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  • Unveiling IRF4-steered regulation of context-dependent effector programs in CD4 T cells under Th17- and Treg-skewing conditions.

    Cell reports

    Authors: Anna Gabele, Maximilian Sprang, Mert Cihan, Mareen Welzel, Assel Nurbekova, Karolina Romaniuk, Sarah Dietzen, Matthias Klein, Georg Bündgen, Maxim Emelianov, Gregory Harms, Krishnaraj Rajalingam, Tanja Ziesmann, Katrin Pape, Beatrice Wasser, David Gomez-Zepeda, Kathrin Braband, Michael Delacher, Niels Lemmermann, Stefan Bittner, Miguel A Andrade-Navarro, Stefan Tenzer, Katja Luck, Tobias Bopp, Ute Distler

  • A functional single-cell metabolic survey identifies Elovl1 as a target to enhance CD8 T cell fitness in solid tumours.

    Nature metabolism

    Authors: Samantha Pretto, Qian Yu, Pierre Bourdely, Sarah Trusso Cafarello, Heleen H Van Acker, Joren Verelst, Elena Richiardone, Lotte Vanheer, Amir Roshanzadeh, Franziska Schneppenheim, Charlotte Cresens, Maria Livia Sassano, Jonas Dehairs, Martin Carion, Shehab Ismail, Patrizia Agostinis, Susana Rocha, Tobias Bald, Johan Swinnen, Cyril Corbet, Sophia Y Lunt, Bernard Thienpont, Mario Di Matteo, Massimiliano Mazzone

  • Ablation of symptomatic uterine fibroids with the Mirabilis system for rapid noninvasive ultrasound-guided high-intensity focused ultrasound (HIFU): a prospective observational clinical study.

    La Radiologia medica

    Authors: Tolga Tonguc, Oleksandr Savchenko, Olga Ramig, Judith M Stader, Franziska Kießling, Jim Küppers, Eva K Egger, Marcus Thudium, Patrick Martin, Wayne Poll, Hans H Schild, Rupert Conrad, Markus Essler, Alexander Mustea, Holger M Strunk, Milka Marinova

  • DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform.

    Bioinformatics advances

    Authors: Demetris Avraam, Rebecca C Wilson, Noemi Aguirre Chan, Soumya Banerjee, Tom R P Bishop, Olly Butters, Tim Cadman, Luise Cederkvist, Liesbeth Duijts, Xavier Escribà Montagut, Hugh Garner, Gonçalo Gonçalves, Juan R González, Sido Haakma, Mette Hartlev, Jan Hasenauer, Manuel Huth, Eleanor Hyde, Vincent W V Jaddoe, Yannick Marcon, Michaela Th Mayrhofer, Fruzsina Molnar-Gabor, Andrei Scott Morgan, Madeleine Murtagh, Marc Nestor, Anne-Marie Nybo Andersen, Simon Parker, Angela Pinot de Moira, Florian Schwarz, Katrine Strandberg-Larsen, Morris A Swertz, Marieke Welten, Stuart Wheater, Paul Burton

  • Right heart failure and mortality in patients undergoing transcatheter tricuspid valve interventions.

    International journal of cardiology

    Authors: Edoardo Pancaldi, Marianna Adamo, Matteo Pagnesi, Giulio Russo, Hannes Alessandrini, Martin Andreas, Daniel Braun, Dario Cani, Kim A Connelly, Paolo Denti, Rodrigo Estevez-Loureiro, Neil Fam, Rebecca T Hahn, Claudia Harr, Joerg Hausleiter, Dominique Himbert, Daniel Kalbacher, Edwin Ho, Azeem Latib, Edith Lubos, Sebastian Ludwig, Philipp Lurz, Vanessa Monivas, Georg Nickenig, Daniela Pedicino, Giovanni Pedrazzini, Fabien Praz, Joseph Rodes-Cabau, Christian Besler, Anne Rebecca Schöber, Joachim Schofer, Andrea Scotti, Kerstin Piayda, Horst Sievert, Gilbert H L Tang, David Messika-Zeitoun, Holger Thiele, Florian Schlotter, Ralph Stephan von Bardeleben, John Webb, Julien Dreyfus, Stephan Windecker, Martin Leon, Francesco Maisano, Marco Metra, Maurizio Taramasso

  • An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis.

