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featured publications

  • Insights into reproduction-regulating NOD-like receptors.

    Nature structural & molecular biology

    Authors: Inga V Hochheiser, Matthias Geyer

  • The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma.

    Scientific reports

    Authors: Michael Praktiknjo, Ana S Pena Solano, Farsaneh Sadeghlar, Thomas Welchowski, Matthias Schmid, Christian Möhring, Taotao Zhou, Robert Mahn, Malte B Monin, Carsten Meyer, Georg Feldmann, Peter Brossart, Cornelius van Beekum, Alexander Semaan, Hanno Matthaei, Steffen Manekeller, Alois M Sprinkart, Sebastian Nowak, Julian Luetkens, Jörg C Kalff, Christian P Strassburg, Maria A González-Carmona

  • Clinical and Market Analysis of NanoBEO: A Public-Worth, Innovative Therapy for Behavioral and Psychological Symptoms of Dementia (BPSD)-Emerging Evidence and Its Implications for a Health Technology Assessment (HTA) and Decision-Making in National …

    Pharmaceutics

    Authors: Damiana Scuteri, Daniele Pierobon, Martina Pagliaro, Kengo Hamamura, Takafumi Hayashi, Loris Pignolo, Pierluigi Nicotera, Giacinto Bagetta, Maria Tiziana Corasaniti

  • Gene Therapy with Fidanacogene Elaparvovec in Adults with Hemophilia B.

    The New England journal of medicine

    Authors: Adam Cuker, Kaan Kavakli, Laurent Frenzel, Jiaan-Der Wang, Jan Astermark, Monica H Cerqueira, Alfonso Iorio, Olga Katsarou-Fasouli, Robert Klamroth, Amy D Shapiro, Cédric Hermans, Akira Ishiguro, Andrew D Leavitt, Johannes B Oldenburg, Margareth C Ozelo, Jerome Teitel, Francesca Biondo, Annie Fang, Joanne Fuiman, John McKay, Pengling Sun, John E J Rasko, Jeremy Rupon

  • Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application.

    Nature communications

    Authors: Lisa D J Schiffelers, Yonas M Tesfamariam, Lea-Marie Jenster, Stefan Diehl, Sophie C Binder, Sabine Normann, Jonathan Mayr, Steffen Pritzl, Elena Hagelauer, Anja Kopp, Assaf Alon, Matthias Geyer, Hidde L Ploegh, Florian I Schmidt

  • Interleukin-1β induces trained innate immunity in human hematopoietic progenitor cells in vitro.

    Stem cell reports

    Authors: Daniela Flores-Gomez, Willemijn Hobo, Diede van Ens, Elise L Kessler, Boris Novakovic, Nicolaas P M Schaap, Wim H C Rijnen, Leo A B Joosten, Mihai G Netea, Niels P Riksen, Siroon Bekkering

  • Neuroprotective Effect of Melatonin in a Neonatal Hypoxia-Ischemia Rat Model Is Regulated by the AMPK/mTOR Pathway.

    Journal of the American Heart Association

    Authors: Efe Nacarkucuk, Maria E Bernis, Anna-Sophie Bremer, Kora Grzelak, Margit Zweyer, Elke Maes, Hannah Burkard, Hemmen Sabir

  • Polymorphisms within autophagy-related genes as susceptibility biomarkers for pancreatic cancer: A meta-analysis of three large European cohorts and functional characterization.

    International journal of cancer

    Authors: Fernando Gálvez-Montosa, Giulia Peduzzi, José Manuel Sanchez-Maldonado, Rob Ter Horst, Antonio J Cabrera-Serrano, Manuel Gentiluomo, Angelica Macauda, Natalia Luque, Pelin Ünal, Francisco Javier García-Verdejo, Yang Li, José Antonio López López, Angelika Stein, H Bas Bueno-de-Mesquita, Paolo Giorgio Arcidiacono, Dalila Luciola Zanette, Christoph Kahlert, Francesco Perri, Pavel Soucek, Renata Talar-Wojnarowska, George E Theodoropoulos, Jakob R Izbicki, Hussein Tamás, Hanneke Van Laarhoven, Gennaro Nappo, Maria Chiara Petrone, Martin Lovecek, Roel C H Vermeulen, Kestutis Adamonis, Fernando Jesus Reyes-Zurita, Bernd Holleczek, Jolanta Sumskiene, Beatrice Mohelníková-Duchoňová, Rita T Lawlor, Raffaele Pezzilli, Mateus Nobrega Aoki, Claudio Pasquali, Vitalija Petrenkiene, Daniela Basso, Stefania Bunduc, Annalisa Comandatore, Hermann Brenner, Stefano Ermini, Giuseppe Vanella, Mara R Goetz, Livia Archibugi, Maurizio Lucchesi, Faik Guntac Uzunoglu, Olivier Busch, Anna Caterina Milanetto, Marta Puzzono, Juozas Kupcinskas, Luca Morelli, Cosimo Sperti, Silvia Carrara, Gabriele Capurso, Casper H J van Eijck, Martin Oliverius, Susanne Roth, Francesca Tavano, Rudolf Kaaks, Andrea Szentesi, Ludmila Vodickova, Claudio Luchini, Ben Schöttker, Stefano Landi, Orsolya Dohan, Matteo Tacelli, William Greenhalf, Maria Gazouli, John P Neoptolemos, Giulia Martina Cavestro, Ugo Boggi, Anna Latiano, Péter Hegyi, Laura Ginocchi, Mihai G Netea, Pedro Sánchez-Rovira, Federico Canzian, Daniele Campa, Juan Sainz

  • Association of ultra-processed foods intake with untargeted metabolomics profiles in adolescents and young adults in the DONALD cohort study.

    The Journal of nutrition

    Authors: Samuel Muli, Annika Blumenthal, Christina-Alexandra Conzen, Maike Elena Benz, Ute Alexy, Matthias Schmid, Pekka Keski-Rahkonen, Anna Floegel, Ute Nöthlings

  • Common variants increase risk for congenital diaphragmatic hernia within the context of de novo variants.

    American journal of human genetics

    Authors: Lu Qiao, Carrie L Welch, Rebecca Hernan, Julia Wynn, Usha S Krishnan, Jill M Zalieckas, Terry Buchmiller, Julie Khlevner, Aliva De, Christiana Farkouh-Karoleski, Amy J Wagner, Andreas Heydweiller, Andreas C Mueller, Annelies de Klein, Brad W Warner, Carlo Maj, Dai Chung, David J McCulley, David Schindel, Douglas Potoka, Elizabeth Fialkowski, Felicitas Schulz, Florian Kipfmuller, Foong-Yen Lim, Frank Magielsen, George B Mychaliska, Gudrun Aspelund, Heiko Martin Reutter, Howard Needelman, J Marco Schnater, Jason C Fisher, Kenneth Azarow, Mahmoud Elfiky, Markus M Nöthen, Melissa E Danko, Mindy Li, Przemyslaw Kosiński, Rene M H Wijnen, Robert A Cusick, Samuel Z Soffer, Suzan C M Cochius-Den Otter, Thomas Schaible, Timothy Crombleholme, Vincent P Duron, Patricia K Donahoe, Xin Sun, Frances A High, Charlotte Bendixen, Erwin Brosens, Yufeng Shen, Wendy K Chung