Publications

A simple approach for detecting HLA-A*02 alleles in archival formalin-fixed paraffin-embedded tissue samples and an application example for studying cancer immunoediting.

25/10/2022 HLA

Authors: Johannes Witt, Saskia Haupt, Aysel Ahadova, Lena Bohaumilitzky, Vera Fuchs, Alexej Ballhausen, Moritz Jakob Przybilla, Michael Jendrusch, Toni T Seppälä, Daniel Fürst, Thomas Walle, Elena Busch, Georg Martin Haag, Robert Hüneburg, Jacob Nattermann, Magnus von Knebel Doeberitz, Vincent Heuveline, Matthias Kloor

Is HLA type a possible cancer risk modifier in Lynch syndrome?

14/10/2022 International journal of cancer

Authors: Aysel Ahadova, Johannes Witt, Saskia Haupt, Richard Gallon, Robert Hüneburg, Jacob Nattermann, Sanne Ten Broeke, Lena Bohaumilitzky, Alejandro Hernandez-Sanchez, Mauro Santibanez-Koref, Michael S Jackson, Maarit Ahtiainen, Kirsi Pylvänäinen, Katarina Andini, Vince Kornel Grolmusz, Gabriela Möslein, Mev Dominguez-Valentin, Pål Møller, Daniel Fürst, Rolf Sijmons, Gillian M Borthwick, John Burn, Jukka-Pekka Mecklin, Vincent Heuveline, Magnus von Knebel Doeberitz, Toni Seppälä, Matthias Kloor

Mitochondrial Dysfunction Contributes to Impaired Cytokine Production of CD56bright Natural Killer Cells From Human Immunodeficiency Virus-Infected Individuals Under Effective Antiretroviral Therapy.

13/09/2022 The Journal of infectious diseases

Authors: Michael ToVinh, Gregor Hörr, Kristiyana Dobrikova, Christina Gotter, Clemens Rommel, Christoph Hoffmeister, Jan Raabe, Kim M Kaiser, Claudia Finnemann, Jenny Bischoff, Gereon J Rieke, Christoph Wilhelm, Vanessa Schmitt, Christoph Möhl, Mansoureh Aghabeig, Carolynne Schwarze-Zander, Christoph Boesecke, Kathrin van Bremen, Jan Christian Wasmuth, Christian P Strassburg, Jürgen K Rockstroh, Ulrich Spengler, Benjamin Krämer, Jacob Nattermann

Genetic variation in modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.

04/07/2022 Gut

Authors: Stephan Buch, Hamish Innes, Philipp Ludwig Lutz, Hans Dieter Nischalke, Jens U Marquardt, Janett Fischer, Karl Heinz Weiss, Jonas Rosendahl, Astrid Marot, Marcin Krawczyk, Markus Casper, Frank Lammert, Florian Eyer, Arndt Vogel, Silke Marhenke, Johann von Felden, Rohini Sharma, Stephen Rahul Atkinson, Andrew McQuillin, Jacob Nattermann, Clemens Schafmayer, Andre Franke, Christian Strassburg, Marcella Rietschel, Heidi Altmann, Stefan Sulk, Veera Raghavan Thangapandi, Mario Brosch, Carolin Lackner, Rudolf E Stauber, Ali Canbay, Alexander Link, Thomas Reiberger, Mattias Mandorfer, Georg Semmler, Bernhard Scheiner, Christian Datz, Stefano Romeo, Stefano Ginanni Corradini, William Lucien Irving, Joanne R Morling, Indra Neil Guha, Eleanor Barnes, M Azim Ansari, Jocelyn Quistrebert, Luca Valenti, Sascha A Müller, Marsha Yvonne Morgan, Jean-François Dufour, Jonel Trebicka, Thomas Berg, Pierre Deltenre, Sebastian Mueller, Jochen Hampe, Felix Stickel

Natural Killer Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Against SARS-CoV-2 After Natural Infection Is More Potent Than After Vaccination.

16/05/2022 The Journal of infectious diseases

Authors: Gereon J Rieke, Kathrin van Bremen, Jenny Bischoff, Michael ToVinh, Malte B Monin, Stefan Schlabe, Jan Raabe, Kim M Kaiser, Claudia Finnemann, Alexandru Odainic, Anushka Kudaliyanage, Eicke Latz, Christian P Strassburg, Christoph Boesecke, Susanne V Schmidt, Benjamin Krämer, Jürgen K Rockstroh, Jacob Nattermann

COVID-19 mortality in cirrhosis is determined by cirrhosis-associated comorbidities and extrahepatic organ failure: Results from the multinational LEOSS registry.

