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featured publications

  • Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.

    PLoS pathogens

    Authors: Matteo Bosso, Caterina Prelli Bozzo, Dominik Hotter, Meta Volcic, Christina M Stürzel, Annika Rammelt, Yi Ni, Stephan Urban, Miriam Becker, Mario Schelhaas, Sabine Wittmann, Maria H Christensen, Florian I Schmidt, Thomas Gramberg, Konstantin M J Sparrer, Daniel Sauter, Frank Kirchhoff

  • Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

    Cell

    Authors: Jonas Schulte-Schrepping, Nico Reusch, Daniela Paclik, Kevin Baßler, Stephan Schlickeiser, Bowen Zhang, Benjamin Krämer, Tobias Krammer, Sophia Brumhard, Lorenzo Bonaguro, Elena De Domenico, Daniel Wendisch, Martin Grasshoff, Theodore S Kapellos, Michael Beckstette, Tal Pecht, Adem Saglam, Oliver Dietrich, Henrik E Mei, Axel R Schulz, Claudia Conrad, Désirée Kunkel, Ehsan Vafadarnejad, Cheng-Jian Xu, Arik Horne, Miriam Herbert, Anna Drews, Charlotte Thibeault, Moritz Pfeiffer, Stefan Hippenstiel, Andreas Hocke, Holger Müller-Redetzky, Katrin-Moira Heim, Felix Machleidt, Alexander Uhrig, Laure Bosquillon de Jarcy, Linda Jürgens, Miriam Stegemann, Christoph R Glösenkamp, Hans-Dieter Volk, Christine Goffinet, Markus Landthaler, Emanuel Wyler, Philipp Georg, Maria Schneider, Chantip Dang-Heine, Nick Neuwinger, Kai Kappert, Rudolf Tauber, Victor Corman, Jan Raabe, Kim Melanie Kaiser, Michael To Vinh, Gereon Rieke, Christian Meisel, Thomas Ulas, Matthias Becker, Robert Geffers, Martin Witzenrath, Christian Drosten, Norbert Suttorp, Christof von Kalle, Florian Kurth, Kristian Händler, Joachim L Schultze, Anna C Aschenbrenner, Yang Li, Jacob Nattermann, Birgit Sawitzki, Antoine-Emmanuel Saliba, Leif Erik Sander

  • Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study.

    Cell reports. Medicine

    Authors: Simone J C F M Moorlag, Rosanne C van Deuren, Cornelis H van Werkhoven, Martin Jaeger, Priya Debisarun, Esther Taks, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Thijs Ten Doesschate, Maartje C Cleophas, Sanne Smeekens, Marije Oosting, Frank L van de Veerdonk, Leo A B Joosten, Jaap Ten Oever, Jos W M van der Meer, Nigel Curtis, Peter Aaby, Christine Stabell-Benn, Evangelos J Giamarellos-Bourboulis, Marc Bonten, Reinout van Crevel, Mihai G Netea

  • Mgs1 protein supports genome stability via recognition of G-quadruplex DNA structures.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Authors: Theresa Zacheja, Agnes Toth, Gabor M Harami, Qianlu Yang, Eike Schwindt, Mihály Kovács, Katrin Paeschke, Peter Burkovics

  • Cartilage Regeneration with Cell-free Type 1 Collagen Matrix - Past, Present and Future (Part 1 - Clinical Aspects).

    Zeitschrift fur Orthopadie und Unfallchirurgie

    Authors: Philip Peter Roessler, Turgay Efe, Dieter Christian Wirtz, Frank Alexander Schildberg

  • The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance.

    International journal of cancer

    Authors: Aysel Ahadova, Toni T Seppälä, Christoph Engel, Richard Gallon, John Burn, Elke Holinski-Feder, Verena Steinke-Lange, Gabriela Möslein, Maartje Nielsen, Sanne W Ten Broeke, Luigi Laghi, Mev Dominguez-Valentin, Gabriel Capella, Finlay Macrae, Rodney Scott, Robert Hüneburg, Jacob Nattermann, Michael Hoffmeister, Hermann Brenner, Hendrik Bläker, Magnus von Knebel Doeberitz, Julian R Sampson, Hans Vasen, Jukka-Pekka Mecklin, Pål Møller, Matthias Kloor

  • Rational discovery of molecular glue degraders via scalable chemical profiling.

    Nature chemical biology

    Authors: Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C Müller, Johannes Zuber, Matthias Geyer, Nicolas H Thomä, Stefan Kubicek, Georg E Winter

  • Top publication

    Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma.

    Immunity

    Authors: Maike Effern, Nicole Glodde, Matthias Braun, Jana Liebing, Helena N Boll, Michelle Yong, Emma Bawden, Daniel Hinze, Debby van den Boorn-Konijnenberg, Mila Daoud, Pia Aymans, Jennifer Landsberg, Mark J Smyth, Lukas Flatz, Thomas Tüting, Tobias Bald, Thomas Gebhardt, Michael Hölzel

  • Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19.

    JAMA network open

    Authors: Frank L van de Veerdonk, Ilse J E Kouijzer, Aline H de Nooijer, Hans G van der Hoeven, Coen Maas, Mihai G Netea, Roger J M Brüggemann

  • Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.

    The Journal of clinical investigation

    Authors: Lina Such, Fang Zhao, Derek Liu, Beatrice Thier, Vu Thuy Khanh Le-Trilling, Antje Sucker, Christoph Coch, Natalia Pieper, Sebastian Howe, Hilal Bhat, Halime Kalkavan, Cathrin Ritter, Robin Brinkhaus, Selma Ugurel, Johannes Köster, Ulrike Seifert, Ulf Dittmer, Martin Schuler, Karl S Lang, Thomas A Kufer, Gunther Hartmann, Jürgen C Becker, Susanne Horn, Soldano Ferrone, David Liu, Eliezer M Van Allen, Dirk Schadendorf, Klaus Griewank, Mirko Trilling, Annette Paschen