Publications

Re-sequencing of candidate genes FOXF1, HSPA6, HAAO, and KYNU in 522 individuals with VATER/VACTERL, VACTER/VACTERL-like association, and isolated anorectal malformation.

31/03/2022 Birth defects research

Authors: Corina E Thiem, Jil D Stegmann, Alina C Hilger, Lea Waffenschmidt, Charlotte Bendixen, Ricarda Köllges, Eberhard Schmiedeke, Frank-Mattias Schäfer, Martin Lacher, Ferdinand Kosch, Sabine Grasshoff-Derr, Carmen Kabs, Jörg Neser, Ekkehart Jenetzky, Julia Fazaal, Johannes Schumacher, Julia Hoefele, Kerstin U Ludwig, Heiko Reutter

Genetic Predisposition and the Variable Course of Infectious Diseases.

25/02/2022 Deutsches Arzteblatt international

Authors: Axel Schmidt, Ana M Groh, Julia S Frick, Maria J G T Vehreschild, Kerstin U Ludwig

Allele-specific transcription factor binding in a cellular model of orofacial clefting.

02/02/2022 Scientific reports

Authors: Katharina L M Ruff, Ronja Hollstein, Julia Fazaal, Frederic Thieme, Jan Gehlen, Elisabeth Mangold, Michael Knapp, Julia Welzenbach, Kerstin U Ludwig

First genome-wide association study of esophageal atresia identifies three genetic risk loci at , //, and .

25/01/2022 HGG advances

Authors: Jan Gehlen, Ann-Sophie Giel, Ricarda Köllges, Stephan L Haas, Rong Zhang, Jiri Trcka, Ayse Ö Sungur, Florian Renziehausen, Dorothea Bornholdt, Daphne Jung, Paul D Hoyer, Agneta Nordenskjöld, Dick Tibboel, John Vlot, Manon C W Spaander, Robert Smigiel, Dariusz Patkowski, Nel Roeleveld, Iris Alm van Rooij, Ivo de Blaauw, Alice Hölscher, Marcus Pauly, Andreas Leutner, Joerg Fuchs, Joel Niethammer, Maria-Theodora Melissari, Ekkehart Jenetzky, Nadine Zwink, Holger Thiele, Alina Christine Hilger, Timo Hess, Jessica Trautmann, Matthias Marks, Martin Baumgarten, Gaby Bläss, Mikael Landén, Bengt Fundin, Cynthia M Bulik, Tracie Pennimpede, Michael Ludwig, Kerstin U Ludwig, Elisabeth Mangold, Stefanie Heilmann-Heimbach, Susanne Moebus, Bernhard G Herrmann, Kristina Alsabeah, Carmen M Burgos, Helene E Lilja, Sahar Azodi, Pernilla Stenström, Einar Arnbjörnsson, Barbora Frybova, Dariusz M Lebensztejn, Wojciech Debek, Elwira Kolodziejczyk, Katarzyna Kozera, Jaroslaw Kierkus, Piotr Kaliciński, Marek Stefanowicz, Anna Socha-Banasiak, Michal Kolejwa, Anna Piaseczna-Piotrowska, Elzbieta Czkwianianc, Markus M Nöthen, Phillip Grote, Michal Rygl, Konrad Reinshagen, Nicole Spychalski, Barbara Ludwikowski, Jochen Hubertus, Andreas Heydweiller, Benno Ure, Oliver J Muensterer, Ophelia Aubert, Jan-Hendrik Gosemann, Martin Lacher, Petra Degenhardt, Thomas M Boemers, Anna Mokrowiecka, Ewa Małecka-Panas, Markus Wöhr, Michael Knapp, Guido Seitz, Annelies de Klein, Grzegorz Oracz, Erwin Brosens, Heiko Reutter, Johannes Schumacher

Resequencing of VEGFR3 pathway genes implicate GJC2 and FLT4 in the formation of primary congenital chylothorax.

07/01/2022 American journal of medical genetics. Part A

Authors: Sophia Schneider, Ricarda Köllges, Jil D Stegmann, Frederic Thieme, Alina C Hilger, Lea Waffenschmidt, Julia Fazaal, Jeshurun C Kalanithy, Annegret Geipel, Brigitte Strizek, Kerstin U Ludwig, Heiko Reutter, Andreas Müller

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity.