28/04/2022 United European gastroenterology journal

Authors: Jonathan F Brozat, Frank Hanses, Martina Haelberger, Melanie Stecher, Michael Dreher, Lukas Tometten, Maria M Ruethrich, Janne J Vehreschild, Christian Trautwein, Stefan Borgmann, Maria J G T Vehreschild, Carolin E M Jakob, Andreas Stallmach, Kai Wille, Kerstin Hellwig, Nora Isberner, Philipp A Reuken, Fabian Geisler, Jacob Nattermann, Tony Bruns

Impact of regular additional endobiliary radiofrequency ablation on survival of patients with advanced extrahepatic cholangiocarcinoma under systemic chemotherapy.

19/01/2022 Scientific reports

Authors: Maria A Gonzalez-Carmona, Christian Möhring, Robert Mahn, Taotao Zhou, Alexandra Bartels, Farsaneh Sadeghlar, Maximilian Bolch, Annabelle Vogt, Dominik J Kaczmarek, Dominik J Heling, Leona Dold, Jacob Nattermann, Vittorio Branchi, Hanno Matthaei, Steffen Manekeller, Jörg C Kalff, Christian P Strassburg, Raphael U Mohr, Tobias J Weismüller

Liver Fibrosis-From Mechanisms of Injury to Modulation of Disease.

11/01/2022 Frontiers in medicine

Authors: Christian Liedtke, Yulia A Nevzorova, Tom Luedde, Henning Zimmermann, Daniela Kroy, Pavel Strnad, Marie-Luise Berres, Jürgen Bernhagen, Frank Tacke, Jacob Nattermann, Ulrich Spengler, Tilman Sauerbruch, Alexander Wree, Zeinab Abdullah, René H Tolba, Jonel Trebicka, Twan Lammers, Christian Trautwein, Ralf Weiskirchen

Complement activation induces excessive T cell cytotoxicity in severe COVID-19.

28/12/2021 Cell

Authors: Philipp Georg, Rosario Astaburuaga-García, Lorenzo Bonaguro, Sophia Brumhard, Laura Michalick, Lena J Lippert, Tomislav Kostevc, Christiane Gäbel, Maria Schneider, Mathias Streitz, Vadim Demichev, Ioanna Gemünd, Matthias Barone, Pinkus Tober-Lau, Elisa T Helbig, David Hillus, Lev Petrov, Julia Stein, Hannah-Philine Dey, Daniela Paclik, Christina Iwert, Michael Mülleder, Simran Kaur Aulakh, Sonja Djudjaj, Roman D Bülow, Henrik E Mei, Axel R Schulz, Andreas Thiel, Stefan Hippenstiel, Antoine-Emmanuel Saliba, Roland Eils, Irina Lehmann, Marcus A Mall, Sebastian Stricker, Jobst Röhmel, Victor M Corman, Dieter Beule, Emanuel Wyler, Markus Landthaler, Benedikt Obermayer, Saskia von Stillfried, Peter Boor, Münevver Demir, Hans Wesselmann, Norbert Suttorp, Alexander Uhrig, Holger Müller-Redetzky, Jacob Nattermann, Wolfgang M Kuebler, Christian Meisel, Markus Ralser, Joachim L Schultze, Anna C Aschenbrenner, Charlotte Thibeault, Florian Kurth, Leif E Sander, Nils Blüthgen, Birgit Sawitzki

The Different Immune Profiles of Normal Colonic Mucosa in Cancer-Free Lynch Syndrome Carriers and Lynch Syndrome Colorectal Cancer Patients.

02/12/2021 Gastroenterology

Authors: Lena Bohaumilitzky, Klaus Kluck, Robert Hüneburg, Richard Gallon, Jacob Nattermann, Martina Kirchner, Glen Kristiansen, Oliver Hommerding, Pauline L Pfuderer, Lelia Wagner, Fabian Echterdiek, Svenja Kösegi, Nico Müller, Konstantin Fischer, Nina Nelius, Ben Hartog, Gillian Borthwick, Elena Busch, Georg Martin Haag, Hendrik Bläker, Gabriela Möslein, Magnus von Knebel Doeberitz, Toni T Seppälä, Maarit Ahtiainen, Jukka-Pekka Mecklin, D Timothy Bishop, John Burn, Albrecht Stenzinger, Jan Budczies, Matthias Kloor, Aysel Ahadova