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featured publications

  • Immunoengineering of a Photocaged 5´-triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG-I Activation in Cancer.

    Angewandte Chemie (International ed. in English)

    Authors: Sandra Lewash, Vivien McKenney, Christine Wuebben, Janos Ludwig, Racha Hosni, Dirk Radzey, Marieta Toma, Martin Schlee, Eva Bartok, Thomas Zillinger, Alexander Heckel, Gunther Hartmann

  • Disease stage-specific atrophy markers in Alzheimer's disease.

    medRxiv : the preprint server for health sciences

    Authors: Hannah Baumeister, Helena M Gellersen, Sarah E Polk, René Lattmann, Anika Wuestefeld, Laura E M Wisse, Trevor Glenn, Renat Yakupov, Melina Stark, Luca Kleineidam, Sandra Roeske, Barbara Marcos Morgado, Hermann Esselmann, Frederic Brosseron, Alfredo Ramirez, Falk Lüsebrink, Matthis Synofzik, Björn H Schott, Matthias C Schmid, Stefan Hetzer, Peter Dechent, Klaus Scheffler, Michael Ewers, Julian Hellmann-Regen, Ersin Ersözlü, Eike Spruth, Maria Gemenetzi, Klaus Fliessbach, Claudia Bartels, Ayda Rostamzadeh, Wenzel Glanz, Enise I Incesoy, Daniel Janowitz, Boris-Stephan Rauchmann, Ingo Kilimann, Sebastian Sodenkamp, Marie Coenjaerts, Annika Spottke, Oliver Peters, Josef Priller, Anja Schneider, Jens Wiltfang, Katharina Buerger, Robert Perneczky, Stefan Teipel, Christoph Laske, Michael Wagner, Gabriel Ziegler, Frank Jessen, Emrah Düzel, David Berron

  • Evaluating Sorafenib (SORA-2) as Second-Line Treatment for Unresectable Hepatocellular Carcinoma: A European Retrospective Multicenter Study.

    Cancers

    Authors: Christian Möhring, Moritz Berger, Farsaneh Sadeghlar, Xin Zhou, Taotao Zhou, Malte Benedikt Monin, Kateryna Shmanko, Sabrina Welland, Friedrich Sinner, Birgit Schwacha-Eipper, Ulrike Bauer, Christoph Roderburg, Angelo Pirozzi, Najib Ben Khaled, Peter Schrammen, Lorenz Balcar, Matthias Pinter, Thomas J Ettrich, Anna Saborowski, Marie-Luise Berres, Enrico N De Toni, Tom Lüdde, Lorenza Rimassa, Ursula Ehmer, Marino Venerito, Iuliana-Pompilia Radu, Ingo G H Schmidt-Wolf, Arndt Weinmann, Arndt Vogel, Matthias Schmid, Jörg C Kalff, Christian P Strassburg, Maria A Gonzalez-Carmona

  • A versatile toolbox for determining IRES activity in cells and embryonic tissues.

    The EMBO journal

    Authors: Philipp Koch, Zijian Zhang, Naomi R Genuth, Teodorus Theo Susanto, Martin Haimann, Alena Khmelinskaia, Gun Woo Byeon, Saurabh Dey, Maria Barna, Kathrin Leppek

  • Immune training enhances anti-viral responses and improves outcomes in Pax5 mice susceptible to chronic infection.

    EMBO molecular medicine

    Authors: Zhe Lu, Olivia Stencel, Wei Liu, Eleni Vasileiou, Haifeng C Xu, Piyush Pandey, Paweł Stachura, Abdelrahman Elwy, Anastassia Tsombal, Ann-Sophie Mai, Franziska Auer, Mina N F Morcos, Maximilian Seidl, Sarah Koziel, Peter-Martin Bruch, Sascha Dietrich, Sarah Elitzur, Gunther Hartmann, Karl S Lang, Stefan Janssen, Ute Fischer, Sanil Bhatia, Philipp A Lang, Arndt Borkhardt, Julia Hauer, Aleksandra A Pandyra

  • Light-activatable photochemically targeting chimeras (PHOTACs) enable the optical control of targeted protein degradation of HDAC6.

    RSC medicinal chemistry

    Authors: Silas L Wurnig, Maria Hanl, Thomas M Geiger, Shiyang Zhai, Ina Dressel, Dominika E Pieńkowska, Radosław P Nowak, Finn K Hansen

  • The DNase TREX1 is a substrate of the intramembrane protease SPP with implications for disease pathogenesis.

    Cellular and molecular life sciences : CMLS

    Authors: Onur Kerem Tever, Torben Mentrup, Ivan Kingyue Chinn, Hitoshi Ishikuma, Regina Fluhrer, Marc Schmitz, Rebekka Wehner, Rayk Behrendt, Javier Chinen, Bernd Schröder

  • A functional single-cell metabolic survey identifies Elovl1 as a target to enhance CD8 T cell fitness in solid tumours.

    Nature metabolism

    Authors: Samantha Pretto, Qian Yu, Pierre Bourdely, Sarah Trusso Cafarello, Heleen H Van Acker, Joren Verelst, Elena Richiardone, Lotte Vanheer, Amir Roshanzadeh, Franziska Schneppenheim, Charlotte Cresens, Maria Livia Sassano, Jonas Dehairs, Martin Carion, Shehab Ismail, Patrizia Agostinis, Susana Rocha, Tobias Bald, Johan Swinnen, Cyril Corbet, Sophia Y Lunt, Bernard Thienpont, Mario Di Matteo, Massimiliano Mazzone

  • DataSHIELD: mitigating disclosure risk in a multi-site federated analysis platform.

    Bioinformatics advances

    Authors: Demetris Avraam, Rebecca C Wilson, Noemi Aguirre Chan, Soumya Banerjee, Tom R P Bishop, Olly Butters, Tim Cadman, Luise Cederkvist, Liesbeth Duijts, Xavier Escribà Montagut, Hugh Garner, Gonçalo Gonçalves, Juan R González, Sido Haakma, Mette Hartlev, Jan Hasenauer, Manuel Huth, Eleanor Hyde, Vincent W V Jaddoe, Yannick Marcon, Michaela Th Mayrhofer, Fruzsina Molnar-Gabor, Andrei Scott Morgan, Madeleine Murtagh, Marc Nestor, Anne-Marie Nybo Andersen, Simon Parker, Angela Pinot de Moira, Florian Schwarz, Katrine Strandberg-Larsen, Morris A Swertz, Marieke Welten, Stuart Wheater, Paul Burton

  • Unveiling IRF4-steered regulation of context-dependent effector programs in CD4 T cells under Th17- and Treg-skewing conditions.

    Cell reports

    Authors: Anna Gabele, Maximilian Sprang, Mert Cihan, Mareen Welzel, Assel Nurbekova, Karolina Romaniuk, Sarah Dietzen, Matthias Klein, Georg Bündgen, Maxim Emelianov, Gregory Harms, Krishnaraj Rajalingam, Tanja Ziesmann, Katrin Pape, Beatrice Wasser, David Gomez-Zepeda, Kathrin Braband, Michael Delacher, Niels Lemmermann, Stefan Bittner, Miguel A Andrade-Navarro, Stefan Tenzer, Katja Luck, Tobias Bopp, Ute Distler