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featured publications

  • Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis.

    Circulation

    Authors: Laurienne Edgar, Naveed Akbar, Adam T Braithwaite, Thomas Krausgruber, Héctor Gallart-Ayala, Jade Bailey, Alastair L Corbin, Tariq E Khoyratty, Joshua T Chai, Mohammad Alkhalil, André F Rendeiro, Klemen Ziberna, Ritu Arya, Thomas J Cahill, Christoph Bock, Jurga Laurencikiene, Mark J Crabtree, Madeleine E Lemieux, Niels P Riksen, Mihai G Netea, Craig E Wheelock, Keith M Channon, Mikael Rydén, Irina A Udalova, Ricardo Carnicer, Robin P Choudhury

  • Lung Epithelial Signaling Mediates Early Vaccine-Induced CD4 T Cell Activation and Control.

    mBio

    Authors: Shibali Das, Nancy D Marin, Ekaterina Esaulova, Mushtaq Ahmed, Amanda Swain, Bruce A Rosa, Makedonka Mitreva, Javier Rangel-Moreno, Mihai G Netea, Luis B Barreiro, Maziar Divangahi, Maxim N Artyomov, Deepak Kaushal, Shabaana A Khader

  • Human Newborn Monocytes Demonstrate Distinct BCG-Induced Primary and Trained Innate Cytokine Production and Metabolic Activation .

    Frontiers in immunology

    Authors: Asimenia Angelidou, Joann Diray-Arce, Maria-Giulia Conti, Mihai G Netea, Bastiaan A Blok, Mark Liu, Guzman Sanchez-Schmitz, Al Ozonoff, Simon D van Haren, Ofer Levy

  • Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.

    Genome biology

    Authors: Xiaojing Chu, Martin Jaeger, Joep Beumer, Olivier B Bakker, Raul Aguirre-Gamboa, Marije Oosting, Sanne P Smeekens, Simone Moorlag, Vera P Mourits, Valerie A C M Koeken, Charlotte de Bree, Trees Jansen, Ian T Mathews, Khoi Dao, Mahan Najhawan, Jeramie D Watrous, Irma Joosten, Sonia Sharma, Hans J P M Koenen, Sebo Withoff, Iris H Jonkers, Romana T Netea-Maier, Ramnik J Xavier, Lude Franke, Cheng-Jian Xu, Leo A B Joosten, Serena Sanna, Mohit Jain, Vinod Kumar, Hans Clevers, Cisca Wijmenga, Mihai G Netea, Yang Li

  • Assessing the effect of BCG revaccination on long-term mortality.

    The Lancet. Infectious diseases

    Authors: Mihai G Netea, Reinout van Crevel

  • Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis.

    Cell host & microbe

    Authors: Tonia Akoumianaki, Katerina Vaporidi, Eleni Diamantaki, Frédéric Pène, Remi Beau, Mark S Gresnigt, Marina Gkountzinopulou, Maria Venichaki, Elias Drakos, Jamel El-Benna, George Samonis, Kieu T T Le, Vinod Kumar, Dimitrios Georgopoulos, Frank L van de Veerdonk, Mihai G Netea, Jean-Paul Latge, Georgios Chamilos

  • oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming.

    Immunometabolism

    Authors: Laszlo A Groh, Anaisa V Ferreira, Leonie Helder, Charlotte D C C van der Heijden, Boris Novakovic, Els van de Westerlo, Vasiliki Matzaraki, Simone J C F M Moorlag, L Charlotte de Bree, Valerie A C M Koeken, Vera P Mourits, Samuel T Keating, Jelmer H van Puffelen, Alexander Hoischen, Leo A B Joosten, Mihai G Netea, Werner J H Koopman, Niels P Riksen

  • The Association of TSH and Thyroid Hormones With Lymphopenia in Bacterial Sepsis and COVID-19.

    The Journal of clinical endocrinology and metabolism

    Authors: Inge Grondman, Aline H de Nooijer, Nikolaos Antonakos, Nico A F Janssen, Maria Mouktaroudi, Konstantinos Leventogiannis, Marco Medici, Jan W A Smit, Antonius E van Herwaarden, Leo A B Joosten, Frank L van de Veerdonk, Peter Pickkers, Matthijs Kox, Martin Jaeger, Mihai G Netea, Evangelos J Giamarellos-Bourboulis, Romana T Netea-Maier

  • The role of sirtuin 1 on the induction of trained immunity.

    Cellular immunology

    Authors: Vera P Mourits, Leonie S Helder, Vasiliki Matzaraki, Valerie A C M Koeken, Laszlo Groh, L Charlotte J de Bree, Simone J C F M Moorlag, Charlotte D C C van der Heijden, Samuel T Keating, Jelmer H van Puffelen, Martin Jaeger, Leo A B Joosten, Mihai G Netea

  • Altered Cytokine Responses in Children With Asymptomatic Infection in Burkina Faso: An Additional Argument to Treat Asymptomatic Malaria?

    Frontiers in immunology

    Authors: Annelies Post, Berenger Kaboré, Mike Berendsen, Salou Diallo, Ousmane Traore, Rob J W Arts, Mihai G Netea, Leo A B Joosten, Halidou Tinto, Jan Jacobs, Quirijn de Mast, André van der Ven