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featured publications

  • Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML.

    Cell reports. Medicine

    Authors: Ben Haladik, Margarita Maurer-Granofszky, Peter Zoescher, Raul Jimenez-Heredia, Alexandra Frohne, Anna Segarra-Roca, Chloe Casey, Felix Kartnig, Sarah Giuliani, Christina Rashkova, Peter Repiscak, Michael N Dworzak, Giulio Superti-Furga, Kaan Boztug

  • A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation.

    Molecular cell

    Authors: Jennifer R Devlin, Ben Martin, Nenad Bartonicek, Keziah Ting, Zheng Fan, Izabela Todorovski, Filip Bjelosevic, Sandra Verschoor, Annette Ciccone, Joseph A Trapani, Attila Horvath, Emily Tinsley, Peter Fraser, Andrea Newbold, Jarrod J Sandow, Andrea Muscat, Kaylene J Simpson, Matthias Geyer, Stephin J Vervoort, Ricky W Johnstone

  • A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers.

    Frontiers in immunology

    Authors: Antonio José Cabrera-Serrano, Lucía Ruiz-Durán, Juan Francisco Gutiérrez-Bautista, María Carretero-Fernández, Rob Ter Horst, Yang Li, Fernando Jesús Reyes-Zurita, Francisco José García-Verdejo, Mihai G Netea, Pedro Sánchez-Rovira, Miguel Ángel López-Nevot, Antonio Sampedro, Juan Sainz

  • The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets.

    Nature immunology

    Authors: Alexander N R Weber, Róisín M McManus, Veit Hornung, Matthias Geyer, Jasmin B Kuemmerle-Deschner, Eicke Latz

  • [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].

    Medizinische Klinik, Intensivmedizin und Notfallmedizin

    Authors: Frank M Brunkhorst, Michael Adamzik, Hubertus Axer, Michael Bauer, Christian Bode, Hans-Georg Bone, Thorsten Brenner, Michael Bucher, Sascha David, Maximilian Dietrich, Christian Eckmann, Gunnar Elke, Torben Esser, Thomas Felbinger, Christine Geffers, Herwig Gerlach, Béatrice Grabein, Matthias Gründling, Ulf Günther, Stefan Hagel, Andreas Hecker, Stefan Henkel, Babila Janusan, Stefan John, Achim Jörres, Achim Kaasch, Stefan Kluge, Matthias Kochanek, Agnieszka Lajca, Gernot Marx, Konstantin Mayer, Patrick Meybohm, Onnen Mörer, Michael Oppert, Vladimir Patchev, Mathias Pletz, Christian Putensen, Tim Rahmel, Jenny Rosendahl, Rolf Rossaint, Bernd Salzberger, Michael Sander, Stefan Schaller, Christina Scharf-Janssen, Felix Schmitt, Matthias Unterberg, Markus Weigand, Arved Weimann, Sebastian Weis, Björn Weiß, Alexander Wolf, Alexander Zarbock

  • Plain language summary of publication of the 48-week results from the PULSAR study investigating how well a new dose of aflibercept works and how safe it is for people with wet age-related macular degeneration.

    Therapeutic advances in ophthalmology

    Authors: Paolo Lanzetta, Jean-François Korobelnik, Jeffrey S Heier, Sergio Leal, Frank G Holz, William Lloyd Clark, David Eichenbaum, Tomohiro Iida, Xiaodong Sun, Alyson J Berliner, Andrea Schulze, Thomas Schmelter, Ursula Schmidt-Ott, Xin Zhang, Robert Vitti, Karen W Chu, Kimberly Reed, Rohini Rao, Rafia Bhore, Yenchieh Cheng, Tien Y Wong

  • Effects of simulated Martian environmental stressors on specific human pathogen-immune system interactions.

    mBio

    Authors: Tommaso Zaccaria, Özlem Bulut, Anaisa V Ferreira, Margo Dona, Jeroen D Langereis, Rob J Mesman, Joppe Wesseling, Laura van Niftrik, Mihai G Netea, Petra Rettberg, Kristina Beblo-Vranesevic, Marien I de Jonge, Jorge Domínguez-Andrés

  • Mechanistic in vivo studies of secondary skin-to-skin peanut allergen transfer to determine the impact of hand washing in reducing the risk of cutaneous sensitization.

