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  • Poxvirus dsDNA genomes differentially activate AIM2 or NLRP3 inflammasomes in human primary cells.

    The EMBO journal

    Authors: Yonas M Tesfamariam, Maria H Christensen, Stefan Diehl, Tabea Klein, Julius M Lingnau, Sabine Normann, Elena Hagelauer, Miriam Herbert, Sophie Reimer, Richa P Joshi, Pujan Engels, Steffen Pritzl, Pietro Fontana, Thomas Zillinger, Gunther Hartmann, Anna Eis-Hübinger, Martin C Lam, Klaus J Walgenbach, Felix Meissner, Hao Wu, Florian I Schmidt

  • Sodium glucose transporter 2 inhibition maintains kidney antibacterial response by decreasing complement C1q.

    Kidney international

    Authors: Georg W Sendtner, Julia Miranda, Pia Naumann, Maximilian Weiss, Pelin Güls, Ernst Molitor, Uta Scheidt, Axel Schmidt, Kerstin U Ludwig, Annika Hilger, Ulrich Dobrindt, Thomas Mayrhofer, Christian Kurts, Florian Wagenlehner, Olga Shevshuk, Sibylle von Vietinghoff

  • Integrated transcriptomic and proteomic profiling identifies an interferon-dependent inflammatory endotype in sepsis.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    Authors: Andrian Fratea, Anca-Lelia Riza, Florentina Dumitrescu, Stefania Dorobantu, Andrei Pirvu, Adina Dragos, Andra Grigorescu, Ioana Streata, Mihai G Netea, Vinod Kumar, Collins K Boahen

  • On Factor VIII Assay Discrepancies in Post-infusion Samples Obtained from Patients Treated with Efanesoctocog Alfa.

    Hamostaseologie

    Authors: Jens Müller, Martin Büchsel, Behnaz Pezeshkpoor, Heiko Rühl, Bernd Pötzsch, Claudia Klein, Georg Goldmann, Natascha Marquardt, Thilo Albert, Kerstin Herbst, Johannes Oldenburg

  • Antibiotic-Mediated Modulation of the Gut Microbiome Identifies Taurine as a Modulator of Adipocyte Function Through TGR5 Signaling.

    International journal of molecular sciences

    Authors: Elisabeth Jäger, Viktoriya Peeva, Thorsten Gnad, Sven-Bastiaan Haange, Ulrike Rolle-Kampczyk, Claudia Stäubert, Petra Krumbholz, John T Heiker, Claudia Gebhardt, Ute Krügel, Paromita Sen, Monika Harazin, Viktoria Stab, Julia Münzker, Nazha Hamdani, Alexander Pfeifer, Martin von Bergen, Andreas Till, Wiebke K Fenske

  • Helminth Antigens Modulate Virus-Induced Activation of CD154 (CD40L) Expression on T Cells in -Infected Individuals.

    Pathogens (Basel, Switzerland)

    Authors: Brice Armel Nembot Fogang, Kathrin Arndts, Tomabu Adjobimey, Michael Owusu, Vera Serwaa Opoku, Derrick Adu Mensah, John Boateng, Jubin Osei-Mensah, Julia Meyer, Ute Klarmann-Schulz, Sacha Horn, Inge Kroidl, Alexander Y Debrah, Achim Hoerauf, Manuel Ritter, Linda B Debrah

  • Cytokine storm.

    Nature reviews. Disease primers

    Authors: Rajendra Karki, Mihai G Netea, Caroline Diorio, Thirumala-Devi Kanneganti

  • Structure-Activity and Structure-Degradation Relationship Studies of 2-Amino-6-(benzimidazol-2-ylmethyl)-N9-heteroarylpurines as Potent and Selective CDK12/13 Inhibitors and Cyclin K Degraders.

    Journal of medicinal chemistry

    Authors: Thiyagamurthy Pandurangan, Solomon Tadesse Zeleke, Anna Iermolaieva, Pompom Ghosh, John Mosior, Luxin Sun, Dylan Grassie, Maximilian Schmitz, Mahalakshmi Naidu Kalaga, William Albritton, Manuel Manzanares Rodas, Sean Chin Chan, Sylvia Frydman, Samer Sansil, Matthias Geyer, Ernst Schönbrunn, William R Roush, Derek R Duckett, Andrii Monastyrskyi

  • Cholesterol-lowering effects of oats induced by microbially produced phenolic metabolites in metabolic syndrome: a randomized controlled trial.

    Nature communications

    Authors: Linda Klümpen, Aakash Mantri, Maren Philipps, Waldemar Seel, Laura Schlautmann, Mohamed H Yaghmour, Verena Wiemann, Birgit Stoffel-Wagner, Martin Coenen, Leonie Weinhold, Jan Hasenauer, Thomas Fließwasser, Sven Burgdorf, Christoph Thiele, Peter Stehle, Marie-Christine Simon

  • A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.

    Nature immunology

    Authors: Saumya Kumar, Chaofan Li, Liang Zhou, Qiuyao Zhan, Ahmed Alaswad, Sonja Volland, Bibiana Costa, Simon Alexander Krooss, Isabel Klefenz, Hagen Schmaus, Antonia Zeuzem, Dorothee von Witzendorff, Helena Lickei, Lea Pueschel, Anke R M Kraft, Markus Cornberg, Andreas Rembert Koczulla, Isabell Pink, Marius M Hoeper, Cheng-Jian Xu, Susanne Häussler, Miriam Wiestler, Mihai G Netea, Thomas Illig, Jie Sun, Yang Li