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featured publications

  • Prosaposin mediates inflammation in atherosclerosis.

    Science translational medicine

    Authors: Mandy M T van Leent, Thijs J Beldman, Yohana C Toner, Marnix A Lameijer, Nils Rother, Siroon Bekkering, Abraham J P Teunissen, Xianxiao Zhou, Roy van der Meel, Joost Malkus, Sheqouia A Nauta, Emma D Klein, Francois Fay, Brenda L Sanchez-Gaytan, Carlos Pérez-Medina, Ewelina Kluza, Yu-Xiang Ye, Gregory Wojtkiewicz, Edward A Fisher, Filip K Swirski, Matthias Nahrendorf, Bin Zhang, Yang Li, Bowen Zhang, Leo A B Joosten, Gerard Pasterkamp, Arjan Boltjes, Zahi A Fayad, Esther Lutgens, Mihai G Netea, Niels P Riksen, Willem J M Mulder, Raphaël Duivenvoorden

  • Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis.

    Cell reports

    Authors: Kshiti Phulphagar, Lars I Kühn, Stefan Ebner, Annika Frauenstein, Jonathan J Swietlik, Jan Rieckmann, Felix Meissner

  • NKG2D and its ligands as cytotoxic factors in cutaneous lupus erythematosus.

    Experimental dermatology

    Authors: Gero Vorwerk, Sabine Zahn, Thomas Bieber, Joerg Wenzel

  • Helios-expressing CD8 T cells are decreased in patients with systemic lupus erythematosus.

    Lupus

    Authors: Tobias Aw Holderried, Mareike Kruse, Michael Serries, Peter Brossart, Dominik Wolf, Anna Maria Wolf

  • CiliaQ: a simple, open-source software for automated quantification of ciliary morphology and fluorescence in 2D, 3D, and 4D images.

    The European physical journal. E, Soft matter

    Authors: Jan Niklas Hansen, Sebastian Rassmann, Birthe Stüven, Nathalie Jurisch-Yaksi, Dagmar Wachten

  • An open label trial of anakinra to prevent respiratory failure in COVID-19.

    eLife

    Authors: Evdoxia Kyriazopoulou, Periklis Panagopoulos, Symeon Metallidis, George N Dalekos, Garyphallia Poulakou, Nikolaos Gatselis, Eleni Karakike, Maria Saridaki, Georgia Loli, Aggelos Stefos, Danai Prasianaki, Sarah Georgiadou, Olga Tsachouridou, Vasileios Petrakis, Konstantinos Tsiakos, Maria Kosmidou, Vassiliki Lygoura, Maria Dareioti, Haralampos Milionis, Ilias C Papanikolaou, Karolina Akinosoglou, Dimitra-Melia Myrodia, Areti Gravvani, Aliki Stamou, Theologia Gkavogianni, Konstantina Katrini, Theodoros Marantos, Ioannis P Trontzas, Konstantinos Syrigos, Loukas Chatzis, Stamatios Chatzis, Nikolaos Vechlidis, Christina Avgoustou, Stamatios Chalvatzis, Miltiades Kyprianou, Jos Wm van der Meer, Jesper Eugen-Olsen, Mihai G Netea, Evangelos J Giamarellos-Bourboulis

  • Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background.

    Scientific reports

    Authors: Lech Kaczmarczyk, Nicole Reichenbach, Nelli Blank, Maria Jonson, Lars Dittrich, Gabor C Petzold, Walker S Jackson

  • Circulating chaperones in patients with aortic valve stenosis undergoing TAVR: impact of concomitant chronic kidney disease.

    Translational research : the journal of laboratory and clinical medicine

    Authors: Adem Aksoy, Baravan Al-Kassou, Muntadher Al Zaidi, Jasmin Shamekhi, Elena Repges, Alexander Sedaghat, Marc Ulrich Becher, Hendrik Treede, Felix Jansen, Jan-Malte Sinning, Sebastian Zimmer, Georg Nickenig, Vedat Tiyerili

  • Hippocampal hyperactivity in a rat model of Alzheimer's disease.

    Journal of neurochemistry

    Authors: Liudmila Sosulina, Manuel Mittag, Hans-Rüdiger Geis, Kerstin Hoffmann, Igor Klyubin, Yingjie Qi, Julia Steffen, Detlef Friedrichs, Niklas Henneberg, Falko Fuhrmann, Daniel Justus, Kevin Keppler, A Claudio Cuello, Michael J Rowan, Martin Fuhrmann, Stefan Remy

  • A modular approach toward producing nanotherapeutics targeting the innate immune system.

    Science advances

    Authors: Mandy M T van Leent, Anu E Meerwaldt, Alexandre Berchouchi, Yohana C Toner, Marianne E Burnett, Emma D Klein, Anna Vera D Verschuur, Sheqouia A Nauta, Jazz Munitz, Geoffrey Prévot, Esther M van Leeuwen, Farideh Ordikhani, Vera P Mourits, Claudia Calcagno, Philip M Robson, George Soultanidis, Thomas Reiner, Rick R M Joosten, Heiner Friedrich, Joren C Madsen, Ewelina Kluza, Roy van der Meel, Leo A B Joosten, Mihai G Netea, Jordi Ochando, Zahi A Fayad, Carlos Pérez-Medina, Willem J M Mulder, Abraham J P Teunissen