    The British journal of dermatology

    Authors: Constanze Baber, Loris Busch, Anna Lena Klein, Victor Hugo Pacagnelli Infante, Sumayah Abdul-Jabbar, Faiza Benaouda, Preeti Khurana, Stuart A Jones, Natalija Novak, Alexandra F Santos, Carsten Flohr, Martina C Meinke, Silke B Lohan

  • Clinical outcomes of the EyeWatch system: three-year results.

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

    Authors: Constance Liegl, Sarah Hundertmark, Frank G Holz, Karl Mercieca

  • Genome-wide association study of borderline personality disorder identifies 11 loci and highlights shared risk with mental and somatic disorders.

    medRxiv : the preprint server for health sciences

    Authors: Fabian Streit, Swapnil Awasthi, Alisha Sm Hall, Alice Braun, Maria Niarchou, Eirini Marouli, Oladapo Babajide, Josef Frank, Lea Zillich, Carolin M Callies, Diana Avetyan, Eric Zillich, Joonas Naamanka, Jean Gonzalez, Arvid Harder, Yi Lu, Zouhair Aherrahrou, Zain-Ul-Abideen Ahmad, Helga Ask, Anthony Batzler, Michael E Benros, Odette M Brand-de Wilde, Søren Brunak, Mie T Bruun, Lea An Christoffersen, Lucía Colodro-Conde, Brandon J Coombes, Elizabeth C Corfield, Norbert Dahmen, Maria Didriksen, Khoa M Dinh, Srdjan Djurovic, Joseph Dowsett, Ole Kristian Drange, Helene Dukal, Susanne Edelmann, Christian Erikstrup, Mariana K Espinola, Eva Fassbinder, Annika Faucon, Diana S Ferreira de Sá, Jerome C Foo, Maria Gilles, Alfonso Gutiérrez-Zotes, Thomas F Hansen, Magnus Haraldsson, R Patrick Harper, Alexandra Havdahl, Urs Heilbronner, Stefan Herms, Henrik Hjalgrim, Christopher Hübel, Gitta A Jacob, Bitten Aagaard, Anders Jorgensen, Martin Jungkunz, Nikolaus Kleindienst, Nora Knoblich, Stefanie Koglin, Julia Kraft, Kristi Krebs, Christopher W Lee, Yuhao Lin, Stefanie Lis, Amanda Lisoway, Ioannis A Malogiannis, Amy Martinsen, Tolou Maslahati, Katharina Merz, Andreas Meyer-Lindenberg, Susan Mikkelsen, Christina Mikkelsen, Arian Mobascher, Gerard Muntané, Asmundur Oddsson, Sisse R Ostrowski, Teemu Palviainen, Ole Bv Pedersen, Geir Pedersen, Liam Quinn, Matthias A Reinhard, Florian A Ruths, Björn H Schott, Michael Schredl, Emanuel Schwarz, Cornelia E Schwarze, Michael Schwinn, Tabea Send, Engilbert Sigurdsson, Katja Simon-Keller, Astros T Skuladottir, Joaquim Soler, Anne Sonley, Erik Sørensen, Hreinn Stefansson, Peter Straub, Jaana Suvisaari, Martin Tesli, Jacob Træholt, Henrik Ullum, Maja P Völker, G Bragi Walters, Rujia Wang, Christian C Witt, Gerhard Zarbock, Peter Zill, John-Anker Zwart, Ole A Andreassen, Arnoud Arntz, Joanna M Biernacka, Martin Bohus, Gerome Breen, Alexander L Chapman, Sven Cichon, Lea K Davis, Michael Deuschle, Sebastian Euler, Sabine C Herpertz, Benjamin Hummelen, Andrea Jobst, Jaakko Kaprio, James L Kennedy, Kelli Lehto, Klaus Lieb, Lourdes Martorell, Shelley McMain, Richard Musil, Vanessa Nieratschker, Markus M Nöthen, Frank Padberg, Aarno Palotie, Juan C Pascual, Nader Perroud, Josep A Ramos-Quiroga, Ted Reichborn-Kjennerud, Marta Ribases, Stefan Roepke, Dan Rujescu, Sandra Sanchez-Roige, Claudia Schilling, Christian Schmahl, Kari Stefansson, Thorgeir E Thorgeirsson, Gustavo Turecki, Elisabet Vilella, Thomas Werge, Bendik S Winsvold, Johannes Wrege, Marcella Rietschel, Stephan Ripke, Stephanie H Witt