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featured publications

  • Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.

    Genome medicine

    Authors: Anna C Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer, Marie Oestreich, Nikolaos Antonakos, Melanie Nuesch-Germano, Konstantina Gkizeli, Lorenzo Bonaguro, Nico Reusch, Kevin Baßler, Maria Saridaki, Rainer Knoll, Tal Pecht, Theodore S Kapellos, Sarandia Doulou, Charlotte Kröger, Miriam Herbert, Lisa Holsten, Arik Horne, Ioanna D Gemünd, Nikoletta Rovina, Shobhit Agrawal, Kilian Dahm, Martina van Uelft, Anna Drews, Lena Lenkeit, Niklas Bruse, Jelle Gerretsen, Jannik Gierlich, Matthias Becker, Kristian Händler, Michael Kraut, Heidi Theis, Simachew Mengiste, Elena De Domenico, Jonas Schulte-Schrepping, Lea Seep, Jan Raabe, Christoph Hoffmeister, Michael ToVinh, Verena Keitel, Gereon Rieke, Valentina Talevi, Dirk Skowasch, N Ahmad Aziz, Peter Pickkers, Frank L van de Veerdonk, Mihai G Netea, Joachim L Schultze, Matthijs Kox, Monique M B Breteler, Jacob Nattermann, Antonia Koutsoukou, Evangelos J Giamarellos-Bourboulis, Thomas Ulas

  • Solid organ transplantation is not a risk factor for COVID-19 disease outcome.

    Transplant international : official journal of the European Society for Organ Transplantation

    Authors: Christian Hugo, Melanie Stecher, Sebastian Dolff, Jacob Nattermann, Jörg Vehreschild, Theresa Hippchen, Timm Westhoff, Martina Bertolo, Bernd Hohenstein, Frank Hanses, Christian Strassburg

  • Hereditary Diffuse Gastric Cancer: A Comparative Cohort Study According to Pathogenic Variant Status.

    Cancers

    Authors: Tim Marwitz, Robert Hüneburg, Isabel Spier, Jan-Frederic Lau, Glen Kristiansen, Philipp Lingohr, Jörg C Kalff, Stefan Aretz, Jacob Nattermann, Christian P Strassburg

  • Top publication

    Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

    Immunity

    Authors: Joana P Bernardes, Neha Mishra, Florian Tran, Thomas Bahmer, Lena Best, Johanna I Blase, Dora Bordoni, Jeanette Franzenburg, Ulf Geisen, Jonathan Josephs-Spaulding, Philipp Köhler, Axel Künstner, Elisa Rosati, Anna C Aschenbrenner, Petra Bacher, Nathan Baran, Teide Boysen, Burkhard Brandt, Niklas Bruse, Jonathan Dörr, Andreas Dräger, Gunnar Elke, David Ellinghaus, Julia Fischer, Michael Forster, Andre Franke, Sören Franzenburg, Norbert Frey, Anette Friedrichs, Janina Fuß, Andreas Glück, Jacob Hamm, Finn Hinrichsen, Marc P Hoeppner, Simon Imm, Ralf Junker, Sina Kaiser, Ying H Kan, Rainer Knoll, Christoph Lange, Georg Laue, Clemens Lier, Matthias Lindner, Georgios Marinos, Robert Markewitz, Jacob Nattermann, Rainer Noth, Peter Pickkers, Klaus F Rabe, Alina Renz, Christoph Röcken, Jan Rupp, Annika Schaffarzyk, Alexander Scheffold, Jonas Schulte-Schrepping, Domagoj Schunk, Dirk Skowasch, Thomas Ulas, Klaus-Peter Wandinger, Michael Wittig, Johannes Zimmermann, Hauke Busch, Bimba F Hoyer, Christoph Kaleta, Jan Heyckendorf, Matthijs Kox, Jan Rybniker, Stefan Schreiber, Joachim L Schultze, Philip Rosenstiel

  • Transpapillary tissue sampling of biliary strictures: balloon dilatation prior to forceps biopsy improves sensitivity and accuracy.

    Scientific reports

    Authors: Daniel Pörner, Dominik J Kaczmarek, Dominik Heling, Annekristin Hausen, Raphael Mohr, Robert Hüneburg, Hanno Matthaei, Tim R Glowka, Steffen Manekeller, Hans-Peter Fischer, Marieta Toma, Jacob Nattermann, Christian P Strassburg, Maria A Gonzalez-Carmona, Tobias J Weismüller

  • Value of upper gastrointestinal endoscopy for gastric cancer surveillance in patients with Lynch syndrome.

