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featured publications

  • The landscape of , and DNA methylation in head and neck squamous cell carcinomas.

    Epigenetics

    Authors: Luka de Vos, Ingela Grünwald, Emma Grace Bawden, Jörn Dietrich, Kathrin Scheckenbach, Constanze Wiek, Romina Zarbl, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich

  • (, ) DNA methylation correlates with LAG3 expression by tumor and immune cells, immune cell infiltration, and overall survival in clear cell renal cell carcinoma.

    Journal for immunotherapy of cancer

    Authors: Niklas Klümper, Damian J Ralser, Emma Grace Bawden, Jenny Landsberg, Romina Zarbl, Glen Kristiansen, Marieta Toma, Manuel Ritter, Michael Hölzel, Jörg Ellinger, Dimo Dietrich

  • Treatment of metastasized melanoma with combined checkpoint inhibition in a patient with highly active multiple sclerosis.

    The Journal of dermatology

    Authors: Friederike Hoffmann, Anne Fröhlich, Niklas Schäfer, Vera C Keil, Jennifer Landsberg, Ulrich Herrlinger, Judith Sirokay

  • Talimogene laherparepvec treatment to overcome loco-regional acquired resistance to immune checkpoint blockade in tumor stage IIIB-IV M1c melanoma patients.

    Cancer immunology, immunotherapy : CII

    Authors: Anne Fröhlich, Dennis Niebel, Simon Fietz, Eva Egger, Andrea Buchner, Judith Sirokay, Jennifer Landsberg

  • H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade.

    Clinical epigenetics

    Authors: Friederike Hoffmann, Dennis Niebel, Pia Aymans, Sandra Ferring-Schmitt, Dimo Dietrich, Jennifer Landsberg

  • Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma.

    EBioMedicine

    Authors: Anne Fröhlich, Sophia Loick, Emma Grace Bawden, Simon Fietz, Jörn Dietrich, Eric Diekmann, Gonzalo Saavedra, Holger Fröhlich, Dennis Niebel, Judith Sirokay, Romina Zarbl, Gerrit H Gielen, Glen Kristiansen, Friedrich Bootz, Jennifer Landsberg, Dimo Dietrich

  • Molecular and immune correlates of TIM-3 (HAVCR2) and galectin 9 (LGALS9) mRNA expression and DNA methylation in melanoma.

    Clinical epigenetics

    Authors: Tobias A W Holderried, Luka de Vos, Emma Grace Bawden, Timo J Vogt, Joern Dietrich, Romina Zarbl, Friedrich Bootz, Glen Kristiansen, Peter Brossart, Jennifer Landsberg, Dimo Dietrich

  • A matched-pair analysis on survival and response rates between German and non-German cancer patients treated at a Comprehensive Cancer Center.

    BMC cancer

    Authors: Marie K Budde, Walther Kuhn, Mignon-Denise Keyver-Paik, Friedrich Bootz, Jörg C Kalff, Stefan C Müller, Thomas Bieber, Peter Brossart, Hartmut Vatter, Ulrich Herrlinger, Dieter C Wirtz, Hans H Schild, Glen Kristiansen, Thorsten Pietsch, Stefan Aretz, Franziska Geiser, Lukas Radbruch, Rudolf H Reich, Christian P Strassburg, Dirk Skowasch, Markus Essler, Nicole Ernstmann, Jennifer Landsberg, Benjamin Funke, Ingo G H Schmidt-Wolf

  • DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients' survival, immune cell infiltrates, mutational load, and interferon γ signature.

    EBioMedicine

    Authors: Verena Sailer, Ulrike Sailer, Emma Grace Bawden, Romina Zarbl, Constanze Wiek, Timo J Vogt, Joern Dietrich, Sophia Loick, Ingela Grünwald, Marieta Toma, Carsten Golletz, Andreas Gerstner, Glen Kristiansen, Friedrich Bootz, Kathrin Scheckenbach, Jennifer Landsberg, Dimo Dietrich

  • Joint reconstruction and classification of tumor cells and cell interactions in melanoma tissue sections with synthesized training data.

    International journal of computer assisted radiology and surgery

    Authors: Alexander Effland, Erich Kobler, Anne Brandenburg, Teresa Klatzer, Leonie Neuhäuser, Michael Hölzel, Jennifer Landsberg, Thomas Pock, Martin Rumpf