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Publications

featured publications

  • Discovery of potent and selective inhibitors of human NLRP3 with a novel mechanism of action.

    The Journal of experimental medicine

    Authors: Kevin Wilhelmsen, Aditi Deshpande, Sarah Tronnes, Maitriyee Mahanta, Matthew Banicki, Mary Cochran, Samantha Cowdin, Kristen Fortney, George Hartman, Robert E Hughes, Rusty Montgomery, Claudia P Portillo, Paul Rubin, Taiz Salazar, Yan Wang, Shijun Yan, Barry A Morgan, Assem Duisembekova, Romane Riou, Michael Marleaux, Inga V Hochheiser, Hannes Buthmann, Dominic Ferber, Jane Torp, Wei Wang, Melanie Cranston, Chloe M McKee, Thea J Mawhinney, Emma C McKay, Fehime K Eroglu, Jasmin Kümmerle-Deschner, Alexander N R Weber, Bénédicte F Py, Matthias Geyer, Rebecca C Coll

  • Associations Between Structural Phenotype and Polygenic Risk Scores in Intermediate Age-Related Macular Degeneration - A MACUSTAR Report.

    Translational vision science & technology

    Authors: Lukas Schloesser, Jan H Terheyden, Charlotte Behning, Hannah Klinkhammer, Davide Garzone, Marlene Saßmannshausen, Sarah Thiele, Steffen Schmitz-Valckenberg, Carel Hoyng, Clara I Sánchez, Matthias Schmid, Ulrich F O Luhmann, Heather Floyd, Sergio Leal, Frank G Holz, Robert P Finger

  • Chronification of metastatic leiomyosarcoma in 9 lines of therapy by precision oncology: a case report and review of the literature.

    Frontiers in oncology

    Authors: Christian R Klein, Sebastian Koob, Verena Tischler, Annkristin Heine, Peter Brossart, Georg Feldmann, Karin Mayer

  • Maladaptive trained immunity in viral infections.

    The Journal of clinical investigation

    Authors: Dmitri Sviridov, Mihai G Netea, Michael I Bukrinsky

  • The RNA-binding protein TRIM71 is essential for hearing in humans and mice and times auditory sensory organ development.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Xiao-Jun Li, Charles Morgan, Phan Q Duy, Lale Evsen, Le T Hao, Roxane Machavoine, Kahina Belhous, Sylvain Ernest, Françoise Denoyelle, Cyril Mignot, Frederic Brioude, Marine Parodi, Lin Li, He Huang, Prathamesh T Nadar Ponniah, Waldemar Kolanus, Kristopher T Kahle, Sandrine Marlin, Angelika Doetzlhofer

  • AhR signaling in skin-resident CD207 cells is involved in UV-B-induced amelioration of neuroinflammation.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Nadine Mykicki, Johannes A Eble, Heike Weighardt, Elena Gonnelli, Maria Schneeweiß, Charlotte Esser, Carsten Weishaupt, Maryam Rezaei, Irmgard Förster, Nicholas Schwab, Heinz Wiendl, Björn E Clausen, Sven G Meuth, Karin Loser

  • Anxiety in Myasthenia Gravis Patients Throughout the COVID-19 Pandemic-Prevalence, Risk Factors, and Association With Vaccination Status.

    Brain and behavior

    Authors: Janna Beckmann, Moritz Petzold, Felix Betzler, Andreas Ströhle, Antonia Bendau, Carla Dusemund, Gabor C Petzold, Andreas Meisel, Sarah Hoffmann

  • Efficient Expression and Purification of Recombinant Mouse Dimeric IgA.

    European journal of immunology

    Authors: Antonia Geisse, Tao Zhang, Jonathan Schreiber, Kristina Markova, Sophie Burkhalter, Hedda Wardemann, Andrew J Macpherson, Tim Rollenske

  • Replication of blood DNA methylomic signatures associated with cerebrospinal fluid levels of YKL-40 and NfL biomarkers.

    Alzheimer's & dementia : the journal of the Alzheimer's Association

    Authors: Timo Kaleck, Rafael Campos-Martin, Amanda Cano, Maria Victoria Fernández, Pamela Martino-Adami, Luca Kleineidam, Victor M Andrade Fuentes, Kumar P Tripathi, Kayenat Parveen, Raquel Puerta, Itziar de Rojas, Kishore A Ravichandran, Oliver Peters, Julian Hellmann-Regen, Josef Priller, Maria Gemenetzi, Anja Schneider, Jens Wiltfang, Emrah Düzel, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Frederic Brosseron, Marta Marquié, Daniel LA van den Hove, Mercè Boada, Michael T Heneka, Michael Wagner, Natalie Marchant, Jean-Charles Lambert, Ruth Frikke-Schmidt, Frank Jessen, Agustín Ruiz, Alfredo Ramirez

  • TROP-2 overexpression in papillary renal cell carcinoma supports its potential as a therapeutic target for antibody-drug-conjugate therapy.

    World journal of urology

    Authors: Carolina Kessler, Melanie von Brandenstein, Niklas Klümper, Philipp Krausewitz, Enno Storz, Constantin Rieger, Laurenz Sperber, Pia Paffenholz, Yuri Tolkach, Ralph Wirtz, Markus Eckstein, Axel Heidenreich, Richard Weiten