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  • TALON phase IIIb study: 64 week results of brolucizumab versus aflibercept using treat-and-extend for neovascular age-related macular degeneration.

    Eye (London, England)

    Authors: Carl Regillo, Peter K Kaiser, Peter J Kertes, Mark Gillies, Tina Maio-Twofoot, David Lawrence, Frank G Holz

  • Serum-free differentiation platform for the generation of B lymphocytes and natural killer cells from human CD34+ cord blood progenitors.

    Scientific reports

    Authors: Rigveda Bhave, Carla-Johanna Kath, Nadine Rüchel, Eleni Vasileiou, Vera H Jepsen, Katharina Raba, Aleksandra A Pandyra, Ute Fischer, Gesine Kogler

  • Longitudinal Monitoring of Brain Volume Changes After COVID-19 Infection Using Artificial Intelligence-Based MRI Volumetry.

    Diagnostics (Basel, Switzerland)

    Authors: Zeynep Bendella, Catherine Nichols Widmann, Christine Kindler, Robert Haase, Malte Sauer, Michael T Heneka, Alexander Radbruch, Frederic Carsten Schmeel

  • Targeting the tumor cell-intrinsic ITGB2 axis inhibits melanoma progression.

    Molecular cancer

    Authors: Erik Rasbach, Laure Migayron, Anne Brandenburg, Praveen Singh, Christina Martins, Ali Kassem, Anastasia I Karkempetzaki, Nadine Suessner, Zsofi Kulcsar, Jessica Riopedre, Mariana Silva, Ethan Zhen, Shuyun Xu, Kyla Mucciarone, Julia Holzgruber, Jason B Williams, Emrullah Birgin, Mitchell P Levesque, Julia M Martínez-Gómez, Reinhard Dummer, Jennifer Landsberg, Christine G Lian, George F Murphy, Emma L Berdan, Shannan Ho Sui, Thomas S Kupper, Nuh N Rahbari, Nayoung Lee, Steven R Barthel, Tobias Schatton

  • Patient-Derived Monoclonal Myelin Oligodendrocyte Glycoprotein Autoantibodies Mediate Cytotoxicity.

    Neurology(R) neuroimmunology & neuroinflammation

    Authors: Nora Sandrine Wetzel, Laila Kulsvehagen, Anne-Catherine Lecourt, Beata Filipek, Patrick Lipps, Laura Rieder, Kristina Berve, Gurumoorthy Krishnamoorthy, Bert A 't Hart, Lucas Schirmer, Soumya S Yandamuri, Kevin C O'Connor, Anne-Katrin Pröbstel

  • Induction of trained immunity in myeloid cells and their progenitors from thyroid cancer patients.

    Frontiers in immunology

    Authors: Pepijn van Houten, Prashant Changoer, Liesbeth van Emst, Han J Bonenkamp, Johannes H W de Wilt, Willemijn Hobo, Manita E J Bremmers, Mieke W H Roeven, Janneke E W Walraven, Petronella B Ottevanger, Willem J M Mulder, Mihai G Netea, Martin Jaeger, Romana T Netea-Maier

  • Myeloperoxidase aggravates thoracic aortic aneurysm formation in Marfan disease.

    Cardiovascular research

    Authors: Dennis Mehrkens, Johannes Dohr, Felix Sebastian Nettersheim, Felix Ballmann, Jil Bastigkeit, Alexander Brückner, Simon Geissen, Lauren De Vore, Cedric Fitsch, Chris Diekmann, Andrea de la Fuente-Alonso, Patrik Schelemei, Felix Ruben Picard, Malte Kochen, Per Arkenberg, Anna Rappenecker, Maysam Ahdab, Harshal Nemade, Suchitra Narayan, Simon Braumann, Wiebke Kreuzberg, Alexander Hof, Henning Guthoff, Benedicta Quaye Mensah, Sebastian Lechner, Andrea Guala, Artur Evangelista, Gisela Teixido-Tura, J Francisco Nistal, Miguel R Campanero, Harald Kaemmerer, Zsuzsanna Wolf, Stefan Holdenrieder, Maarten Groenink, Mitzi van Andel, Arnout Mieremet, Susanne Pfeiler, Norbert Gerdes, Ulrich Flögel, Laura-Maria Zimmermann, Gerhard Sengle, Marie-Lisa Eich, Birgid Schömig-Markiefka, Matti Adam, Bernd K Fleischmann, Daniela Wenzel, Juan Miguel Redondo, Vivian de Waard, Anna Klinke, Stephan Baldus, Martin Mollenhauer, Holger Winkels

  • TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis.

    Nature communications

    Authors: Massimo Vetralla, Lena Wischhof, Asrat Kahsay, Vanessa Cadenelli, Enzo Scifo, Beijia Xie, Miriana Sbrissa, Maëlle Sandhira Habert, Dan Ehninger, Rosario Rizzuto, Daniele Bano, Diego De Stefani

  • An improved porcine model of infrarenal abdominal aortic aneurysm.

    Scientific reports

    Authors: Marta Stei, Per Arkenberg, Theresa Uebing, Agnesa Mazrekaj, Joscha Mulorz, Dennis Mehrkens, Maysam Ahdab, Philipp Barnowski, Gerhard Sengle, Matti Adam, Valerie Lohner, Verena Hoerr, Ali Nahardani, Claudia Schubert-Quecke, Birgitta Mewes, Johannes Lindemeyer, Holger Grüll, Albert Busch, Sebastian Zimmer, Holger Winkels, Hubert Schelzig, Malte Kelm, Georg Nickenig, Stephan Baldus, Markus U Wagenhäuser, Martin Mollenhauer

  • A 20-amino-acid Cardiovirus protein exhibits cytokine-mimicry activity to regulate viral replication.

    Cell reports

    Authors: Yutaro Shirasaka, Fumihiko Takeuchi, Satoshi Koike, Hiroki Kato, Takashi Fujita