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Publications

featured publications

  • Trained immunity-related vaccines: innate immune memory and heterologous protection against infections.

    Trends in molecular medicine

    Authors: Athanasios Ziogas, Mihai G Netea

  • Clonal Hematopoiesis Is Associated With Low CD4 Nadir and Increased Residual HIV Transcriptional Activity in Virally Suppressed Individuals With HIV.

    The Journal of infectious diseases

    Authors: Wouter A van der Heijden, Rosanne C van Deuren, Lisa van de Wijer, Inge C L van den Munckhof, Marloes Steehouwer, Niels P Riksen, Mihai G Netea, Quirijn de Mast, Linos Vandekerckhove, Richarda M de Voer, Andre J van der Ven, Alexander Hoischen

  • Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19.

    Frontiers in immunology

    Authors: Zhaoli Liu, Gizem Kilic, Wenchao Li, Ozlem Bulut, Manoj Kumar Gupta, Bowen Zhang, Cancan Qi, He Peng, Hsin-Chieh Tsay, Chai Fen Soon, Yonatan Ayalew Mekonnen, Anaísa Valido Ferreira, Caspar I van der Made, Bram van Cranenbroek, Hans J P M Koenen, Elles Simonetti, Dimitri Diavatopoulos, Marien I de Jonge, Lisa Müller, Heiner Schaal, Philipp N Ostermann, Markus Cornberg, Britta Eiz-Vesper, Frank van de Veerdonk, Reinout van Crevel, Leo A B Joosten, Jorge Domínguez-Andrés, Cheng-Jian Xu, Mihai G Netea, Yang Li

  • Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes.

    The Journal of clinical investigation

    Authors: Bowen Zhang, Simone Jcfm Moorlag, Jorge Dominguez-Andres, Özlem Bulut, Gizem Kilic, Zhaoli Liu, Reinout van Crevel, Cheng-Jian Xu, Leo Ab Joosten, Mihai G Netea, Yang Li

  • Evolutionary Trajectories of Complex Traits in European Populations of Modern Humans.

    Frontiers in genetics

    Authors: Yunus Kuijpers, Jorge Domínguez-Andrés, Olivier B Bakker, Manoj Kumar Gupta, Martin Grasshoff, Cheng-Jian Xu, Leo A B Joosten, Jaume Bertranpetit, Mihai G Netea, Yang Li

  • The gut microbiome as mediator between diet and its impact on immune function.

    Scientific reports

    Authors: Huiqing Shi, Rob Ter Horst, Suzanne Nielen, Mirjam Bloemendaal, Martin Jaeger, Irma Joosten, Hans Koenen, Leo A B Joosten, Lizanne J S Schweren, Alejandro Arias Vasquez, Mihai G Netea, Jan Buitelaar

  • Borrelia burgdorferi inhibits NADPH-mediated reactive oxygen species production through the mTOR pathway.

    Ticks and tick-borne diseases

    Authors: Mariska Kerstholt, Michelle Brouwer, Marcel Te Vrugt, Marije Oosting, Mihai G Netea, Leo A B Joosten

  • Development and validation of SCOPE score: A clinical score to predict COVID-19 pneumonia progression to severe respiratory failure.

    Cell reports. Medicine

    Authors: Evangelos J Giamarellos-Bourboulis, Garyfallia Poulakou, Aline de Nooijer, Haralampos Milionis, Simeon Metallidis, Michalis Ploumidis, Pinelopi Grigoropoulou, Aggeliki Rapti, Francesco Vladimiro Segala, Evangelos Balis, Efthymia Giannitsioti, Paola Rodari, Ilias Kainis, Zoi Alexiou, Emanuele Focà, Brollo Lucio, Nikoletta Rovina, Laura Scorzolini, Maria Dafni, Sofia Ioannou, Alessandro Tomelleri, Katerina Dimakou, Glykeria Tzatzagou, Maria Chini, Matteo Bassetti, Christina Trakatelli, George Tsoukalas, Carlo Selmi, Charilaos Samaras, Maria Saridaki, Athina Pyrpasopoulou, Elisabeth Kaldara, Ilias Papanikolaou, Aikaterini Argyraki, Karolina Akinosoglou, Marina Koupetori, Periklis Panagopoulos, George N Dalekos, Mihai G Netea

  • BCG vaccination provides protection against IAV but not SARS-CoV-2.

    Cell reports

    Authors: Eva Kaufmann, Nargis Khan, Kim A Tran, Antigona Ulndreaj, Erwan Pernet, Ghislaine Fontes, Andréanne Lupien, Patrice Desmeules, Fiona McIntosh, Amina Abow, Simone J C F M Moorlag, Priya Debisarun, Karen Mossman, Arinjay Banerjee, Danielle Karo-Atar, Mina Sadeghi, Samira Mubareka, Donald C Vinh, Irah L King, Clinton S Robbins, Marcel A Behr, Mihai G Netea, Philippe Joubert, Maziar Divangahi

  • BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial.

    NPJ vaccines

    Authors: Joshua Gillard, Bastiaan A Blok, Daniel R Garza, Prashanna Balaji Venkatasubramanian, Elles Simonetti, Marc J Eleveld, Guy A M Berbers, Pieter G M van Gageldonk, Irma Joosten, Ronald de Groot, L Charlotte J de Bree, Reinout van Crevel, Marien I de Jonge, Martijn A Huynen, Mihai G Netea, Dimitri A Diavatopoulos