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featured publications

  • BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue.

    The EMBO journal

    Authors: Katharina Sieckmann, Nora Winnerling, Dalila Juliana Silva Ribeiro, Seniz Yüksel, Ronja Kardinal, Lisa Maria Steinheuer, Fabian Frechen, Luis Henrique Corrêa, Geza Schermann, Christina Klausen, Nelli Blank-Stein, Jonas Schulte-Schrepping, Collins Osei-Sarpong, Matthias Becker, Lorenzo Bonaguro, Marc Beyer, Helen Louise May-Simera, Jelena Zurkovic, Christoph Thiele, Kevin Thurley, Lydia Sorokin, Carmen Ruiz de Almodovar, Elvira Mass, Dagmar Wachten

  • The long-term effect of metabolic bariatric surgery on innate immune cell phenotype and function.

    International journal of obesity (2005)

    Authors: Julia van Tuijl, Debby Vreeken, Wieteke Broeders, Benjamin Cossins, Liesbeth van Emst, Florine Seidel, Rinke Stienstra, Yang Li, Leo A B Joosten, Mihai G Netea, Eric J Hazebroek, Robert Kleemann, Amanda J Kiliaan, Siroon Bekkering, Niels P Riksen

  • Blood-based DNA methylation profiles in major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders.

    Comprehensive psychiatry

    Authors: Friederike S David, Josef Frank, Frederike Stein, Susanne Meinert, Lea Zillich, Lea Sirignano, Fabian Streit, Eva C Beins, Lisa Sindermann, Paula Usemann, Janik Goltermann, Elisabeth J Leehr, Sugirthan Sivalingam, Stefan Herms, Per Hoffmann, Tim Hahn, Stephanie H Witt, Nina Alexander, Tilo Kircher, Udo Dannlowski, Marcella Rietschel, Markus M Nöthen, Andreas J Forstner

  • Risk factors for dementia and cognitive impairment within 5 years after stroke: a prospective multicentre cohort study.

    The Lancet regional health. Europe

    Authors: Jule Filler, Marios K Georgakis, Daniel Janowitz, Marco Duering, Rong Fang, Anna Dewenter, Felix J Bode, Sebastian Stoesser, Christine Kindler, Peter Hermann, Christian H Nolte, Thomas G Liman, Lucia Kerti, Kathleen Bernkopf, Benno Ikenberg, Wenzel Glanz, Michael Wagner, Annika Spottke, Karin Waegemann, Michael Goertler, Silke Wunderlich, Matthias Endres, Inga Zerr, Gabor C Petzold, Martin Dichgans

  • Clinical outcomes of the PAUL glaucoma implant in primary open-angle and pseudoexfoliative glaucoma eyes after failed glaucoma surgeries.

    Acta ophthalmologica

    Authors: Constance Liegl, Leonie Bourauel, Benjamin Aretz, Diana Samarghitan, Wolfgang Walz, Michael Petrak, Frank G Holz, Raffael Liegl, Karl Mercieca

  • Image-based drug screening combined with molecular profiling identifies signatures and drivers of therapy resistance in pediatric AML.

    Cell reports. Medicine

    Authors: Ben Haladik, Margarita Maurer-Granofszky, Peter Zoescher, Raul Jimenez-Heredia, Alexandra Frohne, Anna Segarra-Roca, Chloe Casey, Felix Kartnig, Sarah Giuliani, Christina Rashkova, Peter Repiscak, Michael N Dworzak, Giulio Superti-Furga, Kaan Boztug

  • A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation.

    Molecular cell

    Authors: Jennifer R Devlin, Ben Martin, Nenad Bartonicek, Keziah Ting, Zheng Fan, Izabela Todorovski, Filip Bjelosevic, Sandra Verschoor, Annette Ciccone, Joseph A Trapani, Attila Horvath, Emily Tinsley, Peter Fraser, Andrea Newbold, Jarrod J Sandow, Andrea Muscat, Kaylene J Simpson, Matthias Geyer, Stephin J Vervoort, Ricky W Johnstone

  • A genome-wide association study identifies new loci associated with response to SARS-CoV-2 mRNA-1273 vaccine in a cohort of healthy healthcare workers.

    Frontiers in immunology

    Authors: Antonio José Cabrera-Serrano, Lucía Ruiz-Durán, Juan Francisco Gutiérrez-Bautista, María Carretero-Fernández, Rob Ter Horst, Yang Li, Fernando Jesús Reyes-Zurita, Francisco José García-Verdejo, Mihai G Netea, Pedro Sánchez-Rovira, Miguel Ángel López-Nevot, Antonio Sampedro, Juan Sainz

  • Plain language summary of publication of the 48-week results from the PULSAR study investigating how well a new dose of aflibercept works and how safe it is for people with wet age-related macular degeneration.

    Therapeutic advances in ophthalmology

    Authors: Paolo Lanzetta, Jean-François Korobelnik, Jeffrey S Heier, Sergio Leal, Frank G Holz, William Lloyd Clark, David Eichenbaum, Tomohiro Iida, Xiaodong Sun, Alyson J Berliner, Andrea Schulze, Thomas Schmelter, Ursula Schmidt-Ott, Xin Zhang, Robert Vitti, Karen W Chu, Kimberly Reed, Rohini Rao, Rafia Bhore, Yenchieh Cheng, Tien Y Wong

  • The expanding role of the NLRP3 inflammasome from periodic fevers to therapeutic targets.

    Nature immunology

    Authors: Alexander N R Weber, Róisín M McManus, Veit Hornung, Matthias Geyer, Jasmin B Kuemmerle-Deschner, Eicke Latz