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Featured publications

  • Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action.

    The ISME journal

    Authors: Jan-Samuel Puls, Benjamin Winnerling, Jeffrey John Power, Annika Marie Krüger, Dominik Brajtenbach, Matthew Johnson, Kevser Bilici, Laura Camus, Thomas Fließwasser, Tanja Schneider, Hans-Georg Sahl, Debnath Ghosal, Ulrich Kubitscheck, Simon Heilbronner, Fabian Grein

  • An antibiotic from an uncultured bacterium binds to an immutable target.

    Cell

    Authors: Rhythm Shukla, Aaron J Peoples, Kevin C Ludwig, Sourav Maity, Maik G N Derks, Stefania De Benedetti, Annika M Krueger, Bram J A Vermeulen, Theresa Harbig, Francesca Lavore, Raj Kumar, Rodrigo V Honorato, Fabian Grein, Kay Nieselt, Yangping Liu, Alexandre M J J Bonvin, Marc Baldus, Ulrich Kubitscheck, Eefjan Breukink, Catherine Achorn, Anthony Nitti, Christopher J Schwalen, Amy L Spoering, Losee Lucy Ling, Dallas Hughes, Moreno Lelli, Wouter H Roos, Kim Lewis, Tanja Schneider, Markus Weingarth

  • Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division.

    Science advances

    Authors: Jan-Samuel Puls, Dominik Brajtenbach, Tanja Schneider, Ulrich Kubitscheck, Fabian Grein

  • Dual targeting of the class V lanthipeptide antibiotic cacaoidin.

    iScience

    Authors: Julia P Deisinger, Melina Arts, Ioli Kotsogianni, Jan-Samuel Puls, Fabian Grein, Francisco Javier Ortiz-López, Nathaniel I Martin, Anna Müller, Olga Genilloud, Tanja Schneider

  • Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations.

    eLife

    Authors: Ashelyn E Sidders, Katarzyna M Kedziora, Melina Arts, Jan-Martin Daniel, Stefania de Benedetti, Jenna E Beam, Duyen T Bui, Joshua B Parsons, Tanja Schneider, Sarah E Rowe, Brian P Conlon

  • An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis.

    PLoS pathogens

    Authors: Jula Reuter, Christian Otten, Nicolas Jacquier, Junghoon Lee, Dominique Mengin-Lecreulx, Iris Löckener, Robert Kluj, Christoph Mayer, Federico Corona, Julia Dannenberg, Sébastien Aeby, Henrike Bühl, Gilbert Greub, Waldemar Vollmer, Scot P Ouellette, Tanja Schneider, Beate Henrichfreise

  • Modular Synthesis of Halogenated Xanthones by a Divergent Coupling Strategy.

    The Journal of organic chemistry

    Authors: Jonas W Meringdal, Alexander Kilian, Wingkee C Li, Maximilian J B Heinemann, Marvin Rausch, Tanja Schneider, Dirk Menche

  • Crystal structure of the lipid flippase MurJ in a "squeezed" form distinct from its inward- and outward-facing forms.

    Structure (London, England : 1993)

    Authors: Hidetaka Kohga, Takaharu Mori, Yoshiki Tanaka, Kunihito Yoshikaie, Katsuhide Taniguchi, Kei Fujimoto, Lisa Fritz, Tanja Schneider, Tomoya Tsukazaki

  • Versatile synthesis of pathogen specific bacterial cell wall building blocks.

    RSC advances

    Authors: Lukas Martin Wingen, Christina Braun, Marvin Rausch, Harald Gross, Tanja Schneider, Dirk Menche

  • Visualizing the mode of action and supramolecular assembly of teixobactin analogues in .

    Chemical science

    Authors: Michael A Morris, Alexander Vallmitjana, Fabian Grein, Tanja Schneider, Melina Arts, Chelsea R Jones, Betty T Nguyen, Mohammad H Hashemian, Melody Malek, Enrico Gratton, James S Nowick