Skip to main content

Publications

Featured publications

  • Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis.

    EBioMedicine

    Authors: Yvonn Heun, Joachim Pircher, Thomas Czermak, Philipp Bluem, Georg Hupel, Monica Bohmer, Bjoern F Kraemer, Kristin Pogoda, Alexander Pfeifer, Markus Woernle, Andrea Ribeiro, Max Hübner, Simone Kreth, Ralf A Claus, Sebastian Weis, Luisa Ungelenk, Florian Krötz, Ulrich Pohl, Hanna Mannell

  • The pentaglycine bridges of Staphylococcus aureus peptidoglycan are essential for cell integrity.

    Scientific reports

    Authors: João M Monteiro, Gonçalo Covas, Daniela Rausch, Sérgio R Filipe, Tanja Schneider, Hans-Georg Sahl, Mariana G Pinho

  • Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model.

    Scientific reports

    Authors: Laia Civit, Ioanna Theodorou, Franziska Frey, Holger Weber, Andreas Lingnau, Carsten Gröber, Michael Blank, Chloé Dambrune, James Stunden, Marc Beyer, Joachim Schultze, Eicke Latz, Frédéric Ducongé, Michael H G Kubbutat, Günter Mayer

  • The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

    Molecular psychiatry

    Authors: Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Goate, Celeste M Karch, Anne M Fagan, Eric McDade, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Marc Suárez-Calvet, Christian Haass, Brian A Gordon, Yen Ying Lim, Colin L Masters, Daniel Janowitz, Cihan Catak, Steffen Wolfsgruber, Michael Wagner, Esther Milz, Sonia Moreno-Grau, Stefan Teipel, Michel J Grothe, Ingo Kilimann, Martin Rossor, Nick Fox, Christoph Laske, Jasmeer Chhatwal, Peter Falkai, Robert Perneczky, Jae-Hong Lee, Annika Spottke, Henning Boecker, Frederic Brosseron, Klaus Fliessbach, Michael T Heneka, Peter Nestor, Oliver Peters, Manuel Fuentes, Felix Menne, Josef Priller, Eike J Spruth, Christiana Franke, Anja Schneider, Christine Westerteicher, Oliver Speck, Jens Wiltfang, Claudia Bartels, Miguel Ángel Araque Caballero, Coraline Metzger, Daniel Bittner, Stephen Salloway, Adrian Danek, Jason Hassenstab, Igor Yakushev, Peter R Schofield, John C Morris, Randall J Bateman, Michael Ewers

  • Optogenetic stimulation of G-signaling in the heart with high spatio-temporal precision.

    Nature communications

    Authors: Philipp Makowka, Tobias Bruegmann, Vanessa Dusend, Daniela Malan, Thomas Beiert, Michael Hesse, Bernd K Fleischmann, Philipp Sasse

  • The tricyclic antidepressant clomipramine inhibits neuronal autophagic flux.

    Scientific reports

    Authors: Federica Cavaliere, Alessandra Fornarelli, Fabio Bertan, Rossella Russo, Anaïs Marsal-Cots, Luigi Antonio Morrone, Annagrazia Adornetto, Maria Tiziana Corasaniti, Daniele Bano, Giacinto Bagetta, Pierluigi Nicotera

  • Direct targeting of Gα and Gα oncoproteins in cancer cells.

    Science signaling

    Authors: Suvi Annala, Xiaodong Feng, Naveen Shridhar, Funda Eryilmaz, Julian Patt, JuHee Yang, Eva M Pfeil, Rodolfo Daniel Cervantes-Villagrana, Asuka Inoue, Felix Häberlein, Tanja Slodczyk, Raphael Reher, Stefan Kehraus, Stefania Monteleone, Ramona Schrage, Nina Heycke, Ulrike Rick, Sandra Engel, Alexander Pfeifer, Peter Kolb, Gabriele König, Moritz Bünemann, Thomas Tüting, José Vázquez-Prado, J Silvio Gutkind, Evelyn Gaffal, Evi Kostenis

  • Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.

    Nature cell biology

    Authors: Camilla Salvagno, Metamia Ciampricotti, Sander Tuit, Cheei-Sing Hau, Antoinette van Weverwijk, Seth B Coffelt, Kelly Kersten, Kim Vrijland, Kevin Kos, Thomas Ulas, Ji-Ying Song, Chia-Huey Ooi, Dominik Rüttinger, Philippe A Cassier, Jos Jonkers, Joachim L Schultze, Carola H Ries, Karin E de Visser

  • Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

    Kidney international

    Authors: Victor G Puelles, David Fleck, Lena Ortz, Stella Papadouri, Thiago Strieder, Alexander M C Böhner, James W van der Wolde, Michael Vogt, Turgay Saritas, Christoph Kuppe, Astrid Fuss, Sylvia Menzel, Barbara M Klinkhammer, Gerhard Müller-Newen, Felix Heymann, Leon Decker, Fabian Braun, Oliver Kretz, Tobias B Huber, Etsuo A Susaki, Hiroki R Ueda, Peter Boor, Jürgen Floege, Rafael Kramann, Christian Kurts, John F Bertram, Marc Spehr, David J Nikolic-Paterson, Marcus J Moeller

  • LipidII interaction with specific residues of Mycobacterium tuberculosis PknB extracytoplasmic domain governs its optimal activation.

    Nature communications

    Authors: Prabhjot Kaur, Marvin Rausch, Basanti Malakar, Uchenna Watson, Nikhil P Damle, Yogesh Chawla, Sandhya Srinivasan, Kanika Sharma, Tanja Schneider, Gagan Deep Jhingan, Deepak Saini, Debasisa Mohanty, Fabian Grein, Vinay Kumar Nandicoori