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Publications

featured publications

  • Sophisticated natural products as antibiotics.

    Nature

    Authors: Kim Lewis, Richard E Lee, Heike Brötz-Oesterhelt, Sebastian Hiller, Marina V Rodnina, Tanja Schneider, Markus Weingarth, Ingo Wohlgemuth

  • A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens.

    Proceedings of the National Academy of Sciences of the United States of America

    Authors: Ned P Buijs, Halana C Vlaming, Ioli Kotsogianni, Melina Arts, Joost Willemse, Yunhao Duan, Francesca M Alexander, Stephen A Cochrane, Tanja Schneider, Nathaniel I Martin

  • Synthesis of Bisindole Alkaloids and Their Mode of Action against Methicillin-Resistant .

    ACS infectious diseases

    Authors: Emmanuel T Adeniyi, Marco Kruppa, Stefania De Benedetti, Kevin C Ludwig, Violetta Krisilia, Tobias R Wassenberg, Melissa Both, Tanja Schneider, Thomas J J Müller, Rainer Kalscheuer

  • The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular and and Break the Persistence Phenotype in .

    Antibiotics (Basel, Switzerland)

    Authors: Iris Löckener, Lara Vanessa Behrmann, Jula Reuter, Andrea Schiefer, Anna Klöckner, Sebastian Krannich, Christian Otten, Katja Mölleken, Satoshi Ichikawa, Achim Hoerauf, Tanja Schneider, Kenneth M Pfarr, Beate Henrichfreise

  • Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action.

    The ISME journal

    Authors: Jan-Samuel Puls, Benjamin Winnerling, Jeffrey John Power, Annika Marie Krüger, Dominik Brajtenbach, Matthew Johnson, Kevser Bilici, Laura Camus, Thomas Fließwasser, Tanja Schneider, Hans-Georg Sahl, Debnath Ghosal, Ulrich Kubitscheck, Simon Heilbronner, Fabian Grein

  • An antibiotic from an uncultured bacterium binds to an immutable target.

    Cell

    Authors: Rhythm Shukla, Aaron J Peoples, Kevin C Ludwig, Sourav Maity, Maik G N Derks, Stefania De Benedetti, Annika M Krueger, Bram J A Vermeulen, Theresa Harbig, Francesca Lavore, Raj Kumar, Rodrigo V Honorato, Fabian Grein, Kay Nieselt, Yangping Liu, Alexandre M J J Bonvin, Marc Baldus, Ulrich Kubitscheck, Eefjan Breukink, Catherine Achorn, Anthony Nitti, Christopher J Schwalen, Amy L Spoering, Losee Lucy Ling, Dallas Hughes, Moreno Lelli, Wouter H Roos, Kim Lewis, Tanja Schneider, Markus Weingarth

  • Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division.

    Science advances

    Authors: Jan-Samuel Puls, Dominik Brajtenbach, Tanja Schneider, Ulrich Kubitscheck, Fabian Grein

  • Dual targeting of the class V lanthipeptide antibiotic cacaoidin.

    iScience

    Authors: Julia P Deisinger, Melina Arts, Ioli Kotsogianni, Jan-Samuel Puls, Fabian Grein, Francisco Javier Ortiz-López, Nathaniel I Martin, Anna Müller, Olga Genilloud, Tanja Schneider

  • Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations.

    eLife

    Authors: Ashelyn E Sidders, Katarzyna M Kedziora, Melina Arts, Jan-Martin Daniel, Stefania de Benedetti, Jenna E Beam, Duyen T Bui, Joshua B Parsons, Tanja Schneider, Sarah E Rowe, Brian P Conlon

  • An NlpC/P60 protein catalyzes a key step in peptidoglycan recycling at the intersection of energy recovery, cell division and immune evasion in the intracellular pathogen Chlamydia trachomatis.

    PLoS pathogens

    Authors: Jula Reuter, Christian Otten, Nicolas Jacquier, Junghoon Lee, Dominique Mengin-Lecreulx, Iris Löckener, Robert Kluj, Christoph Mayer, Federico Corona, Julia Dannenberg, Sébastien Aeby, Henrike Bühl, Gilbert Greub, Waldemar Vollmer, Scot P Ouellette, Tanja Schneider, Beate Henrichfreise