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featured publications

  • Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium.

    Scientific reports

    Authors: Jose M Sánchez-Maldonado, Rafael Cáliz, Luz Canet, Rob Ter Horst, Olivier Bakker, Alfons A den Broeder, Manuel Martínez-Bueno, Helena Canhão, Ana Rodríguez-Ramos, Carmen B Lupiañez, María José Soto-Pino, Antonio García, Eva Pérez-Pampin, Alfonso González-Utrilla, Alejandro Escudero, Juana Segura-Catena, Romana T Netea-Maier, Miguel Ángel Ferrer, Eduardo Collantes-Estevez, Miguel Ángel López Nevot, Yang Li, Manuel Jurado, João E Fonseca, Mihai G Netea, Marieke J H Coenen, Juan Sainz

  • β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32.

    Cell reports

    Authors: Jéssica Cristina Dos Santos, Ana Marina Barroso de Figueiredo, Muriel Vilela Teodoro Silva, Branko Cirovic, L Charlotte J de Bree, Michelle S M A Damen, Simone J C F M Moorlag, Rodrigo S Gomes, Monique M Helsen, Marije Oosting, Samuel T Keating, A Schlitzer, Mihai G Netea, Fátima Ribeiro-Dias, Leo A B Joosten

  • Targeting innate immunity for tuberculosis vaccination.

    The Journal of clinical investigation

    Authors: Shabaana A Khader, Maziar Divangahi, Willem Hanekom, Philip C Hill, Markus Maeurer, Karen W Makar, Katrin D Mayer-Barber, Musa M Mhlanga, Elisa Nemes, Larry S Schlesinger, Reinout van Crevel, Raman (Krishna) Vankayalapati, Ramnik J Xavier, Mihai G Netea

  • Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells.

    Nature communications

    Authors: Noa Bossel Ben-Moshe, Shelly Hen-Avivi, Natalia Levitin, Dror Yehezkel, Marije Oosting, Leo A B Joosten, Mihai G Netea, Roi Avraham

  • Immunometabolism orchestrates training of innate immunity in atherosclerosis.

    Cardiovascular research

    Authors: Julia van Tuijl, Leo A B Joosten, Mihai G Netea, Siroon Bekkering, Niels P Riksen

  • Therapeutic targeting of trained immunity.

    Nature reviews. Drug discovery

    Authors: Willem J M Mulder, Jordi Ochando, Leo A B Joosten, Zahi A Fayad, Mihai G Netea

  • Itaconate as an immune modulator.

    Aging

    Authors: Anaísa V Ferreira, Mihai G Netea, Jorge Domínguez-Andrés

  • Bromodomain inhibitor I-BET151 suppresses immune responses during fungal-immune interaction.

    European journal of immunology

    Authors: Jorge Domínguez-Andrés, Anaísa V Ferreira, Trees Jansen, Nicholas Smithers, Rab K Prinjha, Rebecca C Furze, Mihai G Netea

  • Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration.

    Cellular oncology (Dordrecht)

    Authors: Yvette J E Sloot, Katrin Rabold, Thomas Ulas, Dennis M De Graaf, Bas Heinhuis, Kristian Händler, Joachim L Schultze, Mihai G Netea, Johannes W A Smit, Leo A B Joosten, Romana T Netea-Maier

  • Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.

    Cell metabolism

    Authors: Siroon Bekkering, Lotte C A Stiekema, Sophie Bernelot Moens, Simone L Verweij, Boris Novakovic, Koen Prange, Miranda Versloot, Jeanine E Roeters van Lennep, Henk Stunnenberg, Menno de Winther, Erik S G Stroes, Leo A B Joosten, Mihai G Netea, Niels P Riksen