An antibiotic from an uncultured bacterium binds to an immutable target.
Cell
Authors:
Rhythm Shukla, Aaron J Peoples, Kevin C Ludwig, Sourav Maity, Maik G N Derks, Stefania De Benedetti, Annika M Krueger, Bram J A Vermeulen, Theresa Harbig, Francesca Lavore, Raj Kumar, Rodrigo V Honorato, Fabian Grein, Kay Nieselt, Yangping Liu, Alexandre M J J Bonvin, Marc Baldus, Ulrich Kubitscheck, Eefjan Breukink, Catherine Achorn, Anthony Nitti, Christopher J Schwalen, Amy L Spoering, Losee Lucy Ling, Dallas Hughes, Moreno Lelli, Wouter H Roos, Kim Lewis, Tanja Schneider, Markus Weingarth
Dual targeting of the class V lanthipeptide antibiotic cacaoidin.
iScience
Authors:
Julia P Deisinger, Melina Arts, Ioli Kotsogianni, Jan-Samuel Puls, Fabian Grein, Francisco Javier Ortiz-López, Nathaniel I Martin, Anna Müller, Olga Genilloud, Tanja Schneider