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featured publications

  • Deep Learning to Predict the Future Growth of Geographic Atrophy from Fundus Autofluorescence.

    Ophthalmology science

    Authors: Anish Salvi, Julia Cluceru, Simon S Gao, Christina Rabe, Courtney Schiffman, Qi Yang, Aaron Y Lee, Pearse A Keane, Srinivas R Sadda, Frank G Holz, Daniela Ferrara, Neha Anegondi

  • A Quantitative Comparison Between Human and Artificial Intelligence in the Detection of Focal Cortical Dysplasia.

    Investigative radiology

    Authors: Lennart Walger, Tobias Bauer, David Kügler, Matthias H Schmitz, Fabiane Schuch, Christophe Arendt, Tobias Baumgartner, Johannes Birkenheier, Valeri Borger, Christoph Endler, Franziska Grau, Christian Immanuel, Markus Kölle, Patrick Kupczyk, Asadeh Lakghomi, Sarah Mackert, Elisabeth Neuhaus, Julia Nordsiek, Anna-Maria Odenthal, Karmele Olaciregui Dague, Laura Ostermann, Jan Pukropski, Attila Racz, Klaus von der Ropp, Frederic Carsten Schmeel, Felix Schrader, Aileen Sitter, Alexander Unruh-Pinheiro, Marilia Voigt, Martin Vychopen, Philip von Wedel, Randi von Wrede, Ulrike Attenberger, Hartmut Vatter, Alexandra Philipsen, Albert Becker, Martin Reuter, Elke Hattingen, Josemir W Sander, Alexander Radbruch, Rainer Surges, Theodor Rüber

  • Benchmarking methods for computing local sensitivities in ordinary differential equation models at dynamic and steady states.

    PloS one

    Authors: Polina Lakrisenko, Dilan Pathirana, Daniel Weindl, Jan Hasenauer

  • Genetic Prediction Modeling in Large Cohort Studies via Boosting Targeted Loss Functions.

    Statistics in medicine

    Authors: Hannah Klinkhammer, Christian Staerk, Carlo Maj, Peter M Krawitz, Andreas Mayr

  • ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA.

    Cell reports

    Authors: Ole Kristian Greiner-Tollersrud, Máté Krausz, Vincent Boehler, Aikaterini Polyzou, Maximilian Seidl, Ambra Spahiu, Zeinab Abdullah, Katarzyna Andryka-Cegielski, Felix Immunuel Dominick, Katrin Huebscher, Andreas Goschin, Cristian R Smulski, Eirini Trompouki, Regina Link, Hilmar Ebersbach, Honnappa Srinivas, Martine Marchant, Georgios Sogkas, Dieter Staab, Cathrine Vågbø, Danilo Guerini, Sebastian Baasch, Eicke Latz, Gunther Hartmann, Philippe Henneke, Roger Geiger, Xiao P Peng, Bodo Grimbacher, Eva Bartok, Ingrun Alseth, Max Warncke, Michele Proietti

  • Single-Cell Transcriptomics Unveils Skin Cell Specific Antifungal Immune Responses and IL-1Ra- IL-1R Immune Evasion Strategies of Emerging Fungal Pathogen .

    bioRxiv : the preprint server for biology

    Authors: Abishek Balakumar, Diprasom Das, Abhishek Datta, Abtar Mishra, Garrett Bryak, Shrihari M Ganesh, Mihai G Netea, Vinod Kumar, Michail S Lionakis, Devender Arora, Jyothi Thimmapuram, Shankar Thangamani

  • Differences of in vitro immune responses between patent and pre-patent Litomosoides sigmodontis-infected mice are independent of the filarial antigenic stimulus used.

    Parasitology research

    Authors: Kathrin Arndts, Anna Wiszniewsky, Anna-Lena Neumann, Katharina Wiszniewsky, Gnatoulma Katawa, Achim Hoerauf, Laura E Layland-Heni, Manuel Ritter, Marc P Hübner

  • Cauterization of the root of the left coronary artery as a straightforward, large and reproducible ischemic injury model in neonatal mice.

    Lab animal

    Authors: Tianyuan Hu, Bernd K Fleischmann, Mona Malek Mohammadi

  • Hepatocellular Cancer Surveillance in Patients with Advanced Chronic Liver Disease.

    NEJM evidence

    Authors: Wenyi Gu, Victor de Lédinghen, Christophe Aubé, Aleksander Krag, Christian Strassburg, Laurent Castéra, Jérôme Dumortier, Mireen Friedrich-Rust, Stanislas Pol, Ivica Grgurevic, Yasmin Zeleke, Michael Praktiknjo, Robert Schierwagen, Sabine Klein, Sven Francque, Halima Gottfriedová, Ioan Sporea, Philipp Schindler, Florian Rennebaum, Maximilian Joseph Brol, Martin Schulz, Frank Erhard Uschner, Julia Fischer, Cristina Margini, Wenping Wang, Adèle Delamarre, Jan Best, Ali Canbay, David Josef Maria Bauer, Benedikt Simbrunner, Georg Semmler, Thomas Reiberger, Jérôme Boursier, Ditlev Nytoft Rasmussen, Valérie Vilgrain, Aymeric Guibal, Stefan Zeuzem, Camille Vassord, Luisa Vonghia, Renata Šenkeříková, Alina Popescu, Annalisa Berzigotti, Wim Laleman, Maja Thiele, Christian Jansen, Jonel Trebicka

  • Deep Phenotyping of Pulmonary Edema and Pulmonary Vascular Permeability in COVID-19 ARDS.

    American journal of physiology. Lung cellular and molecular physiology

    Authors: Job R Schippers, Leila N Atmowihardjo, Erik Duijvelaar, Lars G Knaap, Mihai G Netea, Lilian J Meijboom, Lieuwe D J Bos, Harm Jan Bogaard, Jurjan Aman