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Publications

featured publications

  • Structural and immunogenic characterisation of ChAdOx1 Chik-derived Chikungunya VLPs supports a mechanistic rationale for vaccine-induced protection.

    Npj viruses

    Authors: Young Chan Kim, Xiyong Song, Yasunori Watanabe, Raquel de Oliveira Souza, Robert Stass, Sthefany Pagliari, Max Crispin, Beate Mareike Kümmerer, Carla Claser, Thomas A Bowden, Juha T Huiskonen, Arturo Reyes-Sandoval

  • Maturation-deficient chikungunya virus elicits protective immune responses in a murine challenge model.

    NPJ vaccines

    Authors: Danillo Lucas Alves Esposito, Jhefferson Barbosa Guimarães, Benedito Antonio Lopes da Fonseca, Beate Mareike Kümmerer

  • Use of Recombinant Chikungunya Virus expressing Nanoluciferase to Identify Chondrocytes as Target Cells in an Immunocompetent Mouse Model.

    The Journal of infectious diseases

    Authors: Vincent Legros, Essia Belarbi, Patricia Jeannin, Virginie Geolier, Beate M Kümmerer, David Hardy, Philippe Desprès, Antoine Gessain, Pierre Roques, Pierre-Emmanuel Ceccaldi, Valérie Choumet

  • RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I.

    The EMBO journal

    Authors: Alexander Kirchhoff, Anna-Maria Herzner, Christian Urban, Antonio Piras, Robert Düster, Julia Mahlberg, Agathe Grünewald, Thais M Schlee-Guimarães, Katrin Ciupka, Petro Leka, Robert J Bootz, Christina Wallerath, Charlotte Hunkler, Ann Kristin de Regt, Beate M Kümmerer, Maria Hønholt Christensen, Florian I Schmidt, Min Ae Lee-Kirsch, Claudia Günther, Hiroki Kato, Eva Bartok, Gunther Hartmann, Matthias Geyer, Andreas Pichlmair, Martin Schlee

  • Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein.

    NPJ vaccines

    Authors: Young Chan Kim, Yasunori Watanabe, Lücke Arlen-Celina, Xiyong Song, Raquel de Oliveira Souza, Robert Stass, Sasha R Azar, Shannan L Rossi, Carla Claser, Beate Mareike Kümmerer, Max Crispin, Thomas A Bowden, Juha T Huiskonen, Arturo Reyes-Sandoval

  • 2'-O-methyltransferase-deficient yellow fever virus: Restricted replication in the midgut and secondary tissues of Aedes aegypti mosquitoes severely limits dissemination.

    PLoS pathogens

    Authors: Anja Vom Hemdt, Alexandra L Thienel, Katrin Ciupka, Janett Wieseler, Hannah M Proksch, Martin Schlee, Beate M Kümmerer

  • Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture.

    Nature communications

    Authors: Vasiliya Kril, Michael Hons, Celine Amadori, Claire Zimberger, Laurine Couture, Yara Bouery, Julien Burlaud-Gaillard, Andrei Karpov, Denis Ptchelkine, Alexandra L Thienel, Beate M Kümmerer, Ambroise Desfosses, Rhian Jones, Philippe Roingeard, Laurent Meertens, Ali Amara, Juan Reguera

  • Viral hijacking of hnRNPH1 unveils a G-quadruplex-driven mechanism of stress control.

    Cell host & microbe

    Authors: Philipp Schult, Beate Mareike Kümmerer, Markus Hafner, Katrin Paeschke

  • TMPRSS2 isoform 1 downregulation by G-quadruplex stabilization induces SARS-CoV-2 replication arrest.

    BMC biology

    Authors: Alessio De Magis, Philipp Schult, Antonia Schönleber, Rebecca Linke, Kerstin U Ludwig, Beate M Kümmerer, Katrin Paeschke

  • Top publication

    Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury.

    Journal of hepatology

    Authors: Carl-Philipp Hackstein, Jasper Spitzer, Konstantinos Symeonidis, Helena Horvatic, Tanja Bedke, Babett Steglich, Sabine Klein, Lisa M Assmus, Alexandru Odainic, Jennifer Szlapa, Nina Kessler, Marc Beyer, Ricarda Schmithausen, Eicke Latz, Richard A Flavell, Natalio Garbi, Christian Kurts, Beate M Kümmerer, Jonel Trebicka, Axel Roers, Samuel Huber, Susanne V Schmidt, Percy A Knolle, Zeinab Abdullah