    Nature communications

    Authors: Omar El Bounkari, Chunfang Zan, Bishan Yang, Simon Ebert, Jonas Wagner, Elina Bugar, Naomi Kramer, Priscila Bourilhon, Christos Kontos, Marlies Zarwel, Dzmitry Sinitski, Jelena Milic, Yvonne Jansen, Wolfgang E Kempf, Nadja Sachs, Lars Maegdefessel, Hao Ji, Ozgun Gokce, Fabien Riols, Mark Haid, Simona Gerra, Adrian Hoffmann, Markus Brandhofer, Maida Avdic, Richard Bucala, Remco T A Megens, Nienke Willemsen, Denise Messerer, Christian Schulz, Alexander Bartelt, Tobias Harm, Dominik Rath, Yvonne Döring, Meinrad Gawaz, Christian Weber, Aphrodite Kapurniotu, Jürgen Bernhagen

  • Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth.

    Nature communications

    Authors: Greta Ehlers, Annika Marie Tödtmann, Lisa Holsten, Maike Willers, Julia Heckmann, Jennifer Schöning, Maximilian Richter, Anna Sophie Heinemann, Sabine Pirr, Alexander Heinz, Christian Dopfer, Kristian Händler, Matthias Becker, Johanna Büchel, Achim Wöckel, Constantin von Kaisenberg, Gesine Hansen, Karsten Hiller, Joachim L Schultze, Christoph Härtel, Wolfgang Kastenmüller, Martin Vaeth, Thomas Ulas, Dorothee Viemann

  • Come together, right now! ZCCHC3 orchestrates cytosolic nucleic acid sensing through phase condensation.

    Molecular cell

    Authors: Rebecca Barker, Eva Bartok

  • Single-cell immune aging clocks reveal inter-individual heterogeneity during infection and vaccination.

    Nature aging

    Authors: Wenchao Li, Zhenhua Zhang, Saumya Kumar, Javier Botey-Bataller, Martijn Zoodsma, Ali Ehsani, Qiuyao Zhan, Ahmed Alaswad, Liang Zhou, Inge Grondman, Valerie Koeken, Jian Yang, Gang Wang, Sonja Volland, Tania O Crişan, Leo A B Joosten, Thomas Illig, Cheng-Jian Xu, Mihai G Netea, Yang Li

  • Targeting mTOR in myeloid cells prevents infection-associated inflammation.

    iScience

    Authors: Yohana C Toner, Jazz Munitz, Geoffrey Prevot, Judit Morla-Folch, William Wang, Yuri van Elsas, Bram Priem, Jeroen Deckers, Tom Anbergen, Thijs J Beldman, Eliane E S Brechbühl, Muhammed D Aksu, Athanasios Ziogas, Sebastian A Sarlea, Mumin Ozturk, Zhenhua Zhang, Wenchao Li, Yang Li, Alexander Maier, Jessica C Fernandes, Glenn A O Cremers, Bas van Genabeek, Joost H C M Kreijtz, Esther Lutgens, Niels P Riksen, Henk M Janssen, Serge H M Söntjens, Freek J M Hoeben, Ewelina Kluza, Gagandeep Singh, Evangelos J Giamarellos-Bourboulis, Michael Schotsaert, Raphaël Duivenvoorden, Roy van der Meel, Leo A B Joosten, Lei Cai, Ryan E Temel, Zahi A Fayad, Musa M Mhlanga, Mandy M T van Leent, Abraham J P Teunissen, Mihai G Netea, Willem J M Mulder