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featured publications

  • AI-Guided Additive Scoring Model for Differential Diagnosis of Primary Liver Cancer.

    JHEP reports : innovation in hepatology

    Authors: Rebekka J S Salzmann, Tudor Mocan, Arnulf G Willms, Angelina Klein, Robert Schwab, Emil Mois, Cristiana Grapa, Lavinia Patricia Mocan, Rares Craciun, Zeno Sparchez, Ingo G H Schmidt-Wolf, Jan Best, Hartmut H Schmidt, Marcin Krawczyk, Simon C Robson, Veronika Lukacs-Kornek, Miroslaw T Kornek

  • Pathogenic GM-CSF drives functional diversification of inflammatory macrophages in autoimmune arthritis.

    Science advances

    Authors: Hiroki Mukoyama, Yusuke Takeuchi, Daiya Ohara, Yoonha Lee, Hitomi Watanabe, Hiroki Kato, Gen Kondoh, Akio Morinobu, Keiji Hirota

  • Suggested experimental design and computational modeling to infer single-cell lipid dynamics from a single destructive measurement.

    iScience

    Authors: Paul Jonas Jost, Daniel Weindl, Klaus Wunderling, Christoph Thiele, Jan Hasenauer

  • Polygenic, cell-envelope adaptations drive high-frequency daptomycin resistance in NRCS-A from neonatal sepsis and NEC.

    Antimicrobial agents and chemotherapy

    Authors: Lara Kränkel, Janna Hauser, Jessica Slavetinsky, Alina Zinser, Annika Schmidt, Mulugeta Nega, Ahmed M A Elsherbini, Tanja Schneider, Christian Gille, Martin Schaller, Jörg Fuchs, Andreas Peschel, Christoph Slavetinsky

  • Early clinical recovery in STEMI cardiogenic shock: insights from the DanGer shock trial.

    European heart journal. Acute cardiovascular care

    Authors: Rasmus Paulin Beske, Anika Klein, Lisette Okkels Jensen, Hans Eiskjær, Norman Mangner, Amin Polzin, P Christian Schulze, Carsten Skurk, Peter Nordbeck, Benedikt Schrage, Vasileios Panoulas, Sebastian Zimmer, Andreas Schäfer, Christian Hassager, Jacob Eifer Møller

  • Mast cell activation within the mesentery depends on vagal signaling following abdominal surgery.

    Surgery open science

    Authors: Anna Woestemeier, Timo Schwandt, Philipp Lingohr, Mariola Lysson, Sven Wehner, Jörg C Kalff, Gun-Soo Hong

  • Tissue-restricted secondary TCR engagement drives the transition from stem-like to CD200 Egr2 arthritogenic Th17 cells.

    Nature immunology

    Authors: Yusuke Takeuchi, Daiya Ohara, Hitomi Watanabe, Yuji Nishimura, Takeshi Iwasaki, Shohei Hori, Hiroshi Kawamoto, Hiroki Kato, Gen Kondoh, Akio Morinobu, Tsuneyo Mimori, Keiji Hirota

  • Hyperreflective foci contiguous with the RPE associate with visual function in aging, early and intermediate AMD: MACUSTAR study report.

    American journal of ophthalmology

    Authors: Lukas Goerdt, Vanessa Basten, Jan H Terheyden, Hannah Dunbar, Ulrich Luhmann, Nadia Zakaria, Sergio Leal, Klaus-Peter Moll, Stephen Poor, Adnan Tufail, Matthias Schmid, Robert P Finger, Steffen Schmitz-Valckenberg, Frank G Holz, Marlene Saßmannshausen

  • Generation and characterization of a human induced pluripotent stem cell line (hiPSC) expressing the rEstus voltage sensor under doxycycline induction.

    Stem cell research

    Authors: Daniela Malan, Philipp Rühl, Stefan H Heinemann, Bernd K Fleischmann, Caroline Geisen

  • Blocking microglial reactivity via purinergic receptors prevents subacute cognitive deficits after TIA.

    EMBO molecular medicine

    Authors: Gemma Llovera, Steffanie Heindl, Daniel P Varga, Nikolett Lenart, Sebastian Kallabis, Vanessa Göb, David Stegner, Raphael Escaig, Leo Nicolai, Nicolai Franzmeier, Felix Meissner, Adam Denes, Arthur Liesz