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  • Top publication

    A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.

    Nucleic acids research

    Authors: Ann Kristin de Regt, Kanchan Anand, Katrin Ciupka, Felix Bender, Karl Gatterdam, Bastian Putschli, David Fusshöller, Daniel Hilbig, Alexander Kirchhoff, Charlotte Hunkler, Steven Wolter, Agathe Grünewald, Christina Wallerath, Christine Schuberth-Wagner, Janos Ludwig, Katrin Paeschke, Eva Bartok, Gregor Hagelueken, Gunther Hartmann, Thomas Zillinger, Matthias Geyer, Martin Schlee

  • Spectroscopically Orthogonal Labelling to Disentangle Site-Specific Nitroxide Label Distributions.

    Applied magnetic resonance

    Authors: Valentina Vitali, Katrin Ackermann, Gregor Hagelueken, Bela E Bode

  • Adenylation Domain-Guided Recruitment of Acting Nonheme Monooxygenases in Nonribosomal Peptide Biosynthesis.

    ACS chemical biology

    Authors: Daniel A Wirtz, Niels Schneberger, Sophie Klöppel, René Richarz, Matthias Geyer, Gabriele M König, Gregor Hagelueken, Max Crüsemann

  • Top publication

    Antiviral signalling by a cyclic nucleotide activated CRISPR protease.

    Nature

    Authors: Christophe Rouillon, Niels Schneberger, Haotian Chi, Katja Blumenstock, Stefano Da Vela, Katrin Ackermann, Jonas Moecking, Martin F Peter, Wolfgang Boenigk, Reinhard Seifert, Bela E Bode, Jonathan L Schmid-Burgk, Dmitri Svergun, Matthias Geyer, Malcolm F White, Gregor Hagelueken

  • Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.

    The Journal of biological chemistry

    Authors: Jonas Moecking, Pawat Laohamonthonkul, Kubilay Meşe, Gregor Hagelueken, Annemarie Steiner, Cassandra R Harapas, Jarrod J Sandow, Jonathan D Graves, Seth L Masters, Matthias Geyer

  • Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.

    Nature communications

    Authors: Martin F Peter, Jan A Ruland, Peer Depping, Niels Schneberger, Emmanuele Severi, Jonas Moecking, Karl Gatterdam, Sarah Tindall, Alexandre Durand, Veronika Heinz, Jan Peter Siebrasse, Paul-Albert Koenig, Matthias Geyer, Christine Ziegler, Ulrich Kubitscheck, Gavin H Thomas, Gregor Hagelueken

  • Cross-validation of distance measurements in proteins by PELDOR/DEER and single-molecule FRET.

    Nature communications

    Authors: Martin F Peter, Christian Gebhardt, Rebecca Mächtel, Gabriel G Moya Muñoz, Janin Glaenzer, Alessandra Narducci, Gavin H Thomas, Thorben Cordes, Gregor Hagelueken

  • Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.

    Science advances

    Authors: Inga V Hochheiser, Heide Behrmann, Gregor Hagelueken, Juan F Rodríguez-Alcázar, Anja Kopp, Eicke Latz, Elmar Behrmann, Matthias Geyer

  • Top publication

    Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3.

    Nature

    Authors: Inga V Hochheiser, Michael Pilsl, Gregor Hagelueken, Jonas Moecking, Michael Marleaux, Rebecca Brinkschulte, Eicke Latz, Christoph Engel, Matthias Geyer

  • Triggering Closure of a Sialic Acid TRAP Transporter Substrate Binding Protein through Binding of Natural or Artificial Substrates.

    Journal of molecular biology

    Authors: Martin F Peter, Christian Gebhardt, Janin Glaenzer, Niels Schneberger, Marijn de Boer, Gavin H Thomas, Thorben Cordes, Gregor Hagelueken