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featured publications

  • Chronic progressive demyelination induces a microglial state with lysosomal dysfunction.

    Nature neuroscience

    Authors: Stefan A Berghoff, Lena Spieth, Simona Vitale, Lennart Schlaphoff, Martin Zirngibl, Niklas Junker, Alan-Charles Dean, Lu Liu, Alkmini Damkou, Stefan Roth, Charlene-Annett Hurler, Leon Hosang, Katrin Perez Anderson, Simon Besson-Girard, Marvin Reich, Astrid Feiten, Ludwig Huber, Christoph Müller, Georg Kislinger, Lina Dinkel, Yakum B Nkeh, Janos Groh, Anna Williams, Arthur Liesz, Martina Schifferer, Gesine Saher, Klaus-Armin Nave, Sarah Jäkel, Sabina Tahirovic, Martin Giera, Ozgun Gokce, Mikael Simons

  • Endothelial p16 expression identifies a subgroup of clear cell renal cell carcinoma with favorable prognosis.

    BMC cancer

    Authors: Michael Stoffel, Katharina Baschun, Melina Kehl, Jörg Ellinger, Niklas Klümper, Sebastian Kadzik, Franziska I Winterhagen, Manuel Ritter, Michael Hölzel, Glen Kristiansen, Marieta I Toma

  • Effect of aging on neutrophil function in humans.

    Cellular immunology

    Authors: Joelle Noriko Galang, Nicholas A Sumpter, Titus Schlüter, Nils Asmann, Laura Merlo Pich, Andrei Sarlea, Frank van de Veerdonk, Athanasios Ziogas, Mihai G Netea

  • Longitudinal analysis of structural biomarkers for disease progression in intermediate age-related macular degeneration: a MACUSTAR study report.

    Ophthalmology. Retina

    Authors: Lukas Goerdt, Danielle Bessaheken, Jan H Terheyden, Sarah Thiele, Vanessa Basten, Charlotte Behning, Ulrich Luhmann, Sergio Leal, Klaus-Peter Moll, Nadia Zakaria, Matthias Schmid, Robert P Finger, Frank G Holz, Steffen Schmitz-Valckenberg, Marlene Saßmannshausen

  • Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.

    Blood cancer journal

    Authors: Steffen Koschmieder, Susanne Isfort, Lino L Teichmann, Philippe Schafhausen, Florian H Heidel, Carl Crodel, Andreas Hochhaus, Martin Griesshammer, Katja Sockel, Philipp J Jost, Denise Walther, Konstanze Döhner, Joachim R Göthert, Markus Radsak, Marinela Augustin, Heiko Becker, Aristoteles Giagounidis, Markus Schaich, Martine Klausmann, Nikolas von Bubnoff, Frank Stegelmann, Maike Kortmann, Michelle Zentis, Julia Frank, Anna Hagemeier, Martin Hellmich, Tim H Brümmendorf

  • NanoBRET Target Engagement Enables Validation of p53 Y220C Ligands in a Cellular Context.

    Journal of medicinal chemistry

    Authors: Dominika Ewa Pieńkowska, Xijun Zhu, Nathanael S Gray, Radosław P Nowak

  • EudraScore: Modification of the Vigi4Eudra-score for the Assessment of the Completeness of Adverse Drug Reaction Reports in EudraVigilance.

    Drug safety

    Authors: Diana Dubrall, Patrick Christ, Dennis Lex, Robert Hoffmann, Thomas Grüger, Matthias Schmid, Bernhardt Sachs

  • G-quadruplex structures affect the immune response to bacterial infection in mouse macrophages.

    Nature communications

    Authors: Philipp Schult, Melanie Kastl, Jennifer Szlapa, Konstantinos Symeonidis, Salie Maasewerd, Bernardo Franklin, Alea Radcke, Stefan A Juranek, Zeinab Abdullah, Katrin Paeschke

  • Correction: Aflibercept 8 mg in neovascular age-related macular degeneration and diabetic macular oedema: Translating clinical trials into clinical practice.

    Eye (London, England)

    Authors: Sobha Sivaprasad, Michael W Stewart, Charles C Wykoff, David Eichenbaum, Jean-Francois Korobelnik, Paolo Lanzetta, Varun Chaudhary, Chui Ming Gemmy Cheung, Richard Gale, Marion R Munk, Taiji Sakamoto, Andreas Stahl, Javier Zarranz-Ventura, Tien Yin Wong, Frank G Holz, Anat Loewenstein

  • New insights into takotsubo syndrome: results from a multicenter cohort.

    Clinical research in cardiology : official journal of the German Cardiac Society

    Authors: Hugo Lanz, Endrit Cekaj, Lucas Bacmeister, Christian Jung, Samuel Muli, Sabine Hoffmann, Matthias Schmid, Marcelo Galdos-Bejar, Daniel Hoyer, Lisa Crusius, Norman Mangner, Lisa Reinhardt, Loubna Yahsaly, Lars Michel, Victoria Pfeiffer, Mostafa Salem, Rafael Henrique Rangel, Johannes Terporten, Fabian Heindl, Marcus Brugger, Sebastian Zimmer, Tienush Rassaf, David Leistner, Dirk Westermann, Benjamin Meder, Malte Kelm, Stephan Baldus, Christian Schulze, Georg Nickenig, Franz Haertel, Enzo Lüsebrink