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  • A Systematic Evaluation of Machine Learning-Based Biomarkers for Major Depressive Disorder.

    JAMA psychiatry

    Authors: Nils R Winter, Julian Blanke, Ramona Leenings, Jan Ernsting, Lukas Fisch, Kelvin Sarink, Carlotta Barkhau, Daniel Emden, Katharina Thiel, Kira Flinkenflügel, Alexandra Winter, Janik Goltermann, Susanne Meinert, Katharina Dohm, Jonathan Repple, Marius Gruber, Elisabeth J Leehr, Nils Opel, Dominik Grotegerd, Ronny Redlich, Robert Nitsch, Jochen Bauer, Walter Heindel, Joachim Gross, Benjamin Risse, Till F M Andlauer, Andreas J Forstner, Markus M Nöthen, Marcella Rietschel, Stefan G Hofmann, Julia-Katharina Pfarr, Lea Teutenberg, Paula Usemann, Florian Thomas-Odenthal, Adrian Wroblewski, Katharina Brosch, Frederike Stein, Andreas Jansen, Hamidreza Jamalabadi, Nina Alexander, Benjamin Straube, Igor Nenadic, Tilo Kircher, Udo Dannlowski, Tim Hahn

  • Efficacy and safety of fexinidazole for treatment of chronic indeterminate Chagas disease (FEXI-12): a multicentre, randomised, double-blind, phase 2 trial.

    The Lancet. Infectious diseases

    Authors: Maria-Jesus Pinazo, Colin Forsyth, Irene Losada, Elena Trigo Esteban, Magdalena García-Rodríguez, Maria Luz Villegas, Israel Molina, Clara Crespillo-Andújar, Montserrat Gállego, Cristina Ballart, Juan Carlos Ramirez, Tilman Aden, Achim Hoerauf, Kenneth Pfarr, Michel Vaillant, Tayná Marques, Jayme Fernandes, Bethania Blum, Isabela Ribeiro, Sergio Sosa-Estani, Fabiana Barreira, Joaquim Gascón

  • CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates lipogenesis in adipose tissue.

    Frontiers in immunology

    Authors: Michelle Y Jaeckstein, Isabell Schulze, Michael Wolfgang Zajac, Markus Heine, Oliver Mann, Alexander Pfeifer, Joerg Heeren

  • Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.

    Immunity

    Authors: Simone J C F M Moorlag, Lukas Folkman, Rob Ter Horst, Thomas Krausgruber, Daniele Barreca, Linda C Schuster, Victoria Fife, Vasiliki Matzaraki, Wenchao Li, Stephan Reichl, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Helga Dijkstra, Heidi Lemmers, Bram van Cranenbroek, Esther van Rijssen, Hans J P M Koenen, Irma Joosten, Cheng-Jian Xu, Yang Li, Leo A B Joosten, Reinout van Crevel, Mihai G Netea, Christoph Bock

  • Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts.

    Histopathology

    Authors: Veronika Bahlinger, Annalena Branz, Pamela L Strissel, Reiner Strick, Fabienne Lange, Carol I Geppert, Niklas Klümper, Michael Hölzel, Sven Wach, Helge Taubert, Danijel Sikic, Bernd Wullich, Miriam Angeloni, Fulvia Ferrazzi, Lauri Diehl, Maria Kovalenko, Emon Elboudwarej, Juliane M Jürgensmeier, Arndt Hartmann, Markus Eckstein

  • Inflammasomes in neurological disorders - mechanisms and therapeutic potential.

    Nature reviews. Neurology

    Authors: Kishore Aravind Ravichandran, Michael T Heneka

  • EPAC1 enhances brown fat growth and beige adipogenesis.

    Nature cell biology

    Authors: Laia Reverte-Salisa, Sana Siddig, Staffan Hildebrand, Xi Yao, Jelena Zurkovic, Michelle Y Jaeckstein, Joerg Heeren, Frank Lezoualc'h, Natalie Krahmer, Alexander Pfeifer

  • Efficacy and Safety of Methotrexate in Psoriasis Vulgaris Long-Term Treatment: A Real-World Observation Study.

    Indian journal of dermatology

    Authors: Dagmar Wilsmann-Theis, Rhena Funk, Rotraut Mössner, Thomas Bieber, Jörg Wenzel

  • Treatment of atopic dermatitis: Recently approved drugs and advanced clinical development programs.

    Allergy

    Authors: Svenja Müller, Laura Maintz, Thomas Bieber

  • Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP.

    Nature communications

    Authors: Martin F Peter, Jan A Ruland, Yeojin Kim, Philipp Hendricks, Niels Schneberger, Jan Peter Siebrasse, Gavin H Thomas, Ulrich Kubitscheck, Gregor Hagelueken