    International journal of cancer

    Authors: Swetlana Ladigan-Badura, Deepak B Vangala, Christoph Engel, Karolin Bucksch, Robert Hueneburg, Claudia Perne, Jacob Nattermann, Verena Steinke-Lange, Nils Rahner, Hans K Schackert, Jürgen Weitz, Matthias Kloor, Judith Kuhlkamp, Huu Phuc Nguyen, Gabriela Moeslein, Christian Strassburg, Monika Morak, Elke Holinski-Feder, Reinhard Buettner, Stefan Aretz, Markus Loeffler, Wolff Schmiegel, Christian Pox, Karsten Schulmann

  • Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease.

    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

    Authors: Olaf Tyc, Christian Jansen, Robert Schierwagen, Frank Erhard Uschner, Mads Israelsen, Sabine Klein, Cristina Ortiz, Christian P Strassburg, Stefan Zeuzem, Wenyi Gu, Sandra Torres, Michael Praktiknjo, Stephan Kersting, Melanie Langheinrich, Jacob Nattermann, Florence Servant, Manimozhiyan Arumugam, Aleksander Krag, Benjamin Lelouvier, Tobias J Weismüller, Jonel Trebicka

  • First results of the "Lean European Open Survey on SARS-CoV-2-Infected Patients (LEOSS)".

    Infection

    Authors: Carolin E M Jakob, Stefan Borgmann, Fazilet Duygu, Uta Behrends, Martin Hower, Uta Merle, Anette Friedrichs, Lukas Tometten, Frank Hanses, Norma Jung, Siegbert Rieg, Kai Wille, Beate Grüner, Hartwig Klinker, Nicole Gersbacher-Runge, Kerstin Hellwig, Lukas Eberwein, Sebastian Dolff, Dominic Rauschning, Michael von Bergwelt-Baildon, Julia Lanznaster, Richard Strauß, Janina Trauth, Katja de With, Maria Ruethrich, Catherina Lueck, Jacob Nattermann, Lene Tscharntke, Lisa Pilgram, Sandra Fuhrmann, Annika Classen, Melanie Stecher, Maximilian Schons, Christoph Spinner, Jörg Janne Vehreschild

  • Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment.

    Cell

    Authors: Jonas Schulte-Schrepping, Nico Reusch, Daniela Paclik, Kevin Baßler, Stephan Schlickeiser, Bowen Zhang, Benjamin Krämer, Tobias Krammer, Sophia Brumhard, Lorenzo Bonaguro, Elena De Domenico, Daniel Wendisch, Martin Grasshoff, Theodore S Kapellos, Michael Beckstette, Tal Pecht, Adem Saglam, Oliver Dietrich, Henrik E Mei, Axel R Schulz, Claudia Conrad, Désirée Kunkel, Ehsan Vafadarnejad, Cheng-Jian Xu, Arik Horne, Miriam Herbert, Anna Drews, Charlotte Thibeault, Moritz Pfeiffer, Stefan Hippenstiel, Andreas Hocke, Holger Müller-Redetzky, Katrin-Moira Heim, Felix Machleidt, Alexander Uhrig, Laure Bosquillon de Jarcy, Linda Jürgens, Miriam Stegemann, Christoph R Glösenkamp, Hans-Dieter Volk, Christine Goffinet, Markus Landthaler, Emanuel Wyler, Philipp Georg, Maria Schneider, Chantip Dang-Heine, Nick Neuwinger, Kai Kappert, Rudolf Tauber, Victor Corman, Jan Raabe, Kim Melanie Kaiser, Michael To Vinh, Gereon Rieke, Christian Meisel, Thomas Ulas, Matthias Becker, Robert Geffers, Martin Witzenrath, Christian Drosten, Norbert Suttorp, Christof von Kalle, Florian Kurth, Kristian Händler, Joachim L Schultze, Anna C Aschenbrenner, Yang Li, Jacob Nattermann, Birgit Sawitzki, Antoine-Emmanuel Saliba, Leif Erik Sander

  • The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance.

    International journal of cancer

    Authors: Aysel Ahadova, Toni T Seppälä, Christoph Engel, Richard Gallon, John Burn, Elke Holinski-Feder, Verena Steinke-Lange, Gabriela Möslein, Maartje Nielsen, Sanne W Ten Broeke, Luigi Laghi, Mev Dominguez-Valentin, Gabriel Capella, Finlay Macrae, Rodney Scott, Robert Hüneburg, Jacob Nattermann, Michael Hoffmeister, Hermann Brenner, Hendrik Bläker, Magnus von Knebel Doeberitz, Julian R Sampson, Hans Vasen, Jukka-Pekka Mecklin, Pål Møller, Matthias Kloor