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featured publications

  • CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma.

    Clinical epigenetics

    Authors: Friederike Hoffmann, Alina Franzen, Luka de Vos, Lennert Wuest, Zsófi Kulcsár, Simon Fietz, Alexander Philippe Maas, Sarah Hollick, Marie Yatou Diop, Jennis Gabrielpillai, Timo Vogt, Pia Kuster, Romina Zarbl, Joern Dietrich, Glen Kristiansen, Peter Brossart, Jennifer Landsberg, Sebastian Strieth, Dimo Dietrich

  • Routine vaccination for influenza and pneumococcal disease and its effect on COVID-19 in a population of Dutch older adults.

    Vaccine: X

    Authors: Esther J M Taks, Konstantin Föhse, Simone J C F M Moorlag, Jacobien Hoogerwerf, Reinout van Crevel, Cornelis H van Werkhoven, Mihai G Netea, Jaap Ten Oever

  • Transcatheter edge-to-edge valve repair versus minimally invasive beating-heart surgery of the tricuspid valve: an observational study.

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    Authors: Nihal Wilde, Miriam Silaschi, Hossien Alirezaei, Johanna Vogelhuber, Atsushi Sugiura, Tetsu Tanaka, Mitsumasa Sudo, Refik Kavsur, Franca Cattelaens, Ali El-Sayed Ahmad, Mirko Doss, Wolfgang Fehske, Sebastian Zimmer, Georg Nickenig, Farhad Bakhtiary, Marcel Weber

  • ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux.

    The Journal of cell biology

    Authors: Fátima Martín-Sánchez, Vincent Compan, Alejandro Peñín-Franch, Ana Tapia-Abellán, Ana I Gómez, María C Baños-Gregori, Florian I Schmidt, Pablo Pelegrin

  • Rifaximin may induce rifampicin resistance in coagulase-negative staphylococci.

    Liver international : official journal of the International Association for the Study of the Liver

    Authors: Lina M Schulte, Jacob Nattermann, Christian P Strassburg, Philipp Lutz

  • Test-Retest Variability and Discriminatory Power of Measurements From Microperimetry and Dark Adaptation Assessment in People With Intermediate Age-Related Macular Degeneration - A MACUSTAR Study Report.

    Translational vision science & technology

    Authors: Bethany E Higgins, Giovanni Montesano, Hannah M P Dunbar, Alison M Binns, Deanna J Taylor, Charlotte Behning, Amina Abdirahman, Matthias C Schmid, Jan H Terheyden, Nadia Zakaria, Stephen Poor, Robert P Finger, Sergio Leal, Frank G Holz, Gary S Rubin, Ulrich F O Luhmann, David P Crabb

  • Relative Ellipsoid Zone Reflectivity in Macular Telangiectasia Type 2.

    Investigative ophthalmology & visual science

    Authors: Lukas Goerdt, Leonie Weinhold, Ben Isselmann, Jose Luis Rodriguez Garcia, Sandrine H Künzel, Matthias Schmid, Frank G Holz, Simone Tzaridis, Sarah Thiele

  • Stimulation of Immune Checkpoint Molecule B and T-Lymphocyte Attenuator Alleviates Experimental Crescentic Glomerulonephritis.

    Journal of the American Society of Nephrology : JASN

    Authors: Paul Diefenhardt, Marie Braumann, Thomas Schömig, Bastian Trinsch, Claudio Sierra Gonzalez, Janine Becker-Gotot, Linus A Völker, Lioba Ester, Amrei M Mandel, Daniel Hawiger, Ali T Abdallah, Bernhard Schermer, Heike Göbel, Paul Brinkkötter, Christian Kurts, Thomas Benzing, Sebastian Brähler

  • AI-based multi-PRS models outperform classical single-PRS models.

    Frontiers in genetics

    Authors: Jan Henric Klau, Carlo Maj, Hannah Klinkhammer, Peter M Krawitz, Andreas Mayr, Axel M Hillmer, Johannes Schumacher, Dominik Heider

  • Adenylation Domain-Guided Recruitment of Acting Nonheme Monooxygenases in Nonribosomal Peptide Biosynthesis.

    ACS chemical biology

    Authors: Daniel A Wirtz, Niels Schneberger, Sophie Klöppel, René Richarz, Matthias Geyer, Gabriele M König, Gregor Hagelueken, Max Crüsemann