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featured publications

  • Clinical experience of switching patients with severe hemophilia to rVIII-SingleChain or rIX-FP.

    Current medical research and opinion

    Authors: Johannes Oldenburg, Steven W Pipe, Maria Elisa Mancuso, Robert Klamroth, Abel Hassoun, Martin Olivieri, Georg Goldmann, Gili Kenet, Wolfgang Miesbach, Jolana Schmiedl, Inga Hegemann

  • Microbiome-Related Indole and Serotonin Metabolites are Linked to Inflammation and Psychiatric Symptoms in People Living with HIV.

    International journal of tryptophan research : IJTR

    Authors: Nadira Vadaq, Yue Zhang, Elise Meeder, Lisa Van de Wijer, Muhammad Hussein Gasem, Leo Ab Joosten, Mihai G Netea, Quirijn de Mast, Vasiliki Matzaraki, Arnt Schellekens, Jingyuan Fu, André Jam van der Ven

  • Analysis of associations between dietary patterns, genetic disposition, and cognitive function in data from UK Biobank.

    European journal of nutrition

    Authors: Christina-Alexandra Schulz, Leonie Weinhold, Matthias Schmid, Markus M Nöthen, Ute Nöthlings

  • Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease.

    Genome medicine

    Authors: Neha Mishra, Konrad Aden, Johanna I Blase, Nathan Baran, Dora Bordoni, Florian Tran, Claudio Conrad, Diana Avalos, Charlot Jaeckel, Michael Scherer, Signe B Sørensen, Silja H Overgaard, Berenice Schulte, Susanna Nikolaus, Guillaume Rey, Gilles Gasparoni, Paul A Lyons, Joachim L Schultze, Jörn Walter, Vibeke Andersen, Emmanouil T Dermitzakis, Stefan Schreiber, Philip Rosenstiel

  • Identification of an Optimal TLR8 Ligand by Alternating the Position of 2'-O-Ribose Methylation.

    International journal of molecular sciences

    Authors: Marina Nicolai, Julia Steinberg, Hannah-Lena Obermann, Francisco Venegas Solis, Eva Bartok, Stefan Bauer, Stephanie Jung

  • SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA.

    Molecular cell

    Authors: Shovamayee Maharana, Stefanie Kretschmer, Susan Hunger, Xiao Yan, David Kuster, Sofia Traikov, Thomas Zillinger, Marc Gentzel, Shobha Elangovan, Padmanava Dasgupta, Nagaraja Chappidi, Nadja Lucas, Katharina Isabell Maser, Henrike Maatz, Alexander Rapp, Virginie Marchand, Young-Tae Chang, Yuri Motorin, Norbert Hubner, Gunther Hartmann, Anthony A Hyman, Simon Alberti, Min Ae Lee-Kirsch

  • A guide to systems-level immunomics.

    Nature immunology

    Authors: Lorenzo Bonaguro, Jonas Schulte-Schrepping, Thomas Ulas, Anna C Aschenbrenner, Marc Beyer, Joachim L Schultze

  • Corallopyronin A: antimicrobial discovery to preclinical development.

    Natural product reports

    Authors: Anna K Krome, Tim Becker, Stefan Kehraus, Andrea Schiefer, Michael Gütschow, Lillibeth Chaverra-Muñoz, Stephan Hüttel, Rolf Jansen, Marc Stadler, Alexandra Ehrens, Domen Pogorevc, Rolf Müller, Marc P Hübner, Thomas Hesterkamp, Kenneth Pfarr, Achim Hoerauf, Karl G Wagner, Gabriele M König

  • Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first-line intensified treatment of pediatric patients with high-risk acute lymphoblastic leukemia in CoALL08-09 trial.

    Pediatric blood & cancer

    Authors: Kerstin Mezger, Sabine Ebert, Hannah Elisa Muhle, Udo Zur Stadt, Arndt Borkhardt, Dagmar Dilloo, Jörg Faber, Tobias Feuchtinger, Thomas Imschweiler, Norbert Jorch, Arnulf Pekrun, Irene Schmid, Franziska Schramm, Martin Zimmermann, Martin A Horstmann, Gabriele Escherich

  • How location and cellular signaling combine to activate the NLRP3 inflammasome.

    Cellular & molecular immunology

    Authors: Anil Akbal, Alesja Dernst, Marta Lovotti, Matthew S J Mangan, Róisín M McManus, Eicke Latz