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featured publications

  • Intermediate monocytes are associated with the first major adverse cardiovascular event in patients with stable coronary artery disease.

    International journal of cardiology

    Authors: Mihaela I Dregoesc, Adrian B Țigu, Siroon Bekkering, Charlotte D C C van der Heijden, Laura Rodwell, Sorana D Bolboacă, Leo A B Joosten, Mihai G Netea, Niels P Riksen, Adrian C Iancu

  • Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.

    Immunity

    Authors: Simone J C F M Moorlag, Lukas Folkman, Rob Ter Horst, Thomas Krausgruber, Daniele Barreca, Linda C Schuster, Victoria Fife, Vasiliki Matzaraki, Wenchao Li, Stephan Reichl, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Helga Dijkstra, Heidi Lemmers, Bram van Cranenbroek, Esther van Rijssen, Hans J P M Koenen, Irma Joosten, Cheng-Jian Xu, Yang Li, Leo A B Joosten, Reinout van Crevel, Mihai G Netea, Christoph Bock

  • Host genetic regulation of human gut microbial structural variation.

    Nature

    Authors: Daria V Zhernakova, Daoming Wang, Lei Liu, Sergio Andreu-Sánchez, Yue Zhang, Angel J Ruiz-Moreno, Haoran Peng, Niels Plomp, Ángela Del Castillo-Izquierdo, Ranko Gacesa, Esteban A Lopera-Maya, Godfrey S Temba, Vesla I Kullaya, Sander S van Leeuwen, Ramnik J Xavier, Quirijn de Mast, Leo A B Joosten, Niels P Riksen, Joost H W Rutten, Mihai G Netea, Serena Sanna, Cisca Wijmenga, Rinse K Weersma, Alexandra Zhernakova, Hermie J M Harmsen, Jingyuan Fu

  • The pathophysiology of sepsis and precision-medicine-based immunotherapy.

    Nature immunology

    Authors: Evangelos J Giamarellos-Bourboulis, Anna C Aschenbrenner, Michael Bauer, Christoph Bock, Thierry Calandra, Irit Gat-Viks, Evdoxia Kyriazopoulou, Mihaela Lupse, Guillaume Monneret, Peter Pickkers, Joachim L Schultze, Tom van der Poll, Frank L van de Veerdonk, Alexander P J Vlaar, Sebastian Weis, W Joost Wiersinga, Mihai G Netea

  • Top publication

    BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination.

    Nature communications

    Authors: Krista E van Meijgaarden, Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Hans J P M Koenen, Leo A B Joosten, Annapurna Vyakarnam, Asma Ahmed, Srabanti Rakshit, Vasista Adiga, Tom H M Ottenhoff, Yang Li, Mihai G Netea, Simone A Joosten

  • Survival of Environment-Derived Opportunistic Bacterial Pathogens to Martian Conditions: Is There a Concern for Human Missions to Mars?

    Astrobiology

    Authors: Tommaso Zaccaria, Marien I de Jonge, Jorge Domínguez-Andrés, Mihai G Netea, Kristina Beblo-Vranesevic, Petra Rettberg

  • Sex-specific association of visceral and subcutaneous adipose tissue volumes with systemic inflammation and innate immune cells in people living with obesity.

    International journal of obesity (2005)

    Authors: Inge C L van den Munckhof, Harsh Bahrar, Kiki Schraa, Tessa Brand, Rob Ter Horst, Marinette van der Graaf, Helena M Dekker, Rinke Stienstra, Jacqueline de Graaf, Leo A B Joosten, Mihai G Netea, Niels P Riksen, Joost H W Rutten

  • Enduring echoes: Post-infectious long-term changes in innate immunity.

    European journal of internal medicine

    Authors: Elisabeth A Dulfer, Leo A B Joosten, Mihai G Netea

  • No Association Between BCG Instillations and COVID-19 Incidence in a Dutch Non-Muscle Invasive Bladder Cancer Cohort.

    Bladder cancer (Amsterdam, Netherlands)

    Authors: Moniek van Zutphen, Lambertus A L M Kiemeney, Ursula T H Oldenhof, Jake S F Maurits, J Alfred Witjes, Leo A B Joosten, Mihai G Netea, Katja K H Aben, Alina Vrieling, Sita H Vermeulen

  • Stratification of Atherosclerosis based on Plasma Metabolic States.

    The Journal of clinical endocrinology and metabolism

    Authors: Yuval Menaker, Inge van den Munckhof, Alice Scarpa, Katarzyna Placek, Rachel Brandes-Leibovitz, Yossef Glantzspiegel, Leo A B Joosten, Joost H W Rutten, Mihai G Netea, Irit Gat-Viks, Niels P Riksen