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Featured publications

  • The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux.

    Scientific reports

    Authors: Federica Cavaliere, Alessandra Fornarelli, Fabio Bertan, Rossella Russo, Anaïs Marsal-Cots, Luigi Antonio Morrone, Annagrazia Adornetto, Maria Tiziana Corasaniti, Daniele Bano, Giacinto Bagetta, Pierluigi Nicotera

  • Direct targeting of Gα and Gα oncoproteins in cancer cells.

    Science signaling

    Authors: Suvi Annala, Xiaodong Feng, Naveen Shridhar, Funda Eryilmaz, Julian Patt, JuHee Yang, Eva M Pfeil, Rodolfo Daniel Cervantes-Villagrana, Asuka Inoue, Felix Häberlein, Tanja Slodczyk, Raphael Reher, Stefan Kehraus, Stefania Monteleone, Ramona Schrage, Nina Heycke, Ulrike Rick, Sandra Engel, Alexander Pfeifer, Peter Kolb, Gabriele König, Moritz Bünemann, Thomas Tüting, José Vázquez-Prado, J Silvio Gutkind, Evelyn Gaffal, Evi Kostenis

  • Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

    Nature cell biology

    Authors: Camilla Salvagno, Metamia Ciampricotti, Sander Tuit, Cheei-Sing Hau, Antoinette van Weverwijk, Seth B Coffelt, Kelly Kersten, Kim Vrijland, Kevin Kos, Thomas Ulas, Ji-Ying Song, Chia-Huey Ooi, Dominik Rüttinger, Philippe A Cassier, Jos Jonkers, Joachim L Schultze, Carola H Ries, Karin E de Visser

  • Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

    Kidney international

    Authors: Victor G Puelles, David Fleck, Lena Ortz, Stella Papadouri, Thiago Strieder, Alexander M C Böhner, James W van der Wolde, Michael Vogt, Turgay Saritas, Christoph Kuppe, Astrid Fuss, Sylvia Menzel, Barbara M Klinkhammer, Gerhard Müller-Newen, Felix Heymann, Leon Decker, Fabian Braun, Oliver Kretz, Tobias B Huber, Etsuo A Susaki, Hiroki R Ueda, Peter Boor, Jürgen Floege, Rafael Kramann, Christian Kurts, John F Bertram, Marc Spehr, David J Nikolic-Paterson, Marcus J Moeller

  • LipidII interaction with specific residues of Mycobacterium tuberculosis PknB extracytoplasmic domain governs its optimal activation.

    Nature communications

    Authors: Prabhjot Kaur, Marvin Rausch, Basanti Malakar, Uchenna Watson, Nikhil P Damle, Yogesh Chawla, Sandhya Srinivasan, Kanika Sharma, Tanja Schneider, Gagan Deep Jhingan, Deepak Saini, Debasisa Mohanty, Fabian Grein, Vinay Kumar Nandicoori

  • Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches.

    Science (New York, N.Y.)

    Authors: Svetoslav Chakarov, Hwee Ying Lim, Leonard Tan, Sheau Yng Lim, Peter See, Josephine Lum, Xiao-Meng Zhang, Shihui Foo, Satoshi Nakamizo, Kaibo Duan, Wan Ting Kong, Rebecca Gentek, Akhila Balachander, Daniel Carbajo, Camille Bleriot, Benoit Malleret, John Kit Chung Tam, Sonia Baig, Muhammad Shabeer, Sue-Anne Ee Shiow Toh, Andreas Schlitzer, Anis Larbi, Thomas Marichal, Bernard Malissen, Jinmiao Chen, Michael Poidinger, Kenji Kabashima, Marc Bajenoff, Lai Guan Ng, Veronique Angeli, Florent Ginhoux

  • Preliminary results of biodistribution and dosimetric analysis of [Ga]Ga-DOTA: a new zoledronate-based bisphosphonate for PET/CT diagnosis of bone diseases.

    Annals of nuclear medicine

    Authors: Ambreen Khawar, Elisabeth Eppard, Frank Roesch, Hojjat Ahmadzadehfar, Stefan Kürpig, Michael Meisenheimer, Florian C Gaertner, Markus Essler, Ralph A Bundschuh

  • Diagnosis of peri-prosthetic loosening of total hip and knee arthroplasty using F-Fluoride PET/CT.

    Oncotarget

    Authors: Sebastian Koob, Florian C Gaertner, Tom Rainer Jansen, Jan Schmolders, Sascha Gravius, Holger Strunk, Dieter Christian Wirtz, Markus Essler

  • Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice.

    Scientific reports

    Authors: Kathrin Thiem, Geerte Hoeke, Susan van den Berg, Anneke Hijmans, Cor W M Jacobs, Enchen Zhou, Isabel M Mol, Maria Mouktaroudi, Johan Bussink, Thirumala D Kanneganti, Esther Lutgens, Rinke Stienstra, Cees J Tack, Mihai G Netea, Patrick C N Rensen, Jimmy F P Berbée, Janna A van Diepen

  • Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes.

    Nature communications

    Authors: Marlijn van der Poel, Thomas Ulas, Mark R Mizee, Cheng-Chih Hsiao, Suzanne S M Miedema, Adelia, Karianne G Schuurman, Boy Helder, Sander W Tas, Joachim L Schultze, Jörg Hamann, Inge Huitinga