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featured publications

  • Comparative Performance of agentic AI and Physicians in Taking Clinical History across Leading Large Language Models (LLMs).

    medRxiv : the preprint server for health sciences

    Authors: Sophie Steinbuch, Luka de Vos-Hillebrand, Connor O'Neill-Dee, Iris Wu, Hannah Steinbuch, Zsófi Kulcsár, Avanish Ranjan, Ashish Verma, Jennifer Landsberg, Dimo Dietrich, Charles C Hardin, Rakesh K Jain, Sonu Subudhi

  • TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism.

    Nature communications

    Authors: Astrid F Feiten, Kilian Dahm, Kai Schlepckow, Bettina van Lengerich, Jung H Suh, Anika Reifschneider, Benedikt Wefers, Laura M Bartos, Karin Wind-Mark, Lis de Weerd, Thomas Ulas, Elena De-Domenico, Pia Grundschöttel, Stefan Paulusch, Benjamin Tast, Tamisa Honda, Stephan A Müller, Matthias Becker, Igor Khalin, Alessio Ricci, Arthur Liesz, Bettina Brunner, Claudia Krenner, Katrin Buschmann, Brigitte Nuscher, Lena Spieth, Niklas Junker, Stefan A Berghoff, Sonnet S Davis, Jonas J Neher, Wolfgang Wurst, Nikolaus Plesnila, Joseph W Lewcock, Mikael Simons, Stefan F Lichtenthaler, Gilbert Di Paolo, Matthias Brendel, Anja Capell, Kathryn M Monroe, Joachim L Schultze, Christian Haass

  • Genetic contribution to severe COVID-19 in adults under 60 years without major comorbidities in the German National Pandemic Cohort Network (NAPKON).

    Human genomics

    Authors: Ayda Abolhassani, T Madhusankha Alawathurage, Axel Schmidt, Fabian Brand, Laura L Kilarski, Heidi Altmann, Edgar Dahl, Sandra Frank, Siri Göpel, Frank Hanses, Johannes Christian Hellmuth, Christian Herr, Achim J Kaasch, Robin Kobbe, Margarethe Justine Konik, Isabell Pink, Christoph Römmele, Jan Rupp, Christian S Scheer, Marc A Schneider, Christoph Stellbrink, Hans Christian Stubbe, Phil-Robin Tepasse, Andreas Teufel, István Vadász, Maria J G T Vehreschild, Martin Witzenrath, Gabriele Anton, Isabel Bröhl, Susanne Herold, Thomas Illig, Steffi Jiru-Hillmann, Peter Krawitz, Lazar Mitrov, Alexandra Philipsen, Sina M Pütz, Markus M Noethen, Peter Nuernberg, Jens-Peter Reese, Olaf Riess, Stefan Schreiber, Joachim Schultze, Fridolin Steinbeis, J Janne Vehreschild, Christian Wildberg, Kerstin U Ludwig, Eva C Schulte

  • Analysis of drug-drug interactions between psychiatric drugs in spontaneous adverse drug reaction reports from EudraVigilance.

    Naunyn-Schmiedeberg's archives of pharmacology

    Authors: Diana Dubrall, Patrick Christ, Miriam Böhme, Martina Hahn, Matthias Schmid, Catharina Scholl

  • Effect of therapeutic plasma exchange on acquired hypocholesterolemia in patients with septic shock: a post hoc analysis of the two exchange trials.

    Critical care (London, England)

    Authors: Thorben Pape, Daniel A Hofmaenner, Dorothea M Heuberger, Ralf Lichtinghagen, Korbinian Brand, Heiko Schenk, Christian Putensen, Benjamin Seeliger, Christian Bode, Klaus Stahl, Sascha David

  • Longitudinal plasma proteomic signatures of elite and viremic spontaneous HIV controllers.

    Nature communications

    Authors: Nadira Vadaq, Albert L Groenendijk, Jéssica C Dos Santos, Kavita Mehta, Ferdinand W N M Wit, Wilhelm A J W Vos, Martinus J T Blaauw, Louise E van Eekeren, Laurens Lambrechts, Sofie Rutsaert, Erni J Nelwan, Cheng-Jian Xu, Leo A B Joosten, Quirijn de Mast, Vasiliki Matzaraki, Jan van Lunzen, Casper Rokx, Annelies Verbon, Mihai G Netea, Linos Vandekerckhove, André J A M van der Ven

  • Western lifestyle linked to maladaptive trained immunity.

    eLife

    Authors: Aurelia Josephine Merbecks, Christabel Mennicken, Dennis Marinus de Graaf, Kateryna Shkarina, Theresa Wagner, Eicke Latz

  • Spatiotemporal dynamics of ecto-5'-nucleotidase (CD73) in mouse retina under physiological conditions.

    Development (Cambridge, England)

    Authors: Ryutaro Ishii, Keisuke Sakurai, Nao Hosomi, Bernd K Fleischmann, Seiya Mizuno, Kenichi Kimura, Hiromi Yanagisawa

  • Therapy-refractory lymphatic fistulas following complete lymph node dissection in malignant melanoma: local radiotherapy as an effective therapeutic modality to avoid cancer treatment delay.

    Langenbeck's archives of surgery

    Authors: Johannes Röttgen, Maximilian Coerper, Jonas Dohmen, Daniel Weissinger, Steffi Marx, Philipp Leyendecker, Judith Sirokay, Azin Jafari, Jennifer Landsberg, Jörg C Kalff, Philipp Lingohr, Alexander Semaan

  • [Precision immunotherapy improves organ dysfunction in sepsis].

    Die Anaesthesiologie

    Authors: Lennart Wild, Christian Bode