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  • The effector program of human CD8 T cells supports tissue remodeling.

    The Journal of experimental medicine

    Authors: Michael Delacher, Lisa Schmidleithner, Malte Simon, Philipp Stüve, Lieke Sanderink, Agnes Hotz-Wagenblatt, Marina Wuttke, Kathrin Schambeck, Brigitte Ruhland, Veronika Hofmann, Sebastian Bittner, Uwe Ritter, Asmita Pant, Sara Salome Helbich, Morten Voss, Niels A Lemmermann, Lisa Bessiri-Schake, Toszka Bohn, Andreas Eigenberger, Ayse Nur Menevse, Claudia Gebhard, Nicholas Strieder, Hinrich Abken, Michael Rehli, Jochen Huehn, Philipp Beckhove, Thomas Hehlgans, Henrik Junger, Edward K Geissler, Lukas Prantl, Jens M Werner, Christian Schmidl, Benedikt Brors, Charles D Imbusch, Markus Feuerer

  • Direct antigen presentation is the canonical pathway of cytomegalovirus CD8 T-cell priming regulated by balanced immune evasion ensuring a strong antiviral response.

    Frontiers in immunology

    Authors: Julia K Büttner, Sara Becker, Annette Fink, Melanie M Brinkmann, Rafaela Holtappels, Matthias J Reddehase, Niels A Lemmermann

  • Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effector-memory cells.

    PLoS pathogens

    Authors: Rafaela Holtappels, Sara Becker, Sara Hamdan, Kirsten Freitag, Jürgen Podlech, Niels A Lemmermann, Matthias J Reddehase