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  • Top publication

    Immune tolerance against infused FVIII in hemophilia A is mediated by PD-L1+ Tregs.

    The Journal of clinical investigation

    Authors: Janine Becker-Gotot, Mirjam Meissner, Vadim Kotov, Blanca Jurado-Mestre, Andrea Maione, Andreas Pannek, Thilo Albert, Chrystel Flores, Frank A Schildberg, Paul A Gleeson, Birgit M Reipert, Johannes Oldenburg, Christian Kurts

  • The PI3K inhibitor pictilisib and the multikinase inhibitors pazopanib and sorafenib have an impact on Rac1 level and migration of medulloblastoma in vitro.

    Journal of cellular and molecular medicine

    Authors: Leonie F Schoen, Rogerio B Craveiro, Torsten Pietsch, Thomas Moritz, Anja Troeger, Silvia Jordans, Dagmar Dilloo

  • A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.

    Journal of immunology (Baltimore, Md. : 1950)

    Authors: Loránd Göczi, Mária Csumita, Attila Horváth, Gergely Nagy, Szilárd Póliska, Matteo Pigni, Christoph Thelemann, Bence Dániel, Hamidreza Mianesaz, Tamás Varga, Kaushik Sen, Sunil K Raghav, John W Schoggins, Laszlo Nagy, Hans Acha-Orbea, Felix Meissner, Walter Reith, Lajos Széles

  • Toward personalized immunotherapy in sepsis: The PROVIDE randomized clinical trial.

    Cell reports. Medicine

    Authors: Konstantinos Leventogiannis, Evdoxia Kyriazopoulou, Nikolaos Antonakos, Antigone Kotsaki, Iraklis Tsangaris, Dimitra Markopoulou, Inge Grondman, Nikoleta Rovina, Vassiliki Theodorou, Eleni Antoniadou, Ioannis Koutsodimitropoulos, George Dalekos, Glykeria Vlachogianni, Karolina Akinosoglou, Vassileios Koulouras, Apostolos Komnos, Theano Kontopoulou, Athanassios Prekates, Antonia Koutsoukou, Jos W M van der Meer, George Dimopoulos, Miltiades Kyprianou, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Nestin expression in osteocytes following myeloablation and during bone marrow metastasis.

    British journal of haematology

    Authors: Ruth-Miriam Koerber, Rebekka K Schneider, Jessica Ellen Pritchard, Lino L Teichmann, Udo Schumacher, Peter Brossart, Ines Gütgemann

  • Adverse Drug Reactions in Children: Comparison of Reports Collected in a Pharmacovigilance Project Versus Spontaneously Collected ADR Reports.

    Paediatric drugs

    Authors: Sarah Leitzen, Diana Dubrall, Irmgard Toni, Julia Stingl, Patrick Christ, Ursula Köberle, Matthias Schmid, Antje Neubert, Bernhardt Sachs

  • Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.

    Nature communications

    Authors: Kan Xie, Helmut Fuchs, Enzo Scifo, Dan Liu, Ahmad Aziz, Juan Antonio Aguilar-Pimentel, Oana Veronica Amarie, Lore Becker, Patricia da Silva-Buttkus, Julia Calzada-Wack, Yi-Li Cho, Yushuang Deng, A Cole Edwards, Lillian Garrett, Christina Georgopoulou, Raffaele Gerlini, Sabine M Hölter, Tanja Klein-Rodewald, Michael Kramer, Stefanie Leuchtenberger, Dimitra Lountzi, Phillip Mayer-Kuckuk, Lena L Nover, Manuela A Oestereicher, Clemens Overkott, Brandon L Pearson, Birgit Rathkolb, Jan Rozman, Jenny Russ, Kristina Schaaf, Nadine Spielmann, Adrián Sanz-Moreno, Claudia Stoeger, Irina Treise, Daniele Bano, Dirk H Busch, Jochen Graw, Martin Klingenspor, Thomas Klopstock, Beverly A Mock, Paolo Salomoni, Carsten Schmidt-Weber, Marco Weiergräber, Eckhard Wolf, Wolfgang Wurst, Valérie Gailus-Durner, Monique M B Breteler, Martin Hrabě de Angelis, Dan Ehninger

  • Ex Vivo Modeling of the PC (Protein C) Pathway Using Endothelial Cells and Plasma: A Personalized Approach.

    Arteriosclerosis, thrombosis, and vascular biology

    Authors: Nadine Schwarz, Jens Müller, Hamideh Yadegari, Hannah L McRae, Sara Reda, Nasim Shahidi Hamedani, Johannes Oldenburg, Bernd Pötzsch, Heiko Rühl

  • Characterization of B cells in lupus erythematosus skin biopsies in the context of different immune cell infiltration patterns.

    Frontiers in medicine

    Authors: Luka de Vos, Tugce Guel, Dennis Niebel, Sandra Bald, Adrian Ter Steege, Thomas Bieber, Joerg Wenzel

  • Spatial Immunephenotypes of Distant Metastases but not Matched Primary Urothelial Carcinomas Predict Response to Immune Checkpoint Inhibition.

    European urology

    Authors: Franziska Erlmeier, Niklas Klümper, Laura Landgraf, Pamela L Strissel, Reiner Strick, Danijel Sikic, Helge Taubert, Sven Wach, Carol I Geppert, Veronika Bahlinger, Johannes Breyer, Manuel Ritter, Christian Bolenz, Florian Roghmann, Philipp Erben, Kristina Schwamborn, Ralph M Wirtz, Thomas Horn, Bernd Wullich, Michael Hölzel, Arndt Hartmann, Jürgen E Gschwend, Wilko Weichert, Markus Eckstein