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Publications

featured publications

  • Closing the gap between formats for storing layout information in systems biology.

    Briefings in bioinformatics

    Authors: David Hoksza, Piotr Gawron, Marek Ostaszewski, Jan Hasenauer, Reinhard Schneider

  • Efficient exact inference for dynamical systems with noisy measurements using sequential approximate Bayesian computation.

    Bioinformatics (Oxford, England)

    Authors: Yannik Schälte, Jan Hasenauer

  • COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms.

    Scientific data

    Authors: Marek Ostaszewski, Alexander Mazein, Marc E Gillespie, Inna Kuperstein, Anna Niarakis, Henning Hermjakob, Alexander R Pico, Egon L Willighagen, Chris T Evelo, Jan Hasenauer, Falk Schreiber, Andreas Dräger, Emek Demir, Olaf Wolkenhauer, Laura I Furlong, Emmanuel Barillot, Joaquin Dopazo, Aurelio Orta-Resendiz, Francesco Messina, Alfonso Valencia, Akira Funahashi, Hiroaki Kitano, Charles Auffray, Rudi Balling, Reinhard Schneider

  • Model-based analysis of response and resistance factors of cetuximab treatment in gastric cancer cell lines.

    PLoS computational biology

    Authors: Elba Raimúndez, Simone Keller, Gwen Zwingenberger, Karolin Ebert, Sabine Hug, Fabian J Theis, Dieter Maier, Birgit Luber, Jan Hasenauer

  • Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes.

    Cell reports

    Authors: Constance Alabert, Carolin Loos, Moritz Voelker-Albert, Simona Graziano, Ignasi Forné, Nazaret Reveron-Gomez, Lea Schuh, Jan Hasenauer, Carsten Marr, Axel Imhof, Anja Groth

  • Efficient parameterization of large-scale dynamic models based on relative measurements.

    Bioinformatics (Oxford, England)

    Authors: Leonard Schmiester, Yannik Schälte, Fabian Fröhlich, Jan Hasenauer, Daniel Weindl

  • Robust calibration of hierarchical population models for heterogeneous cell populations.

    Journal of theoretical biology

    Authors: Carolin Loos, Jan Hasenauer

  • Inference of finite mixture models and the effect of binning.

    Statistical applications in genetics and molecular biology

    Authors: Eva-Maria Geissen, Jan Hasenauer, Nicole E Radde

  • Erratum: Publisher Correction: Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection.

    NPJ systems biology and applications

    Authors: Fabian Fröhlich, Anita Reiser, Laura Fink, Daniel Woschée, Thomas Ligon, Fabian Joachim Theis, Joachim Oskar Rädler, Jan Hasenauer

  • Comparison of null models for combination drug therapy reveals Hand model as biochemically most plausible.

    Scientific reports

    Authors: Mark Sinzger, Jakob Vanhoefer, Carolin Loos, Jan Hasenauer