, Patrick W Kleyn, Matthias Megges, Ulrike Blume-Peytavi, Katja Weiss, Knut Mai, Oliver Blankenstein, Benedikt Obermayer, Susanna Wiegand, Peter Kühnen

  • Catecholamines and inflammation in advanced liver disease: more closely intertwined than expected?

    Gut

    Authors: Hans Dieter Nischalke, Christina Nischalke, Franziska Schmalz, Christine Möller, Benjamin Krämer, Alexandra Funken, Adrian Goldspink, Jacob Nattermann, Christian Strassburg, Philipp Lutz

  • Secretomics reveals gelatinase substrates at the blood-brain barrier that are implicated in astroglial barrier function.

    Science advances

    Authors: Miriam Burmeister, Annika Fraunenstein, Martin Kahms, Laura Arends, Hanna Gerwien, Tushar Deshpande, Tanja Kuhlmann, Catharina C Gross, Venu N Naik, Heinz Wiendl, Juergen Klingauf, Felix Meissner, Lydia Sorokin

  • Dendritic cell type 3 arises from Ly6C monocyte-dendritic cell progenitors.

    Immunity

    Authors: Zhaoyuan Liu, Haiting Wang, Ziyi Li, Regine J Dress, Yiwen Zhu, Shuangyan Zhang, Donatella De Feo, Wan Ting Kong, Peiliang Cai, Amanda Shin, Cécile Piot, Jiangyan Yu, Yaqi Gu, Mingnan Zhang, Caixia Gao, Lei Chen, Honglin Wang, Mathias Vétillard, Pierre Guermonprez, Immanuel Kwok, Lai Guan Ng, Svetoslav Chakarov, Andreas Schlitzer, Burkhard Becher, Charles-Antoine Dutertre, Bing Su, Florent Ginhoux

  • TLR7/8 stress response drives histiocytosis in SLC29A3 disorders.

    The Journal of experimental medicine

    Authors: Takuma Shibata, Ryota Sato, Masato Taoka, Shin-Ichiroh Saitoh, Mayumi Komine, Kiyoshi Yamaguchi, Susumu Goyama, Yuji Motoi, Jiro Kitaura, Kumi Izawa, Yoshio Yamauchi, Yumiko Tsukamoto, Takeshi Ichinohe, Etsuko Fujita, Ryosuke Hiranuma, Ryutaro Fukui, Yoichi Furukawa, Toshio Kitamura, Toshiyuki Takai, Arinobu Tojo, Mamitaro Ohtsuki, Umeharu Ohto, Toshiyuki Shimizu, Manabu Ozawa, Nobuaki Yoshida, Toshiaki Isobe, Eicke Latz, Kojiro Mukai, Tomohiko Taguchi, Hiroaki Hemmi, Shizuo Akira, Kensuke Miyake

  • Dose Recommendations for Common Drugs in Patients with Liver Cirrhosis: A Systematic Literature Review.

    Clinical drug investigation

    Authors: Katharina Karsten Dafonte, Lisa Weber, Florian Chmielewski, Anna Maria Böhmer, Philipp Lutz, Gunther Hartmann, Ulrich Jaehde, Martin Coenen

  • Safety and efficacy of amlitelimab, a fully human, non-depleting, non-cytotoxic anti-OX40Ligand monoclonal antibody, in atopic dermatitis: results of a phase IIa randomised placebo-controlled trial.

    The British journal of dermatology

    Authors: Stephan Weidinger, Thomas Bieber, Michael J Cork, Adam Reich, Rosamund Wilson, Sonia Quaratino, Marisa Stebegg, Nuala Brennan, Sally Gilbert, John T O'Malley, Ben Porter-Brown

  • A Worldwide Analysis of Adipose-Derived Stem Cells and Stromal Vascular Fraction in Orthopedics: Current Evidence and Applications.

    Journal of clinical medicine

    Authors: Robert Ossendorff, Alessandra Menon, Frank A Schildberg, Pietro S Randelli, Sebastian Scheidt, Christof Burger, Dieter C Wirtz, Davide Cucchi

  • Gallium-68 labelled RGD PET/CT imaging of endothelial activation in COVID-19 patients.

    Scientific reports

    Authors: Evelien A J van Genugten, Theresa J van Lith, Frederik M A van den Heuvel, Josee L van Steenis, Romy M Ten Heggeler, Monique Brink, Laura Rodwell, Frederick J A Meijer, Daphne Lobeek, Wanda Hagmolen Of Ten Have, Frank L van de Veerdonk, Mihai G Netea, Mathias Prokop, Robin Nijveldt, Anil M Tuladhar, Erik H J G Aarntzen

  • Independent and additive contribution of white matter hyperintensities and Alzheimer's disease pathology to basal forebrain cholinergic system degeneration.

    NeuroImage. Clinical

    Authors: Christine Kindler, Neeraj Upadhyay, Zeynep Bendella, Franziska Dorn, Vera C Keil, Gabor C Petzold