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  • Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline.

    Alzheimer's & dementia (Amsterdam, Netherlands)

    Authors: Stefan J Teipel, Martin Dyrba, Luca Kleineidam, Frederic Brosseron, Fedor Levin, Davide Bruno, Katharina Buerger, Nicoleta Cosma, Luisa-Sophie Schneider, Emrah Düzel, Wenzel Glanz, Klaus Fliessbach, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Matthias H Munk, Franziska Maier, Oliver Peters, Nunzio Pomara, Robert Perneczky, Boris-Stephan Rauchmann, Josef Priller, Alfredo Ramirez, Nina Roy, Anja Schneider, Annika Spottke, Eike J Spruth, Sandra Roeske, Michael Wagner, Jens Wiltfang, Steffen Wolfsgruber, Claudia Bartels, Frank Jessen, Michael T Heneka

  • Efficacy and safety of fexinidazole for treatment of chronic indeterminate Chagas disease (FEXI-12): a multicentre, randomised, double-blind, phase 2 trial.

    The Lancet. Infectious diseases

    Authors: Maria-Jesus Pinazo, Colin Forsyth, Irene Losada, Elena Trigo Esteban, Magdalena García-Rodríguez, Maria Luz Villegas, Israel Molina, Clara Crespillo-Andújar, Montserrat Gállego, Cristina Ballart, Juan Carlos Ramirez, Tilman Aden, Achim Hoerauf, Kenneth Pfarr, Michel Vaillant, Tayná Marques, Jayme Fernandes, Bethania Blum, Isabela Ribeiro, Sergio Sosa-Estani, Fabiana Barreira, Joaquim Gascón

  • Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.

    Immunity

    Authors: Simone J C F M Moorlag, Lukas Folkman, Rob Ter Horst, Thomas Krausgruber, Daniele Barreca, Linda C Schuster, Victoria Fife, Vasiliki Matzaraki, Wenchao Li, Stephan Reichl, Vera P Mourits, Valerie A C M Koeken, L Charlotte J de Bree, Helga Dijkstra, Heidi Lemmers, Bram van Cranenbroek, Esther van Rijssen, Hans J P M Koenen, Irma Joosten, Cheng-Jian Xu, Yang Li, Leo A B Joosten, Reinout van Crevel, Mihai G Netea, Christoph Bock

  • Associations of TACSTD2/TROP2 and NECTIN-4/NECTIN-4 with molecular subtypes, PD-L1 expression, and FGFR3 mutational status in two advanced urothelial bladder cancer cohorts.

    Histopathology

    Authors: Veronika Bahlinger, Annalena Branz, Pamela L Strissel, Reiner Strick, Fabienne Lange, Carol I Geppert, Niklas Klümper, Michael Hölzel, Sven Wach, Helge Taubert, Danijel Sikic, Bernd Wullich, Miriam Angeloni, Fulvia Ferrazzi, Lauri Diehl, Maria Kovalenko, Emon Elboudwarej, Juliane M Jürgensmeier, Arndt Hartmann, Markus Eckstein

  • Inflammasomes in neurological disorders - mechanisms and therapeutic potential.

    Nature reviews. Neurology

    Authors: Kishore Aravind Ravichandran, Michael T Heneka

  • EPAC1 enhances brown fat growth and beige adipogenesis.

    Nature cell biology

    Authors: Laia Reverte-Salisa, Sana Siddig, Staffan Hildebrand, Xi Yao, Jelena Zurkovic, Michelle Y Jaeckstein, Joerg Heeren, Frank Lezoualc'h, Natalie Krahmer, Alexander Pfeifer

  • CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates lipogenesis in adipose tissue.

    Frontiers in immunology

    Authors: Michelle Y Jaeckstein, Isabell Schulze, Michael Wolfgang Zajac, Markus Heine, Oliver Mann, Alexander Pfeifer, Joerg Heeren

  • Efficacy and Safety of Methotrexate in Psoriasis Vulgaris Long-Term Treatment: A Real-World Observation Study.

    Indian journal of dermatology

    Authors: Dagmar Wilsmann-Theis, Rhena Funk, Rotraut Mössner, Thomas Bieber, Jörg Wenzel

  • Multicentric assessment of safety and efficacy of combinatorial adjuvant brain metastasis treatment by intraoperative radiotherapy and immunotherapy.

    International journal of radiation oncology, biology, physics

    Authors: Julian P Layer, Ehab Shiban, Stefanie Brehmer, Christian D Diehl, Douglas Guedes de Castro, Motaz Hamed, Cas S Dejonckheere, Daniel T Cifarelli, Lea L Friker, Ulrich Herrlinger, Michael Hölzel, Hartmut Vatter, Matthias Schneider, Stephanie E Combs, Leonard Christopher Schmeel, Christopher P Cifarelli, Frank A Giordano, Gustavo R Sarria, Klaus-Henning Kahl

  • DNA damage signaling in macrophages modulates systemic cytokine levels in response to oxidative stress.

    eLife

    Authors: Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf