Bi-allelic variants in CELSR3 are implicated in central nervous system and urinary tract anomalies.
NPJ genomic medicine
Authors:
Jil D Stegmann, Jeshurun C Kalanithy, Gabriel C Dworschak, Nina Ishorst, Enrico Mingardo, Filipa M Lopes, Yee Mang Ho, Phillip Grote, Tobias T Lindenberg, Öznur Yilmaz, Khadija Channab, Steve Seltzsam, Shirlee Shril, Friedhelm Hildebrandt, Felix Boschann, André Heinen, Angad Jolly, Katherine Myers, Kim McBride, Mir Reza Bekheirnia, Nasim Bekheirnia, Marcello Scala, Manuela Morleo, Vincenzo Nigro, Annalaura Torella, Michele Pinelli, Valeria Capra, Andrea Accogli, Silvia Maitz, Alice Spano, Rory J Olson, Eric W Klee, Brendan C Lanpher, Se Song Jang, Jong-Hee Chae, Philipp Steinbauer, Dietmar Rieder, Andreas R Janecke, Julia Vodopiutz, Ida Vogel, Jenny Blechingberg, Jennifer L Cohen, Kacie Riley, Victoria Klee, Laurence E Walsh, Matthias Begemann, Miriam Elbracht, Thomas Eggermann, Arzu Stoppe, Kyra Stuurman, Marjon van Slegtenhorst, Tahsin Stefan Barakat, Maureen S Mulhern, Tristan T Sands, Cheryl Cytrynbaum, Rosanna Weksberg, Federica Isidori, Tommaso Pippucci, Giulia Severi, Francesca Montanari, Michael C Kruer, Somayeh Bakhtiari, Hossein Darvish, Heiko Reutter, Gregor Hagelueken, Matthias Geyer, Adrian S Woolf, Jennifer E Posey, James R Lupski, Benjamin Odermatt, Alina C Hilger
Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP.
Nature communications
Authors:
Martin F Peter, Jan A Ruland, Yeojin Kim, Philipp Hendricks, Niels Schneberger, Jan Peter Siebrasse, Gavin H Thomas, Ulrich Kubitscheck, Gregor Hagelueken
A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
Nucleic acids research
Authors:
Ann Kristin de Regt, Kanchan Anand, Katrin Ciupka, Felix Bender, Karl Gatterdam, Bastian Putschli, David Fusshöller, Daniel Hilbig, Alexander Kirchhoff, Charlotte Hunkler, Steven Wolter, Agathe Grünewald, Christina Wallerath, Christine Schuberth-Wagner, Janos Ludwig, Katrin Paeschke, Eva Bartok, Gregor Hagelueken, Gunther Hartmann, Thomas Zillinger, Matthias Geyer, Martin Schlee
Antiviral signalling by a cyclic nucleotide activated CRISPR protease.
Nature
Authors:
Christophe Rouillon, Niels Schneberger, Haotian Chi, Katja Blumenstock, Stefano Da Vela, Katrin Ackermann, Jonas Moecking, Martin F Peter, Wolfgang Boenigk, Reinhard Seifert, Bela E Bode, Jonathan L Schmid-Burgk, Dmitri Svergun, Matthias Geyer, Malcolm F White, Gregor Hagelueken
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain.
The Journal of biological chemistry
Authors:
Jonas Moecking, Pawat Laohamonthonkul, Kubilay Meşe, Gregor Hagelueken, Annemarie Steiner, Cassandra R Harapas, Jarrod J Sandow, Jonathan D Graves, Seth L Masters, Matthias Geyer
Structural and mechanistic analysis of a tripartite ATP-independent periplasmic TRAP transporter.
Nature communications
Authors:
Martin F Peter, Jan A Ruland, Peer Depping, Niels Schneberger, Emmanuele Severi, Jonas Moecking, Karl Gatterdam, Sarah Tindall, Alexandre Durand, Veronika Heinz, Jan Peter Siebrasse, Paul-Albert Koenig, Matthias Geyer, Christine Ziegler, Ulrich Kubitscheck, Gavin H Thomas, Gregor Hagelueken
Cross-validation of distance measurements in proteins by PELDOR/DEER and single-molecule FRET.
Nature communications
Authors:
Martin F Peter, Christian Gebhardt, Rebecca Mächtel, Gabriel G Moya Muñoz, Janin Glaenzer, Alessandra Narducci, Gavin H Thomas, Thorben Cordes, Gregor Hagelueken