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featured publications

  • TCA metabolism regulates DNA hypermethylation in LPS and -induced immune tolerance.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Abhimanyu, Santiago Carrero Longlax, Tomoki Nishiguchi, Malik Ladki, Daanish Sheikh, Amera L Martinez, Emily M Mace, Sandra L Grimm, Thaleia Caldwell, Alexandra Portillo Varela, Rajagopal V Sekhar, Anna M Mandalakas, Mandla Mlotshwa, Sibuse Ginidza, Jeffrey D Cirillo, Robert S Wallis, Mihai G Netea, Reinout van Crevel, Cristian Coarfa, Andrew R DiNardo

  • Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis.

    The Journal of infection

    Authors: Muhammed D Aksu, Tijmen van der Ent, Zhenhua Zhang, Anca L Riza, Aline H de Nooijer, Isis Ricaño-Ponce, Nico Janssen, Job J Engel, Ioana Streata, Helga Dijkstra, Heidi Lemmers, Inge Grondman, Valerie A C M Koeken, Eleni Antoniadou, Nikolaos Antonakos, Frank L van de Veerdonk, Yang Li, Evangelos J Giamarellos-Bourboulis, Mihai G Netea, Athanasios Ziogas

  • Interleukin 38 reduces antigen-presentation capacity and antibody production after vaccination.

    Vaccine

    Authors: Lisa U Teufel, Esther J M Taks, Jelle van Gemert, Mihaela Neacsu, Konstantin Föhse, Joshua Gillard, Dimitri A Diavatopoulos, Marien I de Jonge, Mihai G Netea, Leo A B Joosten, Rob J W Arts

  • Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B.

    Journal of medicinal chemistry

    Authors: Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland Smith, L Emilia Basantes, Katharina Schwandt, Aaron Babendreyer, Timothy Chavez, Nicholas McKee, Vijay Gokhale, Sebastian Kallabis, Felix Meissner, Samantha N Rokey, Travis Dunckley, William R Montfort, Walter Becker, Christopher Hulme

  • Transient MRI changes and neurological deterioration in glioblastoma upon SARS-CoV-2 infection.

    Journal of cancer research and clinical oncology

    Authors: Thomas Zeyen, Lea L Friker, Daniel Paech, Niklas Schaefer, Johannes Weller, Valentina Zschernack, Julian P Layer, Matthias Schneider, Anna-Laura Potthoff, Marit Bernhardt, Christine Sanders, Glen Kristiansen, Michael Hoelzel, Eleni Gkika, Alexander Radbruch, Torsten Pietsch, Ulrich Herrlinger, Christina Schaub

  • T lymphocyte recruitment to melanoma brain tumors depends on distinct venous vessels.

    Immunity

    Authors: Julia M Messmer, Calvin Thommek, Manuel Piechutta, Varun Venkataramani, Rebekka Wehner, Dana Westphal, Marc Schubert, Chanté D Mayer, Maike Effern, Anna S Berghoff, Daniel Hinze, Iris Helfrich, Dirk Schadendorf, Wolfgang Wick, Michael Hölzel, Matthia A Karreman, Frank Winkler

  • [What is confirmed in therapy of complicated urinary tract infections].

    Innere Medizin (Heidelberg, Germany)

    Authors: Sibylle von Vietinghoff, Florian Wagenlehner

  • Systemic dysregulation and molecular insights into poor influenza vaccine response in the aging population.

    Science advances

    Authors: Saumya Kumar, Martijn Zoodsma, Nhan Nguyen, Rodrigo Pedroso, Stephanie Trittel, Peggy Riese, Javier Botey-Bataller, Liang Zhou, Ahmed Alaswad, Haroon Arshad, Mihai G Netea, Cheng-Jian Xu, Frank Pessler, Carlos A Guzmán, Luis Graca, Yang Li

  • Insights into reproduction-regulating NOD-like receptors.

    Nature structural & molecular biology

    Authors: Inga V Hochheiser, Matthias Geyer

  • The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma.

    Scientific reports

    Authors: Michael Praktiknjo, Ana S Pena Solano, Farsaneh Sadeghlar, Thomas Welchowski, Matthias Schmid, Christian Möhring, Taotao Zhou, Robert Mahn, Malte B Monin, Carsten Meyer, Georg Feldmann, Peter Brossart, Cornelius van Beekum, Alexander Semaan, Hanno Matthaei, Steffen Manekeller, Alois M Sprinkart, Sebastian Nowak, Julian Luetkens, Jörg C Kalff, Christian P Strassburg, Maria A González-Carmona