10/12/2021 Human genetics

Authors: Chiara Fallerini, Nicola Picchiotti, Margherita Baldassarri, Kristina Zguro, Sergio Daga, Francesca Fava, Elisa Benetti, Sara Amitrano, Mirella Bruttini, Maria Palmieri, Susanna Croci, Mirjam Lista, Giada Beligni, Floriana Valentino, Ilaria Meloni, Marco Tanfoni, Francesca Minnai, Francesca Colombo, Enrico Cabri, Maddalena Fratelli, Chiara Gabbi, Stefania Mantovani, Elisa Frullanti, Marco Gori, Francis P Crawley, Guillaume Butler-Laporte, Brent Richards, Hugo Zeberg, Miklos Lipcsey, Michael Hultström, Kerstin U Ludwig, Eva C Schulte, Erola Pairo-Castineira, John Kenneth Baillie, Axel Schmidt, Robert Frithiof, Francesca Mari, Alessandra Renieri, Simone Furini

Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality.

01/12/2021 The Journal of clinical investigation

Authors: Tomoko Nakanishi, Sara Pigazzini, Frauke Degenhardt, Mattia Cordioli, Guillaume Butler-Laporte, Douglas Maya-Miles, Luis Bujanda, Youssef Bouysran, Mari Ek Niemi, Adriana Palom, David Ellinghaus, Atlas Khan, Manuel Martínez-Bueno, Selina Rolker, Sara Amitrano, Luisa Roade Tato, Francesca Fava, Christoph D Spinner, Daniele Prati, David Bernardo, Federico Garcia, Gilles Darcis, Israel Fernández-Cadenas, Jan Cato Holter, Jesus M Banales, Robert Frithiof, Krzysztof Kiryluk, Stefano Duga, Rosanna Asselta, Alexandre C Pereira, Manuel Romero-Gómez, Beatriz Nafría-Jiménez, Johannes R Hov, Isabelle Migeotte, Alessandra Renieri, Anna M Planas, Kerstin U Ludwig, Maria Buti, Souad Rahmouni, Marta E Alarcón-Riquelme, Eva C Schulte, Andre Franke, Tom H Karlsen, Luca Valenti, Hugo Zeberg, J Brent Richards, Andrea Ganna

Iron Deficiency Caused by Intestinal Iron Loss-Novel Candidate Genes for Severe Anemia.

24/11/2021 Genes

Authors: Carolina Huettmann, Matthias Stelljes, Sugirthan Sivalingam, Manfred Fobker, Alexis Vrachimis, Anne Exler, Christian Wenning, Carola Wempe, Matthias Penke, Andreas Buness, Kerstin U Ludwig, Martina U Muckenthaler, Andrea U Steinbicker

TBK1 and TNFRSF13B mutations and an autoinflammatory disease in a child with lethal COVID-19.

01/07/2021 NPJ genomic medicine

Authors: Axel Schmidt, Sophia Peters, Alexej Knaus, Hemmen Sabir, Frauke Hamsen, Carlo Maj, Julia Fazaal, Sugirthan Sivalingam, Oleksandr Savchenko, Aakash Mantri, Dirk Holzinger, Ulrich Neudorf, Andreas Müller, Kerstin U Ludwig, Peter M Krawitz, Hartmut Engels, Markus M Nöthen, Soyhan Bagci

Publication categories: Top publication

LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding.

29/06/2021 Nature biotechnology

Authors: Kerstin U Ludwig, Ricarda M Schmithausen, David Li, Max L Jacobs, Ronja Hollstein, Katja Blumenstock, Jana Liebing, Mikołaj Słabicki, Amir Ben-Shmuel, Ofir Israeli, Shay Weiss, Thomas S Ebert, Nir Paran, Wibke Rüdiger, Gero Wilbring, David Feldman, Bärbel Lippke, Nina Ishorst, Lara M Hochfeld, Eva C Beins, Ines H Kaltheuner, Maximilian Schmitz, Aliona Wöhler, Manuel Döhla, Esther Sib, Marius Jentzsch, Eva-Maria C Moench, Jacob D Borrajo, Jonathan Strecker, Julia Reinhardt, Brian Cleary, Matthias Geyer, Michael Hölzel, Rhiannon Macrae, Markus M Nöthen, Per Hoffmann, Martin Exner, Aviv Regev, Feng Zhang, Jonathan L Schmid-Burgk