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Publications

featured publications

  • Single-cell RNA sequencing reveals induction of distinct trained-immunity programs in human monocytes.

    The Journal of clinical investigation

    Authors: Bowen Zhang, Simone Jcfm Moorlag, Jorge Dominguez-Andres, Özlem Bulut, Gizem Kilic, Zhaoli Liu, Reinout van Crevel, Cheng-Jian Xu, Leo Ab Joosten, Mihai G Netea, Yang Li

  • Evolutionary Trajectories of Complex Traits in European Populations of Modern Humans.

    Frontiers in genetics

    Authors: Yunus Kuijpers, Jorge Domínguez-Andrés, Olivier B Bakker, Manoj Kumar Gupta, Martin Grasshoff, Cheng-Jian Xu, Leo A B Joosten, Jaume Bertranpetit, Mihai G Netea, Yang Li

  • The gut microbiome as mediator between diet and its impact on immune function.

    Scientific reports

    Authors: Huiqing Shi, Rob Ter Horst, Suzanne Nielen, Mirjam Bloemendaal, Martin Jaeger, Irma Joosten, Hans Koenen, Leo A B Joosten, Lizanne J S Schweren, Alejandro Arias Vasquez, Mihai G Netea, Jan Buitelaar

  • Borrelia burgdorferi inhibits NADPH-mediated reactive oxygen species production through the mTOR pathway.

    Ticks and tick-borne diseases

    Authors: Mariska Kerstholt, Michelle Brouwer, Marcel Te Vrugt, Marije Oosting, Mihai G Netea, Leo A B Joosten

  • Development and validation of SCOPE score: A clinical score to predict COVID-19 pneumonia progression to severe respiratory failure.

    Cell reports. Medicine

    Authors: Evangelos J Giamarellos-Bourboulis, Garyfallia Poulakou, Aline de Nooijer, Haralampos Milionis, Simeon Metallidis, Michalis Ploumidis, Pinelopi Grigoropoulou, Aggeliki Rapti, Francesco Vladimiro Segala, Evangelos Balis, Efthymia Giannitsioti, Paola Rodari, Ilias Kainis, Zoi Alexiou, Emanuele Focà, Brollo Lucio, Nikoletta Rovina, Laura Scorzolini, Maria Dafni, Sofia Ioannou, Alessandro Tomelleri, Katerina Dimakou, Glykeria Tzatzagou, Maria Chini, Matteo Bassetti, Christina Trakatelli, George Tsoukalas, Carlo Selmi, Charilaos Samaras, Maria Saridaki, Athina Pyrpasopoulou, Elisabeth Kaldara, Ilias Papanikolaou, Aikaterini Argyraki, Karolina Akinosoglou, Marina Koupetori, Periklis Panagopoulos, George N Dalekos, Mihai G Netea

  • BCG vaccination provides protection against IAV but not SARS-CoV-2.

    Cell reports

    Authors: Eva Kaufmann, Nargis Khan, Kim A Tran, Antigona Ulndreaj, Erwan Pernet, Ghislaine Fontes, Andréanne Lupien, Patrice Desmeules, Fiona McIntosh, Amina Abow, Simone J C F M Moorlag, Priya Debisarun, Karen Mossman, Arinjay Banerjee, Danielle Karo-Atar, Mina Sadeghi, Samira Mubareka, Donald C Vinh, Irah L King, Clinton S Robbins, Marcel A Behr, Mihai G Netea, Philippe Joubert, Maziar Divangahi

  • BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial.

    NPJ vaccines

    Authors: Joshua Gillard, Bastiaan A Blok, Daniel R Garza, Prashanna Balaji Venkatasubramanian, Elles Simonetti, Marc J Eleveld, Guy A M Berbers, Pieter G M van Gageldonk, Irma Joosten, Ronald de Groot, L Charlotte J de Bree, Reinout van Crevel, Marien I de Jonge, Martijn A Huynen, Mihai G Netea, Dimitri A Diavatopoulos

  • A functional genomics approach in Tanzanian population identifies distinct genetic regulators of cytokine production compared to European population.

    American journal of human genetics

    Authors: Collins K Boahen, Godfrey S Temba, Vesla I Kullaya, Vasiliki Matzaraki, Leo A B Joosten, Gibson Kibiki, Blandina T Mmbaga, Andre van der Ven, Quirijn de Mast, Mihai G Netea, Vinod Kumar

  • Differences in thrombin and plasmin generation potential between East African and Western European adults: The role of genetic and non-genetic factors.

    Journal of thrombosis and haemostasis : JTH

    Authors: Godfrey S Temba, Nadira Vadaq, Jun Wan, Vesla Kullaya, Dana Huskens, Tal Pecht, Martin Jaeger, Collins K Boahen, Vasiliki Matzaraki, Wieteke Broeders, Leo A B Joosten, Sultana M H Faradz, Gibson Kibiki, Saskia Middeldorp, Duccio Cavalieri, Paolo Lionetti, Philip G de Groot, Joachim L Schultze, Mihai G Netea, Vinod Kumar, Bas de Laat, Blandina T Mmbaga, Andre J van der Ven, Mark Roest, Quirijn de Mast

  • Relation Between Plasma Proteomics Analysis and Major Adverse Cardiovascular Events in Patients With Stable Coronary Artery Disease.

    Frontiers in cardiovascular medicine

    Authors: Mihaela Ioana Dregoesc, Adrian Bogdan Ţigu, Siroon Bekkering, Charlotte D C C van der Heijden, Sorana Daniela Bolboacǎ, Leo A B Joosten, Frank L J Visseren, Mihai G Netea, Niels P Riksen, Adrian Corneliu